在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATAD5 Antibody

ATAD5 Antibody

  • 中文名稱：
    ATAD5兔多克隆抗體
  • 貨號：
    CSB-PA052246
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: CSB-PA052246(ATAD5 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ATAD5
  • 別名：
    ATAD5 antibody; ATAD5_HUMAN antibody; ATPase family AAA domain containing 5 antibody; ATPase family AAA domain-containing protein 5 antibody; C17orf41 antibody; chromosome fragility associated gene 1 antibody; Chromosome fragility-associated gene 1 protein antibody; ELG1 antibody; Enhanced level of genomic instability 1 homolog antibody; FRAG1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human ATAD5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
  • 基因功能參考文獻：
    1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma. PMID: 27045477
    2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
    3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA levels on chromatin, thereby acting as a PCNA unloading factor. PMID: 23937667
    4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity. PMID: 23277426
    5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
    6. Studies indicate that USP1 and ELG1 as regulators of PCNA ubiquitylation. PMID: 21640107
    7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci. PMID: 19755857
    8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. PMID: 15983387

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數據庫鏈接：

    HGNC: 25752

    OMIM: 609534

    KEGG: hsa:79915

    STRING: 9606.ENSP00000313171

    UniGene: Hs.528902



主站蜘蛛池模板： 免费人成网站在线观看欧美| 亚洲日韩国产成网在线观看| 各处沟厕大尺度偷拍女厕嘘嘘| 中文字幕日产熟女乱码| 久久亚洲精品人成综合网| 天天躁日日躁aaaaxxxx| 日本三级欧美三级人妇视频黑白配| 免费视频爱爱太爽了激情| 性一交一乱一伦一| 少妇愉情理伦片bd| 丰满人妻熟妇乱又伦精品软件 | 两个男人吮她的花蒂和奶水视频| 国产色无码精品视频免费| 噜妇插内射精品| 无码专区—va亚洲v天堂麻豆| 国产性夜夜春夜夜爽免费下载| 丰满人妻精品国产99aⅴ| 国产日韩精品一区二区三区在线| 制服 丝袜 亚洲 中文 综合| 国产成人综合久久免费| 国产精品成人99一区无码| 亚洲乱亚洲乱少妇无码| 欧美处交wwwvideos另类| av 日韩 人妻 黑人 综合 无码| 国内老熟妇对白hdxxxx| 人妻少妇-嫩草影院| 精品国产午夜福利精品推荐| 熟妇人妻中文字幕| 人人妻一区二区三区| 日本护士xxxxhd少妇| 激情综合一区二区三区| 99e久热只有精品8在线直播| 卡1卡2卡3精品接入口| 亚洲伊人成综合网2222| 欧美xxxx精品另类| 2020最新国产高清毛片| 欧美精品亚洲精品日韩专区一乛方| 无遮挡又黄又刺激的视频| 三级久久试看3分钟| 国产免费二卡3卡四卡| 国产亚洲精品久久久久蜜臀|