在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. ENPP3 Recombinant Monoclonal Antibody

ENPP3 Recombinant Monoclonal Antibody

  • 中文名稱：
    ENPP3重組抗體
  • 貨號：
    CSB-RA007681MA1HU
  • 規格：
    ￥1320
  • 圖片：
    • The Binding Activity of Macaca fascicularis ENPP3 with Anti-ENPP3 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 (CSB-MP4278MOV) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 3.313-4.724 ng/mL.
    • The Binding Activity of Huamn ENPP3 with Anti- ENPP3 Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3(CSB-MP007681HU) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 2.151-2.492 ng/mL
    • Untransfected HEK293T cells surface (green line) and transfected Human ENPP3 HEK293T stable cells surface (red line) were stained with anti-ENPP3 recombinant antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產品詳情

  • 產品描述：
    ENPP3重組單克隆抗體（產品編號：CSB-RA007681MA1HU）是針對外核苷酸焦磷酸酶/磷酸二酯酶3（ENPP3）研發的高特異性科研用抗體。ENPP3作為跨膜糖蛋白，屬于水解酶家族成員，參與調控細胞外核苷酸代謝和嘌呤能信號通路，在特定細胞類型的表面標記及微環境調控中發揮重要作用。本產品通過重組表達技術制備，經ELISA和流式細胞術（FC）雙重驗證，展現出優異的抗原結合能力，可精準識別天然構象下的ENPP3蛋白，適用于細胞表面抗原檢測及蛋白表達水平分析。在ELISA實驗中表現出高靈敏度，能夠有效檢測低豐度靶蛋白；流式分析驗證了其在活細胞或固定化樣本中特異性識別ENPP3的能力，適用于細胞亞群分選及功能研究。該抗體具有嚴格的種屬反應性（人源）和批次間一致性，可滿足腫瘤生物學、免疫微環境研究及代謝相關信號通路探索等科研需求，為解析ENPP3在疾病模型中的作用機制提供可靠工具。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Alkaline phosphodiesterase I antibody; ARHR2 antibody; B10 antibody; CD203c antibody; CD203c antigen antibody; dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3) antibody; dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3) antibody; E NPP 3 antibody; E-NPP 3 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 3 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 antibody; ENPP3 antibody; ENPP3_HUMAN antibody; gp130RB13 6 antibody; gp130RB136 antibody; M6S1 antibody; NPP1 antibody; NPP3 antibody; NPPase antibody; NPPS antibody; Nucleotide pyrophosphatase antibody; PC 1 antibody; PC-1 antibody; PCA1 antibody; PD Ibeta antibody; PD-Ibeta antibody; PDNP1 antibody; PDNP3 antibody; Phosphodiesterase I beta antibody; Phosphodiesterase I/nucleotide pyrophosphatase 3 antibody; phosphodiesterase i/nucleotide pyrophosphatase beta antibody
  • 反應種屬：
    Human, Macaca fascicularis
  • 免疫原：
    Recombinant Human ENPP3 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    3B2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,FC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP. Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells. Has also alkaline phosphodiesterase activity.
  • 基因功能參考文獻：
    1. We showed the ability of the immunological marker CD203c to predict the clinical efficacy of sublingual immunotherapy on rhinitis subjects allergic to Parietaria. PMID: 29702283
    2. Basophil CD203c surface expression reliably discriminated cystic fibrosis with allergic bronchopulmonary aspergillosis from cystic fibrosis with Aspergillus colonization and cystic fibrosis over time. PMID: 26585435
    3. Expression of CD203c on basophils as a marker of immunoglobulin E-mediated (L)-asparaginase allergy. PMID: 23581640
    4. Anaphylactic transfusion reaction in homozygous haptoglobin deficiency detected by CD203c expression on basophils. PMID: 24497482
    5. ENPP3 is a regulator of N-acetylglucosaminyltransferase GnT-IX (GnT-Vb) PMID: 23960081
    6. The early signaling requirements for the CD11b/CD203c compartment expression and CD63 degranulation provide support for the hypothesis that CD11b and CD203c reside in a similar compartment. PMID: 22722613
    7. Subjects with nut allergy show an increase of basophil CD203c levels at baseline and following rapid ex vivo stimulation with nut allergen PMID: 20975283
    8. Asthma exacerbation was accompanied by increased expression of CD203c on basophils that decreased significantly during remission PMID: 20159259
    9. Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis. PMID: 20047266
    10. Data show that low and high dilutions of histamine inhibit CD203c up-regulation in anti-IgE stimulated basophils. PMID: 19418203
    11. E-NPP3 is associated with carcinogenesis of human colon cancer and that serum E-NPP3 might be a tumor marker of colon carcinoma PMID: 14533006
    12. E-NPP3 is involved in the infiltration of neoplastic bile duct carcinoma PMID: 15072822
    13. Our data demonstrate that leptin promotes platelet activation, provides a mechanistic basis for the prothrombotic effect of this hormone, and identifies a potentially novel therapeutic avenue to limit obesity-associated cardiovascular disease. PMID: 15886225
    14. In conclusion, using well-defined experimental conditions, the measurement of CD203c up-regulation on basophils in response to specific allergens is as reliable as CD63-BAT for the in vitro diagnosis of patients with IgE-mediated allergy. PMID: 17275019

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Secreted.
  • 蛋白家族：
    Nucleotide pyrophosphatase/phosphodiesterase family
  • 組織特異性：
    Detected on bile ducts in liver, and in blood serum (at protein level). Detected in prostate and uterus. Detected on basophils, but not neutrophils.
  • 數據庫鏈接：

    HGNC: 3358

    OMIM: 602182

    KEGG: hsa:5169

    STRING: 9606.ENSP00000350265

    UniGene: Hs.486489



主站蜘蛛池模板： 国内少妇高潮嗷嗷叫在线播放| 国产成人无码av在线影院| 免费人成在线观看视频无码| 免费无码黄十八禁网站在线观看| 伊人久久大香线蕉综合75| 欧美色综合天天久久综合精品| 欧美亚洲偷图色综合| 日本少妇内射视频播放舔| 午夜嘿嘿嘿影院| 国产自偷自偷免费一区| 六月丁香婷婷色狠狠久久| 女性自慰网站免费观看w| 亚洲精品1卡2卡三卡23卡| 国产精品久久久久久久久久久久午夜片| 久久无码av中文出轨人妻| 国产婷婷精品av在线| 99久re热视频这里只有精品6| 6080yyy午夜理论片中无码| 人妻丰满熟妇av无码区hd| 国产精品_九九99久久精品| 吃奶呻吟张开双腿做受在线播放 | 精品午夜福利在线观看| 吃奶呻吟打开双腿做受在线视频 | 亚洲午夜久久久无码精品网红a片| 人与性动交aaaabbbb| 美女国产毛片a区内射| 亚洲vav在线男人的天堂| 羞羞影院午夜男女爽爽| 丁香五月欧美成人| 亚洲国产精品久久久久婷蜜芽| 天堂在线最新版www中文| 欧美另类人妖| 亚洲欧美日韩精品久久亚洲区| 秋霞鲁丝无码一区二区三区| 99大香伊乱码一区二区| 国产成人a视频高清在线观看| 欧洲熟妇色xxxx欧美老妇老头多毛 | 最新精品视频2019在线视频| 亚洲五月色丁香婷婷婷| 午夜精品一区二区三区免费视频| 色先锋资源久久综合5566|