在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 59 kDa 2'-5'-oligoadenylate synthase-like protein (OASL)

  • 中文名稱:
    人OASL重組蛋白
  • 貨號:
    CSB-YP614897HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人OASL重組蛋白
  • 貨號:
    CSB-EP614897HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人OASL重組蛋白
  • 貨號:
    CSB-BP614897HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人OASL重組蛋白
  • 貨號:
    CSB-MP614897HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    OASL
  • Uniprot No.:
  • 別名:
    2' 5' oligoadenylate synthetase like; 2''-5''-OAS-related protein; 2''-5''-OAS-RP; 2''-5''-oligoadenylate synthase-like protein; 2'-5' oligoadenylate synthetase-like 2; 2'-5'-oligoadenylate synthetase-like; 59 kDa 2' 5' oligoadenylate synthetase like protein; 59 kDa 2''-5''-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; M1204; Mmu-OASL; OASL; OASL_HUMAN; Oasl2; p59 OASL; p59OASL; THYROID HORMONE RECEPTOR INTERACTOR 14; Thyroid receptor interacting protein 14; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP-14; TRIP14
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-514
  • 氨基酸序列
    ALMQELYST PASRLDSFVA QWLQPHREWK EEVLDAVRTV EEFLRQEHFQ GKRGLDQDVR VLKVVKVGSF GNGTVLRSTR EVELVAFLSC FHSFQEAAKH HKDVLRLIWK TMWQSQDLLD LGLEDLRMEQ RVPDALVFTI QTRGTAEPIT VTIVPAYRAL GPSLPNSQPP PEVYVSLIKA CGGPGNFCPS FSELQRNFVK HRPTKLKSLL RLVKHWYQQY VKARSPRANL PPLYALELLT IYAWEMGTEE DENFMLDEGF TTVMDLLLEY EVICIYWTKY YTLHNAIIED CVRKQLKKER PIILDPADPT LNVAEGYRWD IVAQRASQCL KQDCCYDNRE NPISSWNVKR ARDIHLTVEQ RGYPDFNLIV NPYEPIRKVK EKIRRTRGYS GLQRLSFQVP GSERQLLSSR CSLAKYGIFS HTHIYLLETI PSEIQVFVKN PDGGSYAYAI NPNSFILGLK QQIEDQQGLP KKQQQLEFQG QVLQDWLGLG IYGIQDSDTL ILSKKKGEAL FPAS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • 基因功能參考文獻(xiàn):
    1. These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen. PMID: 27190175
    2. OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth. PMID: 26178980
    3. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes. PMID: 24328427
    4. these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I activation. PMID: 24931123
    5. we propose that VSV treatment combined with the selective regulation of genes such as STAT1 and OASL2 will improve therapeutic outcomes for CUG2-overexpressing tumors PMID: 23306614
    6. variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits PMID: 21943158
    7. The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein. PMID: 19203244
    8. The expression of OASL and IFIT2 was significantly higher in SLE patients than in controls. PMID: 20506645
    9. OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains. PMID: 20074559
    10. interaction with methyl CpG-binding protein 1 was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL PMID: 14728690
    11. Proof that OASL is an antiviral protein that works through a novel mechanism distinct from other OASL proteins in other vertebrate species. PMID: 18931074

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
  • 蛋白家族:
    2-5A synthase family
  • 組織特異性:
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 8090

    OMIM: 603281

    KEGG: hsa:8638

    STRING: 9606.ENSP00000257570

    UniGene: Hs.118633



主站蜘蛛池模板: 区二区三区玖玖玖| 亚洲一区二区三区含羞草| 国产极品视觉盛宴| 国产麻豆剧果冻传媒一区 | 英语老师丝袜娇喘好爽视频| 国产午夜精品av一区二区麻豆| 精品国产一区二区三区四区阿崩| 好吊妞无缓冲视频观看| 国产av国内精品jk制服| 亚洲色中文字幕在线播放| 少妇又紧又深又湿又爽视频| 久久av无码精品人妻系列| 97久久久人妻一区精品| 亚洲在av极品无码| 午夜无码国产理论在线| 日本护士毛茸茸| 久久99精品国产麻豆婷婷| 日韩精品无码人妻一区二区三区| 国产高潮流白浆视频| 五月天激情国产综合婷婷婷| 亚洲色成人网站www永久四虎| 最新69国产成人精品视频免费| 国产在线欧美日韩精品一区| 人妻三级日本香港三级极97| 夜夜高潮夜夜爽国产伦精品| 无码人妻一区二区三区免费n鬼沢| 婷婷丁香六月激情综合在线人| 被窝影院午夜无码国产| 最近中文av字幕在线中文| 国产蜜臀av在线一区尤物| 亚洲中文字幕无码永久| 青娱国产区在线| 国产偷国产偷亚洲清高app| 亚洲综合无码精品一区二区三区| 最新精品视频2019在线视频| 国产精品 中文字幕 亚洲 欧美 | 亚洲男人天堂| 精品久久国产字幕高潮| 国产自愉自愉免费精品七区 | 熟妇人妻无乱码中文字幕| 欧美xxxx做受欧美|