在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Aotus nancymaae Serine/threonine-protein kinase 4 (STK4)

  • 中文名稱:
    Recombinant Aotus nancymaae Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-YP022855AUV
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Aotus nancymaae Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-EP022855AUV
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Aotus nancymaae Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-EP022855AUV-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Aotus nancymaae Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-BP022855AUV
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Aotus nancymaae Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-MP022855AUV
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    STK4; Serine/threonine-protein kinase 4; EC 2.7.11.1) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit; MST1/N); Serine/threonine-protein kinase 4 18kDa subunit; MST1/C)]
  • 種屬:
    Aotus nancymaae (Ma's night monkey)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-487
  • 氨基酸序列
    METVQLRNPP RRQLKKLDED SLTKQPEEVF DVLEKLGEGS YGSVYKAIHK ETGQIVAIKQ VPVESDLQEI IKEISIMQQC DSHHVVKYYG SYFKNTDLWI VMEYCGAGSV SDIIRLRNKT LTEDEIATIL QSTLKGLEYL HFMRKIHRDI KAGNILLNTE GHAKLADFGV AGQLTDTMAK RNTVIGTPFW MAPEVIQEIG YNCVADIWSL GITAIEMAEG KPPYADIHPM RAIFMIPTNP PPTFRKPELW SDNFTDFVKQ CLVKSPEQRA TATQLLQHPF VKSAKGVSIL RDLINEAMDV KLKRQESQQR EVDQDDEENS EEDEMDSGTM VRAVGDEMGT VRVASTMTDG ANTMIEHDDT LPSQLGTMVI NAEDEEEEGT MKRRDETMQP AKPSFLEYFE QKEKENQINS FGKSIPGPLQ NSSDWKVPQD GDYEFLKSWT VEDLQKRLLA LDPMMEQEIE EIRQKYQSKR QPILDAIEAK KRRQQNF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation. Phosphorylates 'Ser-14' of histone H2B (H2BS14ph) during apoptosis. Phosphorylates FOXO3 upon oxidative stress, which results in its nuclear translocation and cell death initiation. Phosphorylates MOBKL1A, MOBKL1B and RASSF2. Phosphorylates TNNI3 (cardiac Tn-I) and alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). Phosphorylates FOXO1 on 'Ser-212' and regulates its activation and stimulates transcription of PMAIP1 in a FOXO1-dependent manner. Phosphorylates SIRT1 and inhibits SIRT1-mediated p53/TP53 deacetylation, thereby promoting p53/TP53 dependent transcription and apoptosis upon DNA damage. Acts as an inhibitor of PKB/AKT1. Phosphorylates AR on 'Ser-650' and suppresses its activity by intersecting with PKB/AKT1 signaling and antagonizing formation of AR-chromatin complexes.
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily


主站蜘蛛池模板: 国产亚洲精品久久久久5区| 亚洲欧美国产精品久久| 亚洲a成人片在线观看| 国产精品爱啪在线播放| 同性女女黄h片在线播放| 亚洲一卡2卡3卡4卡精品| 国产乱人无码伦av在线a| 亚洲国产综合无码一区| 色综久久综合桃花网国产精品| 欧美日韩中文在线字幕视频| 久久精品无码精品免费专区| 影音先锋男人站| 久久精品成人免费国产片小草| 伊人久久大香线蕉成人| 久久人人爽人人人人片| 国产精品久久久久蜜臀| 精品国产免费观看久久久| 欧美日韩国产综合新一区| 亚洲欧洲日产国码无码av一| 自偷自拍亚洲综合精品| 日韩做a爰片久久毛片a片| 国产精品日本一区二区不卡视频| 男女性杂交内射女bbwxz| 伊人色综合久久天天人守人婷| 久久综合av色老头免费观看| 水蜜桃亚洲一二三四在线| 隔壁老王国产在线精品| 啪啪后入内射日韩| 免费的av网站手机版| 国产精品免费久久久久影院| 777奇米四色成人影视色区| 欧美人与动性xxxxbbbb| аⅴ资源天堂资源库在线| 色欲精品国产一区二区三区av | 欧美黑人巨大videos在线| 中文字幕人妻丝袜成熟乱 | 激情综合五月| 国产午夜亚洲精品久久| 国产牛仔裤网站精品| 亚洲va国产va天堂va久久| 国产精品无码av片在线观看播|