在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AKTIP Antibody

AKTIP Antibody

  • 中文名稱：
    AKTIP兔多克隆抗體
  • 貨號：
    CSB-PA862043ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA862043ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) AKTIP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AKTIP
  • 別名：
    AKT interacting protein antibody; AKT-interacting protein antibody; AKTIP antibody; AKTIP_HUMAN antibody; FT 1 antibody; FT1 antibody; Fused toes homolog antibody; Fused toes protein homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human AKT-interacting protein (1-292AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
  • 基因功能參考文獻：
    1. Results show that AKTIP co-purifies with A- and B-type lamins and partially co-localizes with lamins in interphase nuclei. In addition, AKTIP depletion lowers lamin A expression and induces senescence hallmarks including telomere homeostasis in human primary fibroblasts. PMID: 27512140
    2. results suggest that AKT1, FTO, and AKTIP polymorphisms were not associated with obesity/overweight in Brazilians children. PMID: 27342216
    3. FTS is involved in EGFR-mediated repair of DNA damage induced by cisplatin in ME180 cells PMID: 27535835
    4. AKTIP interacts with telomeric DNA and is required for telomere maintenance. PMID: 26110528
    5. High fused toes homolog expression is associated with radioresistance in cervical cancer. PMID: 25151576
    6. FTS silencing reduced EMT and cell migration by EGF treatment. These results demonstrate a novel function for FTS in EGF-mediated EMT process. PMID: 24971934
    7. *AKTIP single nucleotide polymorphisms are not associated with late-onset depression patients compared to healthy elderly controls. PMID: 24022875
    8. Targeted inhibition of FTS led to the shutdown of key elemental characteristics of cervical cancer and could lead to an effective therapeutic strategy. PMID: 21424602
    9. These data unraveled the involvement of new oncoprotein FTS in cervical cancer which plays a central role in carcinogenesis. PMID: 20945372
    10. Demographic and clinical characteristics and AKT1 single markers and haplotypes, but not AKTIP polymorphisms or interactions between AKT1 and AKTIP, are associated with increased risk for suicidal behavior in bipolar patients. PMID: 20132317
    11. Ft1 protein interacts directly with PKB, enhancing the phosphorylation of both of its regulatory sites by promoting its interaction with the upstream kinase PDK1 PMID: 14749367
    12. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex. PMID: 18799622

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family, FTS subfamily
  • 數據庫鏈接：

    HGNC: 16710

    OMIM: 608483

    KEGG: hsa:64400

    STRING: 9606.ENSP00000378152

    UniGene: Hs.380897



主站蜘蛛池模板： 四虎成人精品永久网站| 久久亚洲精品成人无码网站夜色| 久久99精品久久久久久2021| 天天躁人人躁人人躁狂躁| 国产乱人伦精品一区二区| 玩弄人妻少妇500系列网址| 国产主播一区二区三区在线观看| 末成年女av片一区二区| 久久国产欧美日韩精品| 亚洲不乱码卡一卡二卡4卡5卡| 亚洲爆乳成av人在线蜜芽| 成年无码a√片在线观看| 波多野结av衣东京热无码专区| 久久er热在这里只有精品66| 色欲来吧来吧天天综合网| 国产又爽又黄又无遮挡的激情视频 | 日韩av高清在线观看| 国产一区二区三区精品av| 久热在线播放中文字幕| 无码国产伦一区二区三区视频| 成片免费观看视频大全| 欧美最猛性xxxxx大叫| 国产国产精品人在线视| 国产成人无码网站| 日本高清一二三不卡区| 最新亚洲中文av在线不卡| 中文字幕人妻无码视频| 中文中幕a在线| 日产2021免费一区| 76少妇精品导航| 国产免费一区二区三区免费视频| 天堂√最新版中文在线天堂| 亚洲精品久久婷婷丁香51| 极品少妇被后入内射视| 国产粗话肉麻对白在线播放| 性色香蕉av久久久天天网| 2021无码最新国产在线观看| 国产在线精品一区二区夜色| 久久99精品国产免费观观| 大地资源网中文第五页| 亚洲暴爽av天天爽日日碰|