在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. CEACAM8 Recombinant Monoclonal Antibody

CEACAM8 Recombinant Monoclonal Antibody

  • 中文名稱：
    CEACAM8重組抗體
  • 貨號：
    CSB-RA005168MA1HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Human CEACAM8 with Anti-CEACAM8 Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM8 (CSB-MP005168HU) at 2 μg/mL can bind Anti-CEACAM8 recombinant antibody, the EC50 is 19.38-21.68 ng/mL.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA005168MA1HU 是靶向人源 CEACAM8 蛋白的重組單克隆抗體，采用小鼠雜交瘤技術(shù)制備，具有高親和力與批次穩(wěn)定性。CEACAM8 屬于癌胚抗原相關(guān)細胞黏附分子家族（CEACAM），主要在中性粒細胞表面表達，參與炎癥反應(yīng)調(diào)控及病原體識別，其異常表達與慢性炎癥性疾病、感染性疾病及免疫調(diào)節(jié)研究相關(guān)。本抗體經(jīng) ELISA 驗證可特異性識別天然及重組 CEACAM8 蛋白，適用于體外樣本中靶蛋白的定性或半定量檢測。應(yīng)用場景涵蓋炎癥機制研究、免疫細胞功能分析以及相關(guān)信號通路探索，可為體外細胞模型、蛋白互作研究或免疫組化實驗提供可靠工具，助力科研人員解析 CEACAM8 在免疫應(yīng)答中的分子作用。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Carcinoembryonic antigen CGM6 antibody; Carcinoembryonic antigen gene family member 6 antibody; Carcinoembryonic antigen related cell adhesion molecule 8 antibody; Carcinoembryonic antigen-related cell adhesion molecule 8 antibody; CD 66b antibody; CD 67 antibody; CD66b antibody; CD66b antigen antibody; CD67 antibody; CD67 antigen antibody; CEACAM 8 antibody; CEACAM8 antibody; CEAM8_HUMAN antibody; CGM 6 antibody; CGM6 antibody; NCA 95 antibody; NCA95 antibody; Non-specific cross-reacting antigen NCA-95 antibody; Nonspecific cross reacting antigen NCA 95 antibody; Nonspecific cross reacting antigen NCA95 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human CEACAM8 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    22H9
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
  • 基因功能參考文獻：
    1. Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. PMID: 27863478
    2. Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another. PMID: 26483485
    3. Granulocytes from type 2 diabetes patients display higher granulocyte cell surface expression of CD66b compared with values of healthy controls. PMID: 23686079
    4. The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation. PMID: 21470677
    5. All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes. PMID: 17909799
    6. CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b. PMID: 18056392

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 組織特異性：
    Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1820

    OMIM: 615747

    KEGG: hsa:1088

    STRING: 9606.ENSP00000244336

    UniGene: Hs.41



主站蜘蛛池模板： 蜜臀avwww国产天堂| 久久综合色鬼综合色| 亚洲中文无码人a∨在线导航| 亚洲精品无码久久千人斩| 日韩精品一区二区大桥未久| 人妻三级日本香港三级极97| 精品国产亚洲一区二区三区 | 成人做受视频试看120秒| 男女做爰猛烈啪啪吃奶动| 中文字幕久热精品视频在线| 日本亚洲欧洲无免费码在线| 波多野结衣的av一区二区三区| 国产免费麻传媒精品国产av| 被窝影院午夜无码国产| 天天躁夜夜躁狠狠躁2021a2| 亚洲国产精品热久久| 国产欧美熟妇另类久久久| 天天拍夜夜添久久精品| 亚洲日本精品国产一区vr| 樱花草视频www日本韩国| 麻豆精品一区二区综合av| 国产日产欧产精品精品蜜芽 | 伊人大杳焦在线| 国产女人18毛片水真多18精品| 中文天堂在线www| 国产成人无码18禁午夜福利网址| 国自产拍偷拍精品啪啪av| 伊人成色综合网| 亚洲一区二区三区av无码| 国产女人喷潮视频免费| 欧美亚洲日本国产其他| 小罗莉极品一线天在线| 久久综合色之久久综合| 草草久久97超级碰碰碰| 国产精品人妻熟女男人的天堂| 玩弄白嫩少妇xxxxx性| 放荡的美妇在线播放| 最新亚洲伦理中文字幕| 精品一二三区久久aaa片| 国内精品国产成人国产三级| 国产成人8x人在线视频软件|