在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PFKP Antibody

  • 中文名稱:
    PFKP兔多克隆抗體
  • 貨號:
    CSB-PA082915
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from COS-7 cells and A549 cells, using K6PP antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PFKP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human K6PP.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  • 基因功能參考文獻:
    1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress. PMID: 28176759
    2. Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386. PMID: 29038421
    3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents. PMID: 27049827
    4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues. PMID: 26205495
    5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells. PMID: 24331211
    6. expression of TARDBP is significantly elevated in HCC and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR-520s). PMID: 23389994
    7. KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells. PMID: 21586797
    8. PFKP was identified using a trifunctional phenyl sulfonate probe. PMID: 12438565
    9. The transcription start point was determined at 48 bp upstream of the start codon. the region -65 to +48 turned out to be sufficient for promoter activity PMID: 15716112
    10. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population. PMID: 18682847

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
  • 數據庫鏈接:

    HGNC: 8878

    OMIM: 171840

    KEGG: hsa:5214

    STRING: 9606.ENSP00000370517

    UniGene: Hs.26010



主站蜘蛛池模板: 国产亚洲精品久久久网站好莱 | 免费无码午夜福利片| 亚洲欧美日韩国产综合v| 国产精品国产三级国av| 一級特黃色毛片免費看| 国产色婷婷亚洲99精品小说| 婷婷无套内射影院| 亚洲中文字幕av不卡无码| 永久免费无码av在线网站| 成人一区二区免费视频| 亚洲第一女人av| 国产乱码免费卡1卡二卡3| 亚洲精品乱码一区二区三区| 无码毛片一区二区本码视频| 大桥久未无码吹潮在线观看 | 一本久道久久综合狠狠老 | 亚洲裸男gv网站| 亚洲国产精品成人久久| 久久99久久99精品中文字幕| 日韩精品一区二区av在线| 欧美性猛交内射兽交老熟妇| 亚洲成在人线视av| 在线不卡日本v二区到六区| 中文日产幕无线码6区收藏| 成人无码精品1区2区3区免费看| 四虎亚洲中文字幕无码永久 | 国产又色又爽又刺激在线观看| 天码av无码一区二区三区四区| 国产亚洲中文日本不卡二区| 欧美成人高清视频a在线看| 亚洲国产精品第一区二区| 无码人妻丰满熟妇区五十路| 色综合天天天天综合狠狠爱| 粗大猛烈进出高潮视频| 香港aa三级久久三级| 少妇精品导航| 92午夜少妇极品福利无码电影| 国产在线观看www污污污| 欧美大成色www永久网站婷| 久久久亚洲欧洲日产国码αv| 最近日本精品一卡2卡3卡4卡 |