在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Dog cAMP-dependent protein kinase catalytic subunit alpha (PRKACA)

  • 中文名稱:
    熟悉的犬PRKACA重組蛋白
  • 貨號:
    CSB-YP822648DO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    熟悉的犬PRKACA重組蛋白
  • 貨號:
    CSB-EP822648DO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    熟悉的犬PRKACA重組蛋白
  • 貨號:
    CSB-BP822648DO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    熟悉的犬PRKACA重組蛋白
  • 貨號:
    CSB-MP822648DO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PRKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; EC 2.7.11.11
  • 種屬:
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-350
  • 氨基酸序列
    GNAAAKKGS EQESVKEFLA KAKEDFLKKW ENPAQNTAHL DQFERIKTLG TGSFGRVMLV KHKETGNHFA MKILDKQKVV KLKQIEHTLN EKRILQAVNF PFLVKLEFSF KDNSNLYMVM EYVPGGEMFS HLRRIGRFSE PHARFYAAQI VLTFEYLHSL DLIYRDLKPE NLLIDQQGYI QVTDFGFAKR VKGRTWTLCG TPEYLAPEII LSKGYNKAVD WWALGVLIYE MAAGYPPFFA DQPIQIYEKI VSGKVRFPSH FSSDLKDLLR NLLQVDLTKR FGNLKNGVND IKNHKWFATT DWIAIYQRKV EAPFIPKFKG PGDTSNFDDY EEEEIRVSIN EKCGKEFCEF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA, SOX9 and VASP. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in chondrogenesis by mediating phosphorylation of SOX9. Involved in the regulation of platelets in response to thrombin and collagen; maintains circulating platelets in a resting state by phosphorylating proteins in numerous platelet inhibitory pathways when in complex with NF-kappa-B (NFKB1 and NFKB2) and I-kappa-B-alpha (NFKBIA), but thrombin and collagen disrupt these complexes and free active PRKACA stimulates platelets and leads to platelet aggregation by phosphorylating VASP. RYR2 channel activity is potentiated by phosphorylation in presence of luminal Ca(2+), leading to reduced amplitude and increased frequency of store overload-induced Ca(2+) release (SOICR) characterized by an increased rate of Ca(2+) release and propagation velocity of spontaneous Ca(2+) waves, despite reduced wave amplitude and resting cytosolic Ca(2+). PSMC5/RPT6 activation by phosphorylation stimulates proteasome. Negatively regulates tight junctions (TJs) in ovarian cancer cells via CLDN3 phosphorylation. NFKB1 phosphorylation promotes NF-kappa-B p50-p50 DNA binding. Involved in embryonic development by down-regulating the Hedgehog (Hh) signaling pathway that determines embryo pattern formation and morphogenesis. Prevents meiosis resumption in prophase-arrested oocytes via CDC25B inactivation by phosphorylation. May also regulate rapid eye movement (REM) sleep in the pedunculopontine tegmental (PPT). Phosphorylates APOBEC3G and AICDA. Phosphorylates HSF1; this phosphorylation promotes HSF1 nuclear localization and transcriptional activity upon heat shock.
  • 基因功能參考文獻:
    1. PKA rapidly enhances proteasome assembly and activity in in vivo hearts. PMID: 19059265
  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane. Mitochondrion. Membrane; Lipid-anchor. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族:
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily
  • 組織特異性:
    Ubiquitously expressed in mammalian tissues.
  • 數據庫鏈接:

    KEGG: cfa:403556

    STRING: 9615.ENSCAFP00000024262

    UniGene: Cfa.74



主站蜘蛛池模板: 日韩欧群交p片内射中文| 五月综合色婷婷在线观看| 天天爽天天狠久久久综合麻豆| 亚洲v天堂v手机在线| 国产亚洲视频中文字幕97精品| 日韩av高清无码| 日韩av毛片无码免费| 中文字幕av无码专区第一页| 日韩大片高清播放器| 亚洲乱码国产乱码精品精大量 | 国产成人精品a视频免费福利| 欧美另类videossexo高潮| 日本高清视频www夜色资源| 日本特黄aaaaaa片在线观看| av性色av久久无码ai换脸| 成人综合婷婷国产精品久久蜜臀| 九月婷婷人人澡人人添人人爽 | 妇女性内射冈站hdwww000| 天天爱天天做久久狠狠做| 成人亚洲国产精品一区不卡| 妲己丰满人熟妇大尺度人体艺| 久久久久久国产精品免费免费| 国产成人久久精品一区二区三区 | 在线播放偷拍一区精品| 国模吧无码一区二区三区| 丝袜人妻一区二区三区| 国产日产亚洲系列最新美使用方法 | 久久草莓香蕉频线观| 精品亚洲麻豆1区2区3区| 肉体裸交丰满丰满少妇在线观看| 香蕉啪视频在线观看视频久| 在线观看午夜亚洲一区| 国模叶桐尿喷337p人体| 无翼乌工口全彩肉肉无遮挡18| 久久久噜噜噜久久熟女色| 欧美疯狂xxxxbbbb喷潮| 欧美国产国产综合视频| 免费无码黄动漫十八禁| 国产欧美亚洲日韩图片| 搡8o老女人老妇人老熟| 骚女人干起来舒服视频在线|