在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ATP-dependent RNA helicase DDX39A (DDX39A)

  • 中文名稱:
    Recombinant Human ATP-dependent RNA helicase DDX39A(DDX39A)
  • 貨號:
    CSB-YP006620HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human ATP-dependent RNA helicase DDX39A(DDX39A)
  • 貨號:
    CSB-EP006620HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human ATP-dependent RNA helicase DDX39A(DDX39A)
  • 貨號:
    CSB-BP006620HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human ATP-dependent RNA helicase DDX39A(DDX39A)
  • 貨號:
    CSB-MP006620HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DDX39A
  • Uniprot No.:
  • 別名:
    DDX39A; DDX39; ATP-dependent RNA helicase DDX39A; EC 3.6.4.13; DEAD box protein 39; Nuclear RNA helicase URH49
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    2-427
  • 氨基酸序列
    AEQDVENDL LDYDEEEEPQ APQESTPAPP KKDIKGSYVS IHSSGFRDFL LKPELLRAIV DCGFEHPSEV QHECIPQAIL GMDVLCQAKS GMGKTAVFVL ATLQQIEPVN GQVTVLVMCH TRELAFQISK EYERFSKYMP SVKVSVFFGG LSIKKDEEVL KKNCPHVVVG TPGRILALVR NRSFSLKNVK HFVLDECDKM LEQLDMRRDV QEIFRLTPHE KQCMMFSATL SKDIRPVCRK FMQDPMEVFV DDETKLTLHG LQQYYVKLKD SEKNRKLFDL LDVLEFNQVI IFVKSVQRCM ALAQLLVEQN FPAIAIHRGM AQEERLSRYQ QFKDFQRRIL VATNLFGRGM DIERVNIVFN YDMPEDSDTY LHRVARAGRF GTKGLAITFV SDENDAKILN DVQDRFEVNV AELPEEIDIS TYIEQSR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus.
  • 基因功能參考文獻:
    1. DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation PMID: 28025139
    2. DDX39A is a potential biomarker for unfavorable neuroblastoma PMID: 26469522
    3. The protein levels of DDX39 were found to be higher in malignant pleural mesothelioma cell lines compared to normal pleural mesothelial cells. PMID: 23749908
    4. Results suggest that DDX39 is a suppressor of invasion and loss of its function predicts disease progression in bladder cancers. PMID: 22494014
    5. #NAME? PMID: 22119546
    6. Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection PMID: 21388492
    7. UAP56 and URH49 exhibit an intrinsic CRM1-independent nucleocytoplasmic shuttling PMID: 21799930
    8. Mx proteins exert their antiviral activity against IAV by interfering with the function of the RNA helicases UAP56 and URH49 PMID: 21859714
    9. Data show that the two closely related RNA helicases UAP56 and URH49 have evolved to form distinct mRNA export machineries, which regulate mitosis at different steps. PMID: 20573985
    10. Using a UL69 viral mutant that is unable to bind UAP56 and URH49, the authors demonstrated that UL69's interaction with UAP56 or URH49 does not contribute to the growth phenotype associated with the UL69 deletion mutant. PMID: 20610707
    11. Regulation of URH49 mRNA expression and comparison with the related UAP56 RNA helicase. PMID: 15047853
    12. Reducing the expression of UAP56 and URH49 resulted in a reduction in reporter gene expression as well as cell death within 72 h suggest that both helicases have essential but largely overlapping functions in the processing and export of mammalian mRNAs. PMID: 16949217
    13. CIP29 physically and functionally associates with DDX39, suggesting their cooperation in the RNA metabolism. PMID: 17196963
    14. DDX39 is a novel RNA helicase capable of promoting cancer cell growth PMID: 17548965

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
  • 蛋白家族:
    DEAD box helicase family, DECD subfamily
  • 組織特異性:
    Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland.
  • 數據庫鏈接:

    HGNC: 17821

    KEGG: hsa:10212

    STRING: 9606.ENSP00000242776

    UniGene: Hs.311609



主站蜘蛛池模板: 亚洲中文无码mv| 四虎一区二区成人免费影院网址| 99j久久精品久久久久久| 乱人伦视频中文字幕| 欧美黑人激情性久久| 熟妇人妻中文字幕| 亚洲精品成人a在线观看| 黑人尾随强伦姧人妻爽翻天| 日本一道高清一区二区三区| 亚洲一区二区三区偷拍女厕| 无码一区二区波多野结衣播放搜索| 麻花豆传媒剧国产免费mv入口| 亚州中文字幕无码中文字幕 | 用舌头去添高潮无码视频| 日韩精品人妻中文字幕有码| 真人做人60分钟啪啪免费看| 国产无遮挡a片又黄又爽漫画| 人人妻人人澡人人爽欧美一区双| 天天爽夜夜爽夜夜爽精品视频| 青青草国产精品欧美成人| 精品无码国产自产在线观看水浒传 | a∨变态另类天堂无码专区| 少妇呻吟白浆高潮啪啪69| 欧美日韩中文国产一区发布| 日本肉体xxxx裸交| 国产午夜无码片免费| 色在线亚洲视频www| 无码国产色欲xxxx视频| 无码av免费永久免费永久专区| 国产片免费福利片永久| 精品人妻系列无码一区二区三区| 一本无码人妻在中文字幕免费| 人妻av中文字幕一区二区三区 | 一区二区三区内射美女毛片| 欧美激情一区二区三区高清视频| 亚洲欧美综合精品成人网| 欧美肥老太交性506070| 艳妇乳肉豪妇荡乳xxx| 亚洲精品日本一区二区三区| 亚洲日韩成人无码不卡网站| 精品久久久无码人妻字幂|