在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. CEACAM8 Recombinant Monoclonal Antibody

CEACAM8 Recombinant Monoclonal Antibody

  • 中文名稱：
    CEACAM8重組抗體
  • 貨號：
    CSB-RA937940A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Overlay Peak curve showing A549 cells surface stained with CSB-RA937940A0HU (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他：

產品詳情

  • 產品描述：
    CEACAM8重組單克隆抗體（CUSABIO貨號：CSB-RA937940A0HU）是針對粒細胞特異性標志物CEACAM8開發的高特異性檢測工具。CEACAM8作為癌胚抗原相關細胞黏附分子家族成員，在中性粒細胞活化、炎癥反應及病原體防御中發揮重要作用。本產品經過嚴格的ELISA和流式細胞術（FC）驗證，能特異性識別天然構象的CEACAM8蛋白，FC推薦使用稀釋比為1:50-1:200，適用于體外檢測人源樣本中CEACAM8的表達水平。在科研領域，該抗體可應用于粒細胞亞群分型、炎癥相關免疫細胞功能研究，以及感染性疾病或自身免疫性疾病模型中粒細胞活化機制的探索。其重組單克隆特性保障了批次間的高度一致性，為細胞表面標記分析、免疫應答機制研究提供可靠工具，助力研究者深入解析CEACAM8在先天免疫調控中的生物學功能。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Carcinoembryonic antigen-related cell adhesion molecule 8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b), CEACAM8, CGM6
  • 反應種屬：
    Human
  • 免疫原：
    A synthesized peptide derived from Human CEACAM8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    24H12
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
  • 基因功能參考文獻：
    1. Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. PMID: 27863478
    2. Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another. PMID: 26483485
    3. Granulocytes from type 2 diabetes patients display higher granulocyte cell surface expression of CD66b compared with values of healthy controls. PMID: 23686079
    4. The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation. PMID: 21470677
    5. All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes. PMID: 17909799
    6. CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b. PMID: 18056392

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 組織特異性：
    Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
  • 數據庫鏈接：

    HGNC: 1820

    OMIM: 615747

    KEGG: hsa:1088

    STRING: 9606.ENSP00000244336

    UniGene: Hs.41



主站蜘蛛池模板： 乱妇乱女熟妇熟女网站| 国产亚洲精品久久久久久久软件 | 久久亚洲国产成人影院| 欧美va亚洲va在线观看日本| 无码人妻丰满熟妇啪啪7774| 欧美 亚洲 国产 制服 中文 | 亚洲欧美日本久久综合网站| 99在线 | 亚洲| 国语少妇高潮对白在线| 少妇愉情理伦片bd| 精品深夜av无码一区二区老年| 欧美老妇与zozozo交| 在线亚洲精品国产一区麻豆| 人人揉揉揉香蕉大免费| 日韩亚洲国产主播在线不卡| 国产裸拍裸体视频在线观看| 色翁荡熄又大又硬又粗又视频图片 | 丰满少妇69激情啪啪无| 久久www免费人成精品| 日韩在线永久免费播放| 久久九九精品国产av片国产| а天堂中文最新版在线| 亚洲国产精品自产在线播放| r级无码视频在线观看| 99精品国产福利在线观看| 丁香五月激情综合亚洲| 久久久精品94久久精品| 日本真人做爰免费视频120秒| 成人免费看吃奶视频网站| 亚州中文字幕无码中文字幕| 琪琪午夜理论片福利在线观看| 国产精品无码一本二本三本色 | 精品无人区码一码二码三码区别| 在线无码av一区二区三区| 妺妺窝人体色www聚色窝| 中文字幕日韩精品一区二区三区| 超碰aⅴ人人做人人爽| 97久久超碰精品视觉盛宴| 日本免费一区二区三区| 亚洲精品久久久中文字幕痴女| 蜜臀亚洲精品国产aⅴ综合第一 |