在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human AKT-interacting protein (AKTIP)

  • 中文名稱:
    Recombinant Human AKT-interacting protein(AKTIP)
  • 貨號:
    CSB-YP862043HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human AKT-interacting protein(AKTIP)
  • 貨號:
    CSB-EP862043HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human AKT-interacting protein(AKTIP)
  • 貨號:
    CSB-BP862043HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human AKT-interacting protein(AKTIP)
  • 貨號:
    CSB-MP862043HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    AKTIP
  • Uniprot No.:
  • 別名:
    AKT interacting protein; AKT-interacting protein; AKTIP; AKTIP_HUMAN; FT 1; FT1; Fused toes homolog; Fused toes protein homolog
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-292
  • 氨基酸序列
    MNPFWSMSTS SVRKRSEGEE KTLTGDVKTS PPRTAPKKQL PSIPKNALPI TKPTSPAPAA QSTNGTHASY GPFYLEYSLL AEFTLVVKQK LPGVYVQPSY RSALMWFGVI FIRHGLYQDG VFKFTVYIPD NYPDGDCPRL VFDIPVFHPL VDPTSGELDV KRAFAKWRRN HNHIWQVLMY ARRVFYKIDT ASPLNPEAAV LYEKDIQLFK SKVVDSVKVC TARLFDQPKI EDPYAISFSP WNPSVHDEAR EKMLTQKKPE EQHNKSVHVA GLSWVKPGSV QPFSKEEKTV AT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
  • 基因功能參考文獻:
    1. Results show that AKTIP co-purifies with A- and B-type lamins and partially co-localizes with lamins in interphase nuclei. In addition, AKTIP depletion lowers lamin A expression and induces senescence hallmarks including telomere homeostasis in human primary fibroblasts. PMID: 27512140
    2. results suggest that AKT1, FTO, and AKTIP polymorphisms were not associated with obesity/overweight in Brazilians children. PMID: 27342216
    3. FTS is involved in EGFR-mediated repair of DNA damage induced by cisplatin in ME180 cells PMID: 27535835
    4. AKTIP interacts with telomeric DNA and is required for telomere maintenance. PMID: 26110528
    5. High fused toes homolog expression is associated with radioresistance in cervical cancer. PMID: 25151576
    6. FTS silencing reduced EMT and cell migration by EGF treatment. These results demonstrate a novel function for FTS in EGF-mediated EMT process. PMID: 24971934
    7. *AKTIP single nucleotide polymorphisms are not associated with late-onset depression patients compared to healthy elderly controls. PMID: 24022875
    8. Targeted inhibition of FTS led to the shutdown of key elemental characteristics of cervical cancer and could lead to an effective therapeutic strategy. PMID: 21424602
    9. These data unraveled the involvement of new oncoprotein FTS in cervical cancer which plays a central role in carcinogenesis. PMID: 20945372
    10. Demographic and clinical characteristics and AKT1 single markers and haplotypes, but not AKTIP polymorphisms or interactions between AKT1 and AKTIP, are associated with increased risk for suicidal behavior in bipolar patients. PMID: 20132317
    11. Ft1 protein interacts directly with PKB, enhancing the phosphorylation of both of its regulatory sites by promoting its interaction with the upstream kinase PDK1 PMID: 14749367
    12. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex. PMID: 18799622

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell membrane; Peripheral membrane protein.
  • 蛋白家族:
    Ubiquitin-conjugating enzyme family, FTS subfamily
  • 數據庫鏈接:

    HGNC: 16710

    OMIM: 608483

    KEGG: hsa:64400

    STRING: 9606.ENSP00000378152

    UniGene: Hs.380897



主站蜘蛛池模板: 精品亚洲卡一卡2卡三卡乱码| 97精品一区二区视频在线观看| 成人区精品一区二区婷婷| 久久天堂av综合合色蜜桃网| 女人19水真多免费毛片| 久久久亚洲精品一区二区三区浴池| 欧美国产国产综合视频| 亚洲中文字幕永久在线不卡| 一区二区三区四区在线 | 欧洲| 亚洲色无码中文字幕yy51999| av片在线观看免费| 欧洲一卡2卡3卡4卡国产| 精品亚洲aⅴ在线无码播放| 欧美va天堂在线电影| 伊人色综合久久天天| 国产精品特黄aaaa片在线观看| 三级三级久久三级久久 | 日本护士毛茸茸| 日本三级韩国三级欧美三级| 国产精自产拍在线看中文| 亚洲人精品亚洲人成在线 | 久久久99久久久国产自输拍| 亚洲人av高清无码| 国产69囗曝吞精在线视频| 亚洲一线二线三线品牌精华液久久久 | 欧洲女人性开放免费网站| 国产女厕所盗摄老师厕所嘘嘘| 国产又粗又猛又黄又爽无遮挡 | 真人做受试看120分钟小视频| 在线成 人av影院| 久久综合狠狠综合久久综合88| 久久99精品国产99久久6尤物| av无码中文字幕不卡一区二区三区 | 寂寞人妻瑜伽被教练日| 牲交欧美兽交欧美| 女人被狂躁c到高潮视频| 日韩a毛片免费观看| 亚洲精品嫩草研究院久久| 久久久无码中文字幕久...| 国产成人乱色伦区| 国产自在自线午夜精品|