在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OASL Antibody

OASL Antibody

  • 中文名稱：
    OASL兔多克隆抗體
  • 貨號：
    CSB-PA925792
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA925792(OASL Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    OASL
  • 別名：
    2' 5' oligoadenylate synthetase like antibody; 2''-5''-OAS-related protein antibody; 2''-5''-OAS-RP antibody; 2''-5''-oligoadenylate synthase-like protein antibody; 2'-5' oligoadenylate synthetase-like 2 antibody; 2'-5'-oligoadenylate synthetase-like antibody; 59 kDa 2' 5' oligoadenylate synthetase like protein antibody; 59 kDa 2''-5''-oligoadenylate synthase-like protein antibody; 59 kDa 2'-5'-oligoadenylate synthetase-like protein antibody; M1204 antibody; Mmu-OASL antibody; OASL antibody; OASL_HUMAN antibody; Oasl2 antibody; p59 OASL antibody; p59OASL antibody; THYROID HORMONE RECEPTOR INTERACTOR 14 antibody; Thyroid receptor interacting protein 14 antibody; Thyroid receptor-interacting protein 14 antibody; TR-interacting protein 14 antibody; TRIP-14 antibody; TRIP14 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human OASL
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • 基因功能參考文獻：
    1. These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen. PMID: 27190175
    2. OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth. PMID: 26178980
    3. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes. PMID: 24328427
    4. these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I activation. PMID: 24931123
    5. we propose that VSV treatment combined with the selective regulation of genes such as STAT1 and OASL2 will improve therapeutic outcomes for CUG2-overexpressing tumors PMID: 23306614
    6. variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits PMID: 21943158
    7. The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein. PMID: 19203244
    8. The expression of OASL and IFIT2 was significantly higher in SLE patients than in controls. PMID: 20506645
    9. OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains. PMID: 20074559
    10. interaction with methyl CpG-binding protein 1 was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL PMID: 14728690
    11. Proof that OASL is an antiviral protein that works through a novel mechanism distinct from other OASL proteins in other vertebrate species. PMID: 18931074

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
  • 蛋白家族：
    2-5A synthase family
  • 組織特異性：
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • 數據庫鏈接：

    HGNC: 8090

    OMIM: 603281

    KEGG: hsa:8638

    STRING: 9606.ENSP00000257570

    UniGene: Hs.118633



主站蜘蛛池模板： 97精品久久久久中文字幕| 午夜无码人妻av大片色欲| 亚洲色成人中文字幕网站| 日日噜噜夜夜狠狠视频| 国产在线高清理伦片a| 国产片av国语在线观麻豆| 国产精品亚洲二区在线观看| 国产亚洲日韩欧美一区二区三区| 国产av国内精品jk制服| 久久99精品久久久久久久不卡| 欧美大屁股熟妇bbbbbb| 精品人妻大屁股白浆无码| 亚洲精品久久片久久久久| 国产精品极品在线拍| 一边摸一边抽搐一进一出视频| 亚欧成a人无码精品va片| 亚洲精品宾馆在线精品酒店| 人妻av无码中文专区久久| 中国女人内谢69xxxx视频| 亚洲偷自拍国综合| 亚洲а∨天堂久久精品| 在线精品视频一区二区三区| 久久久久国产精品人妻| 日本道精品一区二区三区| 国产婷婷综合在线视频| 蜜臀av在线播放一区二区三区| 天天爽夜夜爽夜夜爽| 97se狼狼狼狼狼亚洲网| 无码孕妇孕交在线观看| 国产精品国产免费无码专区不卡| 99久久无色码中文字幕人妻蜜柚| 狠狠噜天天噜日日噜视频跳一跳| 人妻精品无码一区二区三区 | 久久一本久综合久久爱| 亚洲成av人影院无码不卡| 少妇被躁爽到高潮无码久久| 亚洲一卡一卡二新区无人区| 亚洲天堂在线观看完整版| 国产又色又爽又高潮免费| 亚洲天堂2017无码| 小鲜肉洗澡时自慰网站xnxx|