在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Acetylcholine receptor subunit gamma (CHRNG), partial

In Stock
  • 貨號(hào):
    CSB-EP005401HU
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    CHRNG
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    E.coli
  • 分子量:
    29.6 kDa
  • 表達(dá)區(qū)域:
    23-240aa
  • 氨基酸序列
    RNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTIEWIFIDPEAFTENGEWAIQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 基因功能參考文獻(xiàn):
    1. CHRNG mutations associated with interfamilial variability of the severity of the Escobar variant of multiple pterygium syndrome PMID: 27245440
    2. Two siblings with Escobar syndrome caused by homozygous mutations of the CHRNG gene were identified. PMID: 25411939
    3. Rare cases of congenital arthrogryposis multiplex caused by novel recurrent CHRNG mutations. PMID: 25608830
    4. We did not identify a clear difference in mutation spectrum of the CHRNG gene between lethal form and non-lethal forms of multiple pterygium syndromes PMID: 22167768
    5. CHRNG mutations identified in families with Escobar syndrome show that the trait is a congenital dysmorphology caused by transient inactivation of the neuromuscular endplate. PMID: 16826520
    6. Mutations cxause lethal and nonlethal forms of multiple pterygium syndrome. PMID: 16826531
    7. constructed and characterized four AChR gamma extracellular domain variants PMID: 18502212
    8. This study suggests for the first time in humans, a possible role for genetic variation in the neuromuscular nicotinic acetylcholine receptor, particularly the gamma subunit, in systolic blood pressure regulation PMID: 18625075
    9. Detection of PAX3/7-FKHR fusion gene by one-step RT-PCR is useful in the diagnosis of rhabdomyosarcomas (RMS) and that AChR-gamma is overexpressed in Chinese RMS patients. PMID: 18988640

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
  • 亞細(xì)胞定位:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Gamma/CHRNG sub-subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 1967

    OMIM: 100730

    KEGG: hsa:1146

    STRING: 9606.ENSP00000374145

    UniGene: Hs.248101



主站蜘蛛池模板: 久久久久99精品成人片牛牛影视 | 精品香蕉99久久久久网站| 巨乳美乳一区二区三区| 免费观看黄网站在线播放| www片香蕉内射在线88av8| 免费一区二区三区成人免费视频| 亚洲国产成人久久一区| 久久av无码精品人妻出轨| 又大又黄又粗又爽的免费视频| 久久精品国产首页027007| 特级a欧美做爰片第一次| 四虎国产精品永久在线观看| 亚洲久悠悠色悠在线播放| 无线日本视频精品| 小鲜肉洗澡时自慰网站xnxx | 中文字幕无线观看不卡网站| 日本三级香港三级三级人!妇久| 久久中文字幕人妻熟av女| 国产精品无码av天天爽播放器| 亚洲精品成人网线在线播放va| 午夜激成人免费视频在线观看| 99久久婷婷国产综合精品青草免费| 国产精品久久久久久麻豆一区| 爽爽午夜影视窝窝看片| 欧美成人午夜免费影院手机在线看| 欧美国产一区二区三区激情无套| 亚洲欧洲成人av每日更新| 又大又粗又爽免费视频a片| 无码人妻丰满熟妇区bbbbxxxx| 巨胸不知火舞露双奶头无遮挡| 欧美va亚洲va在线观看日本| 97se亚洲国产综合自在线| 精品人妻系列无码一区二区三区| 98国产精品综合一区二区三区| 秋秋影视午夜福利高清| 综合亚洲桃色第一影院| 老熟女乱子伦| 欧美粗大猛烈老熟妇| 天天躁日日躁狠狠躁性色av| 亚洲老妈激情一区二区三区| 亚洲色欲久久久久综合网|