在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Spastin (SPAST), partial

Recombinant Bovine Spastin (SPAST), partial

  • 中文名稱：
    牛SPAST重組蛋白
  • 貨號(hào)：
    CSB-YP022488BO1
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SPAST重組蛋白
  • 貨號(hào)：
    CSB-EP022488BO1
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SPAST重組蛋白
  • 貨號(hào)：
    CSB-EP022488BO1-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SPAST重組蛋白
  • 貨號(hào)：
    CSB-BP022488BO1
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SPAST重組蛋白
  • 貨號(hào)：
    CSB-MP022488BO1
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SPAST
  • Uniprot No.：
  • 別名：
    SPAST; SPG4; Spastin
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches.
  • 基因功能參考文獻(xiàn)：
    1. Results demonstrate a causal relationship between the SPAST mutation and bovine spinal dysmyelination. PMID: 19714378
    2. A defective SPAST gene in cattle is associated with a recessive, congenital neurodegenerative disease, which is characterized by pathological changes of the myelin sheaths in the spinal cord. PMID: 19714378
  • 相關(guān)疾病：
    Defects in SPAST are the cause of bovine spinal dysmyelination (BSD), a neurodegenerative disorder characterized by pathological changes of the myelin sheaths in the spinal cord. Defects appear immediately at birth and include lateral recumbency with slight to moderate opisthotonos, body tremor, and spastic extension of the limbs. General muscle atrophy due to denervation occurs to variable degrees and is most obvious in the hind limbs. BSD is a longstanding problem in the American Brown Swiss (ABS) breed and in several European cattle breeds upgraded with ABS. The morphological cause of the phenotype is bilateral symmetrical hypo- and demyelination of axons in the cervical and thoracic segments of the spinal cord. The disease is caused by mutations affecting the gene represented in this entry.
  • 亞細(xì)胞定位：
    Membrane; Peripheral membrane protein. Endoplasmic reticulum. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm.
  • 蛋白家族：
    AAA ATPase family, Spastin subfamily
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 久久国产人妻一区二区| 超级av在线天堂东京热| 亚洲中文字幕在线第二页| 久久人人超碰精品caoporen| 国产精品无需播放器在线观看| 99久久人人爽亚洲精品美女| а天堂8中文最新版在线官网| 天堂aⅴ无码一区二区三区| 亚洲国产成人精品无码区二本| 久青青视频在线观看久| 亚洲一区二区三区写真| 最新高清中文字幕免费mv| 无码精品a∨在线观看十八禁| 日本中文一区二区三区亚洲| 三个男吃我奶头一边一个视频| yy111111少妇无码理论片| 久久亚洲精品无码爱剪辑| 在线播放偷拍一区精品| 成人艳情一二三区| 亚洲国色天香卡2卡3卡4| 吃奶摸下高潮60分钟免费视频| 日韩精品无码不卡无码| 国产偷国产偷亚洲高清日韩| 99久久婷婷国产综合精品 | 99re久久资源最新地址| 久久只精品99品免费久23| 欧美性猛交ⅹxxx乱大交妖精| 国产又爽又黄无码无遮挡在线观看| 成人无码在线视频网站| 精品人妻无码一区二区三区蜜桃一| 亚洲精品第一国产综合野草社区| 国产69精品久久久久久妇女迅雷| 中国少妇偷人hd| 国产精品久久久久久久久电影网| 成人无码www在线看免费| 性欧美videofree高清精品| 无码人妻一区二区三区免费手机 | 欧美xxxx做受欧美1314| 人妻丰满av无码中文字幕| 熟女人妻aⅴ一区二区三区60路| 国产gv在线观看受被做哭|