在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ATPase family AAA domain-containing protein 5 (ATAD5), partial

  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-YP839400HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-EP839400HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-EP839400HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-BP839400HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human ATPase family AAA domain-containing protein 5(ATAD5) ,partial
  • 貨號:
    CSB-MP839400HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ATAD5
  • Uniprot No.:
  • 別名:
    ATAD5; ATAD5_HUMAN; ATPase family AAA domain containing 5; ATPase family AAA domain-containing protein 5; C17orf41; chromosome fragility associated gene 1; Chromosome fragility-associated gene 1 protein; ELG1; Enhanced level of genomic instability 1 homolog; FRAG1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
  • 基因功能參考文獻:
    1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma. PMID: 27045477
    2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
    3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA levels on chromatin, thereby acting as a PCNA unloading factor. PMID: 23937667
    4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity. PMID: 23277426
    5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
    6. Studies indicate that USP1 and ELG1 as regulators of PCNA ubiquitylation. PMID: 21640107
    7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci. PMID: 19755857
    8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. PMID: 15983387

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    AAA ATPase family
  • 數據庫鏈接:

    HGNC: 25752

    OMIM: 609534

    KEGG: hsa:79915

    STRING: 9606.ENSP00000313171

    UniGene: Hs.528902



主站蜘蛛池模板: 男女爽爽无遮挡午夜视频| 中文字幕乱码一区av久久| 午夜视频无码国产在线观看| 少妇性荡欲视频| 亚洲欧美日韩v在线观看不卡| 亚洲欧美国产精品专区久久| 97影院理论片手机在线观看| www激情内射在线看| 国产精品992tv在线观看| 久久精品aⅴ无码中文字字幕蜜桃| 特级做a爰片毛片免费看108| 国产成人午夜福利在线小电影| 日韩在线 | 中文| 色偷偷色噜噜狠狠网站久久| 四虎亚洲中文字幕无码永久| 青青草国产精品欧美成人| 亚洲嫩模喷白浆在线观看| 996热re视频精品视频这里| 亚洲综合国产一区二区三区| 一本精品99久久精品77| 久久精品日韩av无码| 桃花色综合影院| 一边捏奶头一边啪高潮视频| 国产l精品国产亚洲区| 国产狂喷潮在线观看| 国产精品永久免费视频| 国产成人精品久久久久精品日日| 人妻无码专区一区二区三区| 亚洲爆乳无码专区| 少妇午夜啪爽嗷嗷叫视频| 中文字幕亚洲男人的天堂网络| 女女女女女裸体处开bbb| 国产精品久久久久7777| 国产福利姬喷水福利在线观看| 免费午夜男女高清视频| 玩弄japan白嫩少妇hd小说| 夜色福利院在线观看免费| 最近中文字幕mv在线视频看 | 欧美日韩一本无线码专区| 2019日韩中文字幕mv| 无码中文字幕日韩专区|