在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Zinc finger RAD18 domain-containing protein C1orf124 homolog

Recombinant Bovine Zinc finger RAD18 domain-containing protein C1orf124 homolog

  • 中文名稱：
    牛SPRTN重組蛋白
  • 貨號：
    CSB-YP399770BO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SPRTN重組蛋白
  • 貨號：
    CSB-EP399770BO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SPRTN重組蛋白
  • 貨號：
    CSB-EP399770BO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SPRTN重組蛋白
  • 貨號：
    CSB-BP399770BO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SPRTN重組蛋白
  • 貨號：
    CSB-MP399770BO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SPRTN
  • Uniprot No.：
  • 別名：
    SPRTN; SprT-like domain-containing protein Spartan; Protein with SprT-like domain at the N terminus; Spartan
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-487
  • 氨基酸序列
    MDEDLVLALQ LQEEWNLQVS EREPAQEPLS LVDASWELVD PTPDLQGLFV LFNDRFFWGQ LEAVEVKWSV RMTLCAGICS YEGRGGMCSI RLSEPLLKLR PRKDLVETLL HEMIHAYLFV TNNDKDREGH GPEFCKHMHR INRLTGANIT VYHTFHDEVD EYRRHWWRCN GPCQNSKPYY GYVKRATNRA PSAHDYWWAE HQKTCGGTYI KIKEPENYSK KGKGKTKLRK QPVSEAENKD KPNRGEKQLL IPFTGKGYVL GETSNFSSGK CITSHAINES QEPLSQDHSA NALRPHSKTE VKFEQNGPSK KTSVASPVLS TSHQNVLSNY FSKVSVASSK AFRSVSGSPV KSLTVGDSTT KSVSAGSQRR VTSSRTSLRN SLKAMESTYV TVPQDAGGPE GKLPSKRPRI EDKTFFDLFF IKKEQAQSGG GDVTSSSHPP AAAQSPSGAS GQSRVVHCPV CQDEVSETQI NEHLDWCLER DSTQVKS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity. DPCs are highly toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription, and which are induced by reactive agents, such as UV light or formaldehyde. Associates with the DNA replication machinery and specifically removes DPCs during DNA synthesis. Acts as a pleiotropic protease for DNA-binding proteins cross-linked with DNA, such as TOP1, TOP2A, histones H3 and H4. Mediates degradation of DPCs that are not ubiquitinated, while it is not able to degrade ubiquitinated DPCs. SPRTN activation requires polymerase collision with DPCs followed by helicase bypass of DPCs. Involved in recruitment of VCP/p97 to sites of DNA damage. Also acts as an activator of CHEK1 during normal DNA replication by mediating proteolytic cleavage of CHEK1, thereby promoting CHEK1 removal from chromatin and subsequent activation. Does not activate CHEK1 in response to DNA damage. May also act as a 'reader' of ubiquitinated PCNA: recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis.
  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Spartan family
  • 數據庫鏈接：


主站蜘蛛池模板： 粉嫩大学生无套内射无码卡视频| 97久久久人妻一区精品| 国产av国内精品jk制服| 中文人妻av久久人妻18| 中文字幕aav| 亚洲日韩成人无码不卡网站| 亚洲丁香五月天缴情综合| 豆国产96在线 | 亚洲| 亚洲综合狠狠丁香五月| 精品无码乱码av| 国产精品成人av在线观看| av午夜久久蜜桃传媒软件| 美女被张开双腿日出白浆| 末成年毛片在线播放| 国产精品门事件av| 特级毛片在线大全免费播放| 中文字幕无码av波多野吉衣| 亚洲国产精品无码专区| 国产制服丝袜亚洲高清| 人人爽人人爽人人片a免费| 疯狂三人交性欧美| 边添小泬边狠狠躁视频| 日韩少妇白浆无码系列| 婷婷丁香六月激情综合啪| 国产亚洲产品影市在线产品| 老司机亚洲精品影院无码| 永久免费男同av无码入口| 精品无码成人网站久久久久久| 国产呻吟久久久久久久92| 精品黑人一区二区三区| 国产成人精品免费视频大全五级| 亚洲国产aⅴ综合网| 狂野欧美激情性xxxx| 国产手机在线国内精品| 性中国妓女毛茸茸视频| 日本乱码伦午夜福利在线| 性久久久久久久| 久久精品夜色噜噜亚洲a∨| 国产精品亚洲精品一区二区| 久久天天躁狠狠躁夜夜2019| 玩弄中年熟妇正在播放|