在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATAD5 Antibody

ATAD5 Antibody

  • 中文名稱：
    ATAD5兔多克隆抗體
  • 貨號：
    CSB-PA119643
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: CSB-PA119643(ATAD5 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ATAD5
  • 別名：
    ATAD5 antibody; ATAD5_HUMAN antibody; ATPase family AAA domain containing 5 antibody; ATPase family AAA domain-containing protein 5 antibody; C17orf41 antibody; chromosome fragility associated gene 1 antibody; Chromosome fragility-associated gene 1 protein antibody; ELG1 antibody; Enhanced level of genomic instability 1 homolog antibody; FRAG1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human ATAD5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
  • 基因功能參考文獻：
    1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma. PMID: 27045477
    2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
    3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA levels on chromatin, thereby acting as a PCNA unloading factor. PMID: 23937667
    4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity. PMID: 23277426
    5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
    6. Studies indicate that USP1 and ELG1 as regulators of PCNA ubiquitylation. PMID: 21640107
    7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci. PMID: 19755857
    8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. PMID: 15983387

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數據庫鏈接：

    HGNC: 25752

    OMIM: 609534

    KEGG: hsa:79915

    STRING: 9606.ENSP00000313171

    UniGene: Hs.528902



主站蜘蛛池模板： 国内老熟妇对白hdxxxx| 成人精品一区二区三区在线观看 | 欧洲精品免费一区二区三区| 香港三级精品三级在线专区| 内射人妻无套中出无码| 99久久国语露脸精品国产| 国产免费午夜福利在线播放11| 中文字幕 乱码 中文乱码视频| 公与淑婷厨房猛烈进出视频免费| 77777_亚洲午夜久久多人| 男女啪祼交视频| 国产 | 欧洲野花视频欧洲1| 成 人 社区在线视频| 乱人伦中文无码视频| 人妻少妇中文字幕久久| 国产产无码乱码精品久久鸭| 国产成人亚洲精品无码最新| 亚洲成av人片无码迅雷下载| 久久久无码一区二区三区| 国产精品亚洲片在线观看不卡| 亚洲欧美日韩_欧洲日韩| 精品久久综合1区2区3区激情| 初尝人妻少妇中文字幕| 成人午夜亚洲精品无码区毛片| 99热这里只有是精品2| 国产精品福利一区二区| 人妻熟女一区二区aⅴ向井蓝| 国产精品白浆在线观看免费| 欧美性生交活xxxxxdddd| 国内精品一区二区三区| 欧美熟妇性xxx交潮喷| 午夜亚洲国产理论片二级港台二级| 少妇被粗大猛进进出出| 人人妻人人澡人人爽人人精品av| 免费国产在线一区二区| 九九视频麻婆豆腐在线观看| 免费拍拍拍网站| 夜夜爽一区二区三区精品| 久久本色成人综合网| 久久精品国产精品亚洲蜜月| 亚洲日韩国产成网在线观看|