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  4. Recombinant Drosophila melanogaster Cytochrome P450 6g1 (Cyp6g1), partial

Recombinant Drosophila melanogaster Cytochrome P450 6g1 (Cyp6g1), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Cytochrome P450 6g1(Cyp6g1) ,partial
  • 貨號：
    CSB-YP894648DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Cytochrome P450 6g1(Cyp6g1) ,partial
  • 貨號：
    CSB-EP894648DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Cytochrome P450 6g1(Cyp6g1) ,partial
  • 貨號：
    CSB-EP894648DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Cytochrome P450 6g1(Cyp6g1) ,partial
  • 貨號：
    CSB-BP894648DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Cytochrome P450 6g1(Cyp6g1) ,partial
  • 貨號：
    CSB-MP894648DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Cyp6g1
  • Uniprot No.：
  • 別名：
    Cyp6g1; CYP6-like; DDT-R; Rst(2)DDT; CG8453Cytochrome P450 6g1; EC 1.14.-.-; CYPVIG1; Cyp6-like protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Necessary and sufficient for resistance to insecticides DDT and imidacloprid. May be involved in the metabolism of insect hormones.
  • 基因功能參考文獻：
    1. CYP6g1 role in the azinphos-methyl resistance PMID: 27317781
    2. a combination of gene duplication, regulatory changes and protein coding changes has taken place at the Cyp6g1 locus during evolution and this locus may play a role in providing resistance to different environmental toxins in different Drosophila species PMID: 24416303
    3. Recombinant D. melanogaster CYP6G1 exhibited p-nitroanisole O-dealkylation activity but was not active against eleven other typical P450 marker substrates. PMID: 23470655
    4. expression and tolerance to methylmercury during development PMID: 22699155
    5. Resistance to nicotine or related plant allelochemicals is one of the beneficial phenotypes conferred by the Accord insertion allele of CYP6G1. PMID: 22543020
    6. The induction response of the P450 gene Cyp6g1 to the xenobiotic phenobarbital requires the presence of both tissue specific enhancers and a distinct cis-regulatory element. PMID: 21807095
    7. The active site of Cyp6g1 can accommodate differently shaped substrates. PMID: 20583201
    8. Cyp6g1 locus is a major contributor to Dichloro-Diphenyl-Trichloroethane resistance in field populations PMID: 20585622
    9. Caffeine, DDT and phenobarbital fail to induce upstream DNAs of Cyp6g1. PMID: 20002224
    10. results show that DDT-R, a gene conferring resistance to DDT, is associated with overtranscription of a single cytochrome P450 gene, Cyp6g1 PMID: 12351787
    11. Data show that Cyp6g1 itself may not have to be overexpressed for DDT resistance to occur. PMID: 17134855
    12. Cis-regulatory elements in the accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1. PMID: 17179088
    13. when levels of Cyp6g1 gene were manipulated in just the Malpighian tubules of adult Drosophila, the survival of the whole insect after 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) challenge was altered. PMID: 17488889
    14. CYP6G1 is capable of metabolising at least two insecticides. PMID: 17912692

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  • 亞細胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG8453

    STRING: 7227.FBpp0087100

    UniGene: Dm.3866



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