在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Lysosomal-associated transmembrane protein 4B (LAPTM4B), partial

  • 中文名稱:
    牛LAPTM4B重組蛋白
  • 貨號:
    CSB-YP765155BO1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛LAPTM4B重組蛋白
  • 貨號:
    CSB-EP765155BO1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛LAPTM4B重組蛋白
  • 貨號:
    CSB-EP765155BO1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛LAPTM4B重組蛋白
  • 貨號:
    CSB-BP765155BO1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛LAPTM4B重組蛋白
  • 貨號:
    CSB-MP765155BO1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LAPTM4B
  • Uniprot No.:
  • 別名:
    LAPTM4B; Lysosomal-associated transmembrane protein 4B
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for optimal lysosomal function. Blocks EGF-stimulated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation. Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stimulating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation. Plays a role as negative regulator of TGFB1 production in regulatory T cells. Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways.
  • 基因功能參考文獻:
    1. This study reports for the first time that bovine LAPTM4B in granulosa cells is present in both unubiquinated and ubiquinated forms, and is differentially expressed in developing ovarian follicles PMID: 25881887
    2. LAPTM4B is differentially expressed at the mRNA and protein levels in different bovine tissues. The mRNA yields a 26.3 kDa protein that undergoes mono-ubiquitination resulting in a 31.5 kDa isoform. Immunohistochemical observations revealed that LAPTM4B expression was highly variable among tissues, and among similar and adjacent cell types. LAPTM4B may confer protection against the accumulation of metabolic byproducts. PMID: 25881887
  • 亞細胞定位:
    Endomembrane system; Multi-pass membrane protein. Late endosome membrane. Cell membrane. Cell projection. Lysosome membrane. Endosome membrane. Endosome, multivesicular body membrane. Endosome, multivesicular body lumen.
  • 蛋白家族:
    LAPTM4/LAPTM5 transporter family
  • 組織特異性:
    Strongly expressed in fetal ovary, testis, adrenal gland, liver and uterus, and weakly expressed in the spleen.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲www啪成人一区二区麻豆| 精品国产在天天在线观看| 老色69久久九九精品高潮| 亚洲精品久久久久国产| 亚洲午夜爱爱香蕉片| 国产日韩精品欧美一区喷水 | 99re在线播放| 两个奶头被吃高潮视频| 熟女精品视频一区二区三区| 亚洲国产欧美国产综合久久 | 国产亚洲精品精品精品| 亚洲性无码av中文字幕| 国产亚洲精品第一综合另类灬| 一本清日本在线视频精品| 亚洲国产精品一区二区成人片| 日韩无码电影| 九九热线精品视频16| 日本久久夜夜一本婷婷| 国产一区二区三区精品视频 | 一本天堂v无码亚洲道久久| 亚瑟av亚洲精品一区二区| 久久99精品久久久大学生| 西西人体大胆午夜啪啪| 亚洲最大av一区二区三区| 亚洲国产精品无码中文lv| 丁香啪啪综合成人亚洲| 精品无人乱码一区二区三区的特点| 麻豆ā片免费观看在线看 | 久久精品国产亚洲a片高清不卡| 六月丁香亚洲综合在线视频| 亚洲国产色播av在线| 无遮挡又黄又刺激的视频| 国产va免费精品高清在线| 亚洲精品久久yy5099| 天天天天做夜夜夜做| 亚洲精品乱码久久久久久金桔影视 | 中文字幕日韩欧美一区二区三区 | 日韩亚洲国产激情一区浪潮av| 无码aⅴ在线观看| 老司机无码精品a| 亚洲综合网站精品一区二区|