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  4. Recombinant Adenomatous polyposis coli protein-related protein 1 (41365), partial

Recombinant Adenomatous polyposis coli protein-related protein 1 (41365), partial

  • 中文名稱：
    Recombinant Adenomatous polyposis coli protein-related protein 1(41365) ,partial
  • 貨號：
    CSB-YP638587CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Adenomatous polyposis coli protein-related protein 1(41365) ,partial
  • 貨號：
    CSB-EP638587CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Adenomatous polyposis coli protein-related protein 1(41365) ,partial
  • 貨號：
    CSB-EP638587CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Adenomatous polyposis coli protein-related protein 1(41365) ,partial
  • 貨號：
    CSB-BP638587CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Adenomatous polyposis coli protein-related protein 1(41365) ,partial
  • 貨號：
    CSB-MP638587CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    apr-1
  • Uniprot No.：
  • 別名：
    apr-1; K04G2.8Adenomatous polyposis coli protein-related protein 1; APC-related protein 1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing the polarity of the mother cell which forms the asymmetries of the daughter nuclei. During the L4 larval stage, it is required for the asymmetric division and self-renewal of seam cells. Thought to regulate export of wrm-1 from the nucleus possibly as part of a complex involving pry-1.
  • 基因功能參考文獻：
    1. Caenorhabditis elegans APR-1/APC is an attenuator of the pulling forces acting on the mitotic spindle PMID: 29348204
    2. These results suggest that beta-catenin and APC may regulate asymmetric divisions or Wnt signaling.[APC] PMID: 17276345
    3. The polarity of APR-1 cortical localization is controlled by PRY-1 (C. elegans Axin), such that PRY-1 controls the polarity of both SYS-1 and WRM-1 asymmetries. PMID: 24762815
    4. Apoptotic cell clearance and migration of the distal tip cell require the APC/APR-1. PMID: 20126385
  • 亞細胞定位：
    Cell junction, adherens junction. Cytoplasm. Nucleus.
  • 蛋白家族：
    Adenomatous polyposis coli (APC) family
  • 組織特異性：
    During the L1 stage, expressed in vulval precursor cells (P3-8.p), seam cells and excretory cells.
  • 數據庫鏈接：

    KEGG: cel:CELE_K04G2.8

    STRING: 6239.K04G2.8b

    UniGene: Cel.16875



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