在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Suppressor of hairless protein (Su (H)), partial

Recombinant Drosophila melanogaster Suppressor of hairless protein (Su (H)), partial

  • 中文名稱：
    黑腹果蠅Su(H)重組蛋白
  • 貨號：
    CSB-YP328775DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Su(H)重組蛋白
  • 貨號：
    CSB-EP328775DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Su(H)重組蛋白
  • 貨號：
    CSB-EP328775DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Su(H)重組蛋白
  • 貨號：
    CSB-BP328775DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Su(H)重組蛋白
  • 貨號：
    CSB-MP328775DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Su(H)
  • Uniprot No.：
  • 別名：
    Su(H); dRBP-JK; CG3497; Suppressor of hairless protein; J kappa-recombination signal-binding protein; RBP-J kappa
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Required for transcription of Sim. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Required for neurogenesis in imaginal disks. In the larval brain, might play a role as a transducer of Notch signaling during type II neuroblast development. Also functions independently of the Notch pathway, in the development of the bristle sensory organ precursor cell.
  • 基因功能參考文獻：
    1. complex genetic interactions of novel alleles deficient in co-repressor binding PMID: 29509808
    2. Structural models show that the Hairless-Su(H) repressor complexes from Daphnia and Drosophila are almost indistinguishable from one another. Amino acid residues in direct contact within the Hairless-Su(H) complex are at absolutely identical positions in the two homologues. PMID: 28861687
    3. Su(H) protein levels depend on the interactions with H as well as with Notch. PMID: 28475577
    4. X-ray structure of the Su(H)-Hairless complex bound to DNA. PMID: 27404588
    5. The role of Su(H) in conferring chromatin characteristics at Notch-regulated enhancers PMID: 26069324
    6. the molecular cross talk at the level of Suppressor of Hairless [Su(H)], is reported. PMID: 25452105
    7. human RITA, binding to Drosophila Su(H) and tubulin, cannot influence the Notch signalling pathway in the fly PMID: 25588307
    8. Su(H) repression acts as a counterbalance to Dorsal- and Zelda-mediated activation. PMID: 25313963
    9. This study demonistrated that transcriptional activity of Su(H) in Notch signaling in the mushroom bodies is critical for the formation of long-term memory. PMID: 19863271
    10. the C-terminal domain of Su(H) is necessary and sufficient for forming a high-affinity complex with Hairless PMID: 21737682
    11. Su(H)-H complexes can bind to DNA with high efficiency in vitro. Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. PMID: 12154126
    12. Loss of Su(H) function leads to an arrest of sensory organ precursors development PMID: 12642500
    13. the accumulation of Notch (N) in the late-endosome was required for the deltex -mediated Su(H)-independent N signaling PMID: 15496440
    14. crucial roles for the adaptor protein Hairless in conferring repressive activity on Su(H) in the Drosophila sensory organ precursor. PMID: 15975935
    15. acts on identified regulatoru seq pf roughest gene PMID: 16096801
    16. Su(H) acts as a transcriptional repressor in the absence of a Notch signal and as a transcriptional activator in its presence in several developmental contexts. PMID: 16397895

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Su(H) family
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG3497

    STRING: 7227.FBpp0080261

    UniGene: Dm.2288



主站蜘蛛池模板： 正在播放的国产a一片| 久久综合狠狠综合久久综合88 | 亚洲日本在线电影| 国产黄a三级三级三级| 国产午夜福利在线观看红一片| 中文字幕人妻少妇引诱隔壁| 97人人添人澡人人爽超碰| 免费一区二区无码东京热| 在线观看国产一区二区三区 | 亚洲人成电影综合网站色www| 99久久国产综合精品成人影院 | 九九re6热在线视频精品66| 国产99久久久国产精品～～牛 | 无码人妻精品一区二区三区免费| 狠日狠干日日射| 亚洲午夜久久久影院伊人| 无码精品人妻一区二区三区人妻斩| 黑人巨大videos精品| 精品国产一区二区三区av 性色 | 熟女少妇在线视频播放| 国内午夜国产精品小视频| 高潮迭起av乳颜射后入| 欧洲乱码伦视频免费| 人妻免费一区二区三区最新| 末发育娇小性色xxxxx| 四虎精品免费永久免费视频| 97久久精品亚洲中文字幕无码| 人妻少妇邻居少妇好多水在线 | 国产精品天干在线观看| 成人区人妻精品一区二区三区| 国产精品久久毛片av大全日韩| 亚洲熟妇久久国内精品| 亚洲熟妇av综合网五月| 成人久久久久久久久久久| 成人性生交大片免费看vr| 成年免费视频播放网站推荐| av无码欧洲亚洲电影网| 又大又粗欧美黑人aaaaa片| 日韩av无码社区一区二区三区| 6080亚洲人久久精品| www国产亚洲精品|