在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ATP-dependent 6-phosphofructokinase, platelet type (PFKP PFKF)

  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-YP017823HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-EP017823HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-EP017823HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-BP017823HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-MP017823HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PFKAP
  • Uniprot No.:
  • 別名:
    ATP-dependent 6-phosphofructokinase, platelet type; ATP-PFK; PFK-P; EC 2.7.1.11; 6-phosphofructokinase type C; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphohexokinase; PFKP PFKF
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  • 基因功能參考文獻(xiàn):
    1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress. PMID: 28176759
    2. Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386. PMID: 29038421
    3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents. PMID: 27049827
    4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues. PMID: 26205495
    5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells. PMID: 24331211
    6. expression of TARDBP is significantly elevated in HCC and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR-520s). PMID: 23389994
    7. KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells. PMID: 21586797
    8. PFKP was identified using a trifunctional phenyl sulfonate probe. PMID: 12438565
    9. The transcription start point was determined at 48 bp upstream of the start codon. the region -65 to +48 turned out to be sufficient for promoter activity PMID: 15716112
    10. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population. PMID: 18682847

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm.
  • 蛋白家族:
    Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 8878

    OMIM: 171840

    KEGG: hsa:5214

    STRING: 9606.ENSP00000370517

    UniGene: Hs.26010



主站蜘蛛池模板: 久久本色成人综合网| 菠萝蜜视频在线观看入口| 久久99精品国产99久久6尤物| 日韩av无码社区一区二区三区| 久久久国产99久久国产久一| 真人作爱90分钟免费看视频| 久久精品噜噜噜成人| 精品国产经典三级在线看| 色老头av亚洲一区二区男男| av片日韩一区二区三区在线观看 | 日本夜爽爽一区二区三区| 欧美午夜精品久久久久久浪潮 | 国语自产拍在线视频中文| 国产 日韩 中文字幕 制服| 国产精品无码aⅴ嫩草| 女人18毛片水真多| 大桥未久亚洲一区二区| 开心色怡人综合网站| 国模杨依粉嫩蝴蝶150p | 内射中出日韩无国产剧情| 国产精品被窝福利一区| 亚洲丁香五月激情综合| 日本精品aⅴ一区二区三区| 国产特级毛片aaaaaa高潮流水| 韩国三级中文字幕hd久久精品| 春药玩弄少妇高潮吼叫| 在线天堂资源www中文| 国产伦孑沙发午休精品| 亚洲精品久久7777777| 国产精品视频一区二区亚瑟| 无线乱码一二三区免费看| 国产成人精品aa毛片| 艳妇臀荡乳欲伦69调教视频| 亚洲成a人片在线播放| 国产精品青草久久福利不卡| 高级会所人妻互换94部分| 国产色播av在线观看| 97se亚洲精品一区二区 | 午夜肉伦伦影院| 早起邻居人妻奶罩太松av | 国产偷窥盗摄一区二区|