在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATAD5 Antibody

ATAD5 Antibody

  • 中文名稱：
    ATAD5兔多克隆抗體
  • 貨號：
    CSB-PA052246
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: CSB-PA052246(ATAD5 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ATAD5
  • 別名：
    ATAD5 antibody; ATAD5_HUMAN antibody; ATPase family AAA domain containing 5 antibody; ATPase family AAA domain-containing protein 5 antibody; C17orf41 antibody; chromosome fragility associated gene 1 antibody; Chromosome fragility-associated gene 1 protein antibody; ELG1 antibody; Enhanced level of genomic instability 1 homolog antibody; FRAG1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human ATAD5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
  • 基因功能參考文獻：
    1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma. PMID: 27045477
    2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
    3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA levels on chromatin, thereby acting as a PCNA unloading factor. PMID: 23937667
    4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity. PMID: 23277426
    5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
    6. Studies indicate that USP1 and ELG1 as regulators of PCNA ubiquitylation. PMID: 21640107
    7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci. PMID: 19755857
    8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. PMID: 15983387

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數據庫鏈接：

    HGNC: 25752

    OMIM: 609534

    KEGG: hsa:79915

    STRING: 9606.ENSP00000313171

    UniGene: Hs.528902



主站蜘蛛池模板： 亚洲中文字慕日产2021| 国产精品亚洲成在人线| 亚洲性无码一区二区三区| 少妇呻吟白浆高潮啪啪69| 强行无套内谢大学生初次| 少妇太爽了在线观看免费视频 | 亚洲大尺度无码专区尤物| 日本内射精品一区二区视频| 欧美日韩精品无码一本二本三本色 | 日韩国产综合精选| 久久久精品午夜免费不卡| 日韩人妻精品一区二区三区视频| 三级理论中文字幕在线播放| 国产萌白酱喷水视频在线观看| 午夜精品一区二区三区的区别| 丝袜无码一区二区三区| 97无码免费人妻超级碰碰碰碰| 少妇久久久久久被弄高潮| 女人被狂躁c到高潮视频| 又黄又硬又湿又刺激视频免费 | 国产欧美成人一区二区a片| 999国内精品永久免费视频| 国产97公开成人免费视频在线观看| 亚洲成成品网站源码中国有限公司| 精品无码久久久久久久久久| 成人aa免费视频在线播放| 国内精品乱码卡一卡2卡三卡新区| 国内极度色诱视频网站| 无码乱人伦一区二区亚洲一| 国产香蕉尹人在线视频你懂的| 亚洲不卡1卡2卡三卡入口| 国产色爱av资源综合区| 黑人好猛厉害爽受不了好大撑| 国产八十老太另类| 夜夜欢天天干| 蜜臀av午夜一区二区三区| 久久亚洲精品无码gv| 中文字幕乱码在线人视频| 后入到高潮免费观看| 欧美日韩精品一区二区视频| 成人一区二区免费中文字幕视频 |