在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. OASL Antibody

OASL Antibody

  • 中文名稱：
    OASL兔多克隆抗體
  • 貨號：
    CSB-PA661512
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HELA cells using primary antibody diluted at 1:2000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    OASL
  • 別名：
    2' 5' oligoadenylate synthetase like antibody; 2''-5''-OAS-related protein antibody; 2''-5''-OAS-RP antibody; 2''-5''-oligoadenylate synthase-like protein antibody; 2'-5' oligoadenylate synthetase-like 2 antibody; 2'-5'-oligoadenylate synthetase-like antibody; 59 kDa 2' 5' oligoadenylate synthetase like protein antibody; 59 kDa 2''-5''-oligoadenylate synthase-like protein antibody; 59 kDa 2'-5'-oligoadenylate synthetase-like protein antibody; M1204 antibody; Mmu-OASL antibody; OASL antibody; OASL_HUMAN antibody; Oasl2 antibody; p59 OASL antibody; p59OASL antibody; THYROID HORMONE RECEPTOR INTERACTOR 14 antibody; Thyroid receptor interacting protein 14 antibody; Thyroid receptor-interacting protein 14 antibody; TR-interacting protein 14 antibody; TRIP-14 antibody; TRIP14 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human OASL. at AA range: 1-50
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB,ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:10000-20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • 基因功能參考文獻：
    1. These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen. PMID: 27190175
    2. OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth. PMID: 26178980
    3. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes. PMID: 24328427
    4. these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I activation. PMID: 24931123
    5. we propose that VSV treatment combined with the selective regulation of genes such as STAT1 and OASL2 will improve therapeutic outcomes for CUG2-overexpressing tumors PMID: 23306614
    6. variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits PMID: 21943158
    7. The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein. PMID: 19203244
    8. The expression of OASL and IFIT2 was significantly higher in SLE patients than in controls. PMID: 20506645
    9. OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains. PMID: 20074559
    10. interaction with methyl CpG-binding protein 1 was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL PMID: 14728690
    11. Proof that OASL is an antiviral protein that works through a novel mechanism distinct from other OASL proteins in other vertebrate species. PMID: 18931074

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
  • 蛋白家族：
    2-5A synthase family
  • 組織特異性：
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • 數據庫鏈接：

    HGNC: 8090

    OMIM: 603281

    KEGG: hsa:8638

    STRING: 9606.ENSP00000257570

    UniGene: Hs.118633



主站蜘蛛池模板： 免费无码av一区二区三区| 欧美日韩人妻精品一区二区在线| 嫩草国产福利视频一区二区| 极品少妇小泬50pthepon| 久久这里只有精品18| 香蕉在线精品视频在线| 国产一卡2卡3卡四卡精品国色无边 | 欧美放荡的少妇| 无码福利一区二区三区| 一区二区三区波多野结衣在线观看| 免费无码又爽又刺激软件下载| 日韩人妻无码免费视频一区二区 | 亚洲熟少妇在线播放999| 久久精品国产成人午夜福利| 播放灌醉水嫩大学生国内精品| yy111111少妇无码理论片| 国内无遮挡18禁无码网站免费| 精品无码久久久久国产app| 国产乱人伦av麻豆网| 欧美高清精品一区二区| 少妇乳大丰满在线播放| 欧美熟妇性xxx交潮喷| 国产女人的高潮国语对白| 婷婷五月日韩av永久免费| 中文字幕久久精品无码| 成人精品视频99在线观看免费 | 久久午夜福利无码1000合集| 男男gv白嫩小受gv在线播放| 国产免费一区二区三区不卡| 波多野结衣一区二区三区av高清| 成人性生交大片免费看96| 成人av久久一区二区三区| 久久久久久人妻精品一区| 国语精品一区二区三区| 亚洲国产成在人网站天堂| 国产成人av在线一区二区三区| 久久精品国产丝袜人妻| 午夜理论在线观看不卡大地影院 | 日韩成人无码一区二区三区| 玩弄放荡人妇系列av在线网站 | 少妇精品久久久一区二区三区|