在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PFKP Antibody

  • 中文名稱:
    PFKP兔多克隆抗體
  • 貨號:
    CSB-PA912667
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA912667(PFKP Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    1200015H23Rik antibody; 6 phosphofructokinase type C antibody; 6 phosphofructokinase, platelet type antibody; 6-phosphofructokinase antibody; 6-phosphofructokinase type C antibody; 9330125N24Rik antibody; FLJ40226 antibody; K6PP antibody; K6PP_HUMAN antibody; MGC105718 antibody; PFK C antibody; PFK, fibroblast type antibody; PFK-C antibody; PFKF antibody; PFKP antibody; Phosphofructo 1 kinase isozyme C antibody; Phosphofructo-1-kinase isozyme C antibody; Phosphofructokinase 1 antibody; Phosphofructokinase platelet antibody; Phosphohexokinase antibody; platelet type antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human PFKP
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  • 基因功能參考文獻:
    1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress. PMID: 28176759
    2. Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386. PMID: 29038421
    3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents. PMID: 27049827
    4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues. PMID: 26205495
    5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells. PMID: 24331211
    6. expression of TARDBP is significantly elevated in HCC and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR-520s). PMID: 23389994
    7. KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells. PMID: 21586797
    8. PFKP was identified using a trifunctional phenyl sulfonate probe. PMID: 12438565
    9. The transcription start point was determined at 48 bp upstream of the start codon. the region -65 to +48 turned out to be sufficient for promoter activity PMID: 15716112
    10. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population. PMID: 18682847

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
  • 數據庫鏈接:

    HGNC: 8878

    OMIM: 171840

    KEGG: hsa:5214

    STRING: 9606.ENSP00000370517

    UniGene: Hs.26010



主站蜘蛛池模板: 国产在线视频天天综合网| 中文天堂在线www| 图片区小说区激情区偷拍区| 亚洲 欧美 日产 综合 在线| 99热久久精里都是精品6| 天天av天天翘天天综合网| 亚洲日韩av无码中文字幕美国| 久久综合九色综合欧美就去吻| 天下第一社区视频www日本| 强行无套内谢大学生初次| 中文字幕无码视频专区| 影音先锋在线亚洲网站| 久久久亚洲精品av无码| 精品无人码麻豆乱码1区2区| 无码欧精品亚洲日韩一区| 国产成人综合亚洲精品| 99大香伊乱码一区二区| 国内精品人妻无码久久久影院蜜桃| 乱子轮熟睡1区| 乱人伦视频中文字幕| 日本一卡二卡四卡无卡国产| 狼人无码精华av午夜精品| 欧美18精品久久久无码午夜福利| 日本老熟妇乱子伦视频| 国产精品久久久久久久久久红粉 | 亚在线第一国产州精品99| 亚洲人成在线观看网站无码| 一区二区视频| 亚洲精品专区在线观看| 一本无码中文字幕在线观| 九九热爱视频精品视频| 米奇影视第四色| 又爽又黄又无遮挡的激情视频免费| 97无码免费人妻超级碰碰碰碰| 国产精品美女久久久久av超清| 成年女人18级毛片毛片免费| 亚洲精品欧美综合一区二区| 国产亚洲综合久久系列| 无码人妻精品一区二区三区在线| 高清破外女出血av毛片| 久久一卡二卡三卡四卡|