在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Histone H2A.v (His2Av)

Recombinant Drosophila melanogaster Histone H2A.v (His2Av)

  • 中文名稱：
    黑腹果蠅His2Av重組蛋白
  • 貨號(hào)：
    CSB-YP010095DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅His2Av重組蛋白
  • 貨號(hào)：
    CSB-EP010095DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅His2Av重組蛋白
  • 貨號(hào)：
    CSB-EP010095DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅His2Av重組蛋白
  • 貨號(hào)：
    CSB-BP010095DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅His2Av重組蛋白
  • 貨號(hào)：
    CSB-MP010095DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    His2Av
  • Uniprot No.：
  • 別名：
    His2Av; H2AvD; His2AvD; CG5499; Histone H2A.v; H2A.F/Z; H2A.Z
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-141
  • 氨基酸序列
    AGGKAGKDS GKAKAKAVSR SARAGLQFPV GRIHRHLKSR TTSHGRVGAT AAVYSAAILE YLTAEVLELA GNASKDLKVK RITPRHLQLA IRGDEELDSL IKATIAGGGV IPHIHKSLIG KKEETVQDPQ RKGNVILSQA Y
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.
  • 基因功能參考文獻(xiàn)：
    1. H2Av or H3S10 phosphorylation by JIL-1 is not required for chromatin decondensation or transcriptional elongation in Drosophila. PMID: 28807902
    2. The nucleosome positioning sequence (NPS) patterns from H2A.Z nucleosomes differ from the NPS patterns from H2A nucleosomes. The purine-purine/pyrimidine-pyrimidine pattern of H2A.Z nucleosomes has major peaks shifted by 10 bp deviated from the H2A nucleosome pattern. The H2A and H2A.Z nucleosomes have different sequence preferences. PMID: 27992255
    3. the H2AZ-like rather than the H2AX-like function of H2AV is primarily required for normal hematopoiesis. PMID: 28242611
    4. The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation. PMID: 25591068
    5. nucleosomes present significant, context-specific barriers to RNAPII in vivo that can be tuned by the incorporation of H2A.Z PMID: 24606920
    6. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av in a nucleosome positioned in promoter regions of PARP-1-dependent genes PMID: 24508391
    7. Unlike other organisms that employ several H2A variants for different functions, the parsimonious fruit fly Drosophila melanogaster gets along with just a single H2A variant, H2A.V. Remarkably, H2A.V unites within one molecule features and functions of two different mammalian H2A variants, H2A.Z and H2A.X. [Review] PMID: 23553272
    8. H2A.Z nucleosome occupancy has no effect on sequence variability of Drosophila genome PMID: 23472174
    9. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av). PMID: 21444826
    10. in the absence of H2A.Z, checkpoint-defective telomeres adopt alternative structures, which are permissive for the loading of the capping machinery at Drosophila telomeres. PMID: 18845840

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Chromosome. Note=Widely distributed in the genome, irrespective of the transcriptional status or coding capacity of the sequence.
  • 蛋白家族：
    Histone H2A family
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG5499

    STRING: 7227.FBpp0084434

    UniGene: Dm.2346



主站蜘蛛池模板： 国产丝袜肉丝视频在线| 亚洲欧洲成人a∨在线| 性欧美大战久久久久久久| 精品一区二区三区免费毛片爱| 久久久久香蕉国产线看观看伊 | 一区二区久久久久草草| 日韩免费无砖专区2020狼 | 大地资源网第二页免费观看 | 亚洲精品无码永久在线观看性色 | 少妇愉情理伦片bd| 色吊丝av中文字幕| 免费1级a做爰片观看| 真实国产乱子伦在线视频| 欧美搡bbbbb搡bbbbb| 强奷乱码中文字幕熟女导航| 女人被弄到高潮的免费视频 | 精品一区二区三区无码免费视频| 国产午夜精华2020在线| 国产欧美日本亚洲精品一5区| 国产麻豆一精品一av一免费| 无码人妻一区二区三区免费| 日韩av一国产av一中文字慕| 人人爽人人爽人人片a免费| 国产精品久久久久久久久久红粉| 97精品一区二区视频在线观看| 精品久久久久久久久午夜福利| 9lporm自拍视频区| 国产av丝袜旗袍无码网站| 色爱情人网站| 国产成人18黄网站在线观看| 欧美三级午夜理伦三级| 成年丰满熟妇午夜免费视频| 熟睡中被义子侵犯在线播放| 一边摸一边叫床一边爽av| 国产乱子伦农村xxxx| 国产精品igao视频网| 乌克兰性欧美精品高清| 美女内射毛片在线看3d| 天堂av男人在线播放| 久久人人爽av亚洲精品| 久久久精品人妻一区二区三区蜜桃 |