在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ATPase family AAA domain-containing protein 5 (ATAD5), partial

  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-YP839400HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-EP839400HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-EP839400HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-BP839400HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-MP839400HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ATAD5
  • Uniprot No.:
  • 別名:
    ATAD5; ATAD5_HUMAN; ATPase family AAA domain containing 5; ATPase family AAA domain-containing protein 5; C17orf41; chromosome fragility associated gene 1; Chromosome fragility-associated gene 1 protein; ELG1; Enhanced level of genomic instability 1 homolog; FRAG1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
  • 基因功能參考文獻:
    1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma. PMID: 27045477
    2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
    3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA levels on chromatin, thereby acting as a PCNA unloading factor. PMID: 23937667
    4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity. PMID: 23277426
    5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
    6. Studies indicate that USP1 and ELG1 as regulators of PCNA ubiquitylation. PMID: 21640107
    7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci. PMID: 19755857
    8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. PMID: 15983387

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    AAA ATPase family
  • 數據庫鏈接:

    HGNC: 25752

    OMIM: 609534

    KEGG: hsa:79915

    STRING: 9606.ENSP00000313171

    UniGene: Hs.528902



主站蜘蛛池模板: 国产av丝袜一区二区三区| 国产亚洲精品久久久久久小舞| 加勒比一本heyzo高清视频| 亚洲vs日韩vs欧美vs久久| 寂寞人妻瑜伽被教练日| 午夜福利av无码一区二区| 成人无码av片在线观看| 无码精品日韩中文字幕| 中字幕视频在线永久在线| 丰满岳乱妇久久久| 最爽free性欧美人妖| 久久/这里只精品热在线获取| 国产女精品视频网站免费| 欧美巨大xxxx做受中文字幕| 久久这里精品国产99丫e6| 国产真实夫妇交换视频| 天堂av无码大芭蕉伊人av不卡| 国产成人年无码av片在线观看| 亚洲精品av无码喷奶水网站| 国产色xx群视频射精| 亚洲久久中文字幕www网站| 中文字幕丰满乱子无码视频| 好爽好黄的视频| 国产熟妇与子伦hd| 成人亚洲精品久久99狠狠| 亚洲成年看片在线观看| 日本va欧美va欧美va精品| 香蕉伊蕉伊中文视频在线| 韩国的无码av看免费大片在线| 天天爽夜夜爽人人爽免费| 成 人片 黄 色 大 片| 男女裸体下面进入的免费视频 | 国产专区一线二线三线码| 亚洲欧美第一成人网站7777| 少妇太爽了在线观看免费视频| 日本成熟老妇乱| 欧美精品a∨在线观看| 国产成人女人在线观看| 黑人巨茎大战欧美白妇| 亚洲乱码日产精品bd在| 国产成人a∨激情视频厨房|