在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) ELISA kit

Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) ELISA kit

  • 中文名稱：
    人癌胚抗原相關細胞粘附分子8(CEACAM8)酶聯免疫試劑盒
  • 貨號：
    CSB-EL005168HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人癌胚抗原相關細胞粘附分子8(CEACAM8)酶聯免疫試劑盒（CSB-EL005168HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的CEACAM8含量。CEACAM8，也稱為CD66b，是免疫球蛋白超家族的一員，主要在粒細胞中表達。它通過調節細胞間粘附和信號傳導參與免疫反應，尤其在腫瘤微環境中發揮重要作用。CEACAM8的研究機制涉及其在腫瘤中的調節機制、免疫信號機制以及與多種疾病如乳腺癌、宮頸癌和膀胱癌的關系。試劑盒檢測范圍為0.625 ng/mL-40 ng/mL，適用于體外檢測多種生物樣本中CEACAM8的表達水平，可為研究中性粒細胞介導的免疫反應機制、炎癥相關疾病模型建立及腫瘤微環境調控等基礎科研領域提供可靠工具，其定量數據亦可作為探索CEACAM8作為炎癥或腫瘤相關生物標志物的研究依據。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Carcinoembryonic antigen CGM6 ELISA Kit; Carcinoembryonic antigen gene family member 6 ELISA Kit; Carcinoembryonic antigen related cell adhesion molecule 8 ELISA Kit; Carcinoembryonic antigen-related cell adhesion molecule 8 ELISA Kit; CD 66b ELISA Kit; CD 67 ELISA Kit; CD66b ELISA Kit; CD66b antigen ELISA Kit; CD67 ELISA Kit; CD67 antigen ELISA Kit; CEACAM 8 ELISA Kit; CEACAM8 ELISA Kit; CEAM8_HUMAN ELISA Kit; CGM 6 ELISA Kit; CGM6 ELISA Kit; NCA 95 ELISA Kit; NCA95 ELISA Kit; Non-specific cross-reacting antigen NCA-95 ELISA Kit; Nonspecific cross reacting antigen NCA 95 ELISA Kit; Nonspecific cross reacting antigen NCA95 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    0.625 ng/mL-40 ng/mL
  • 靈敏度：
    0.156 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Others
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CEACAM8 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %91
    Range %85-96
    1:2Average %96
    Range %92-103
    1:4Average %102
    Range %95-108
    1:8Average %88
    Range %86-91
  • 回收率：
    The recovery of human CEACAM8 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9186-95
    EDTA plasma (n=4)9794-101
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    402.322 2.525 2.424 2.273
    201.989 1.966 1.978 1.827
    101.365 1.481 1.423 1.272
    50.975 1.052 1.014 0.863
    2.50.603 0.625 0.614 0.463
    1.250.369 0.347 0.358 0.207
    0.6250.272 0.280 0.276 0.125
    00.146 0.155 0.151
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
  • 基因功能參考文獻：
    1. Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. PMID: 27863478
    2. Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another. PMID: 26483485
    3. Granulocytes from type 2 diabetes patients display higher granulocyte cell surface expression of CD66b compared with values of healthy controls. PMID: 23686079
    4. The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation. PMID: 21470677
    5. All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes. PMID: 17909799
    6. CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b. PMID: 18056392

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 組織特異性：
    Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
  • 數據庫鏈接：

    HGNC: 1820

    OMIM: 615747

    KEGG: hsa:1088

    STRING: 9606.ENSP00000244336

    UniGene: Hs.41



主站蜘蛛池模板： 亚洲中文欧美在线视频| 国精产品999国精产| 中文天堂在线www最新版官网| 日本熟妇人妻videos| 久久国产精品萌白酱免费| 99爱在线精品视频免费观看| 人妻精品久久久久中文字幕69| 夜夜夜夜曰天天天天拍国产| 永久免费观看美女裸体的网站 | 丰腴饱满的极品熟妇| 2018年亚洲欧美在线v| 中文无码精品a∨在线观看| 99久热国产精品视频尤物| 色妞ww精品视频7777| 精品人妻伦一二三区久久| 久久久欧美精品激情| 99久热国产精品视频尤物| 人妻夜夜添夜夜无码av| 蜜臀av色欲a片无码精品一区| 国产精品sm捆绑调教视频| 亚洲欧美日韩综合av| 天天摸日日摸狠狠添| 色婷婷综合久久久久中文一区二区| 久久久噜噜噜久久熟女色| 人妻少妇久久中文字幕| 天天综合天天做天天综合| 色欲av巨乳无码一区二区| 久久亚洲色www成人不卡| 性xxxx18免费观看视频| 青草视频在线播放| 色v99在线影院| 国产午夜理论不卡在线观看| 人妻无码人妻有码中文字幕| 免费国产又色又爽又黄的网站| 成人国产精品无码网站| 久久精品国产清高在天天线| 成人做受黄大片| 成人国产网站v片免费观看| 天下第一社区视频www日本| 日韩丰满少妇无码内射| 欧美又粗又长又爽做受|