在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. mutT Antibody

mutT Antibody

Rare Species
  • 中文名稱：
    mutT兔多克隆抗體
  • 貨號：
    CSB-PA357355HA01ENV
  • 規格：
    ￥440
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli mutT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    mutT
  • 別名：
    mutT antibody; b0099 antibody; JW0097 antibody; 8-oxo-dGTP diphosphatase antibody; 8-oxo-dGTPase antibody; EC 3.6.1.55 antibody; 7,8-dihydro-8-oxoguanine-triphosphatase antibody; Mutator protein MutT antibody; dGTP pyrophosphohydrolase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli 8-oxo-dGTP diphosphatase protein (1-129AA)
  • 免疫原種屬：
    Escherichia coli
  • 標記方式：
    Non-conjugated

    本頁面中的產品，mutT Antibody (CSB-PA357355HA01ENV)，的標記方式是Non-conjugated。對于mutT Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA357355HB01ENV mutT Antibody, HRP conjugated ELISA
    FITC CSB-PA357355HC01ENV mutT Antibody, FITC conjugated
    Biotin CSB-PA357355HD01ENV mutT Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorporation of 8-oxoGua into DNA and RNA. It prevents replicational errors by removing an oxidatively damaged form of guanine (8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP can be inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT may also ensure transcriptional fidelity, removing 8-oxo-GTP from the ribonucleotide triphosphate pool. However, due to the lower efficiency of RNA polymerase 8-oxo-GTP incorporation, MutT is probably not a major contributor to transcriptional fidelity. It also hydrolyzes 8-oxo-dGDP and 8-oxo-GDP to their monophosphate form. In vitro, can also use dGTP, dGDP and other various nucleoside di- and triphosphates, with much lower efficiency. Works cooperatively with MutM and MutY to prevent accumulation in the DNA of oxidized guanine residues.
  • 基因功能參考文獻：
    1. The study investigated the role of MutT on transcription fidelity and find no increase in epigenetic switch frequency in the absence of MutT function. PMID: 25294823
    2. MutT mutation increased the point-mutation rate 150-fold. PMID: 23248287
    3. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure. PMID: 21147134
    4. MutT hydrolyzes four types of 8-oxoGua (8-oxo-7,8-dihydroguanine)-containing nucleoside diphosphates and triphosphates to the related monophosphates, thereby preventing misincorporation of 8-oxoGua into DNA and RNA. PMID: 15850400
    5. transient state kinetic analysis of the reaction pathway of mutT; findings confirm an iso kinetic mechanism and explain the preferred hydrolysis of 8-oxo-dGTP PMID: 16285737
    6. These results indicate that mutT plays important roles in mutagenesis induced by 2-OH-dATP and 8-OH-dGTP in vivo. PMID: 17150583
    7. The mutT defect does not elevate chromosomal fragmentation in Escherichia coli because of the surprisingly low levels of MutM/MutY-recognized DNA modifications. PMID: 17616589

    顯示更多

    收起更多

  • 蛋白家族：
    Nudix hydrolase family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产激情久久久久久熟女老人av| 成人免费播放视频777777| 国产真人做爰视频免费| 国产真实乱对白精彩久久老熟妇女| 香蕉伊蕉伊中文视频在线| 国产高清女同学巨大乳在线观看 | 国产精品你懂的在线播放| 久久久久免费看成人影片| 无码国产精成人午夜视频| 无尺码精品产品网站| 18禁美女黄网站色大片免费看| 国产成人综合久久精品推最新| 欧美亚洲日本日韩在线| 日本一卡2卡3卡4卡无卡免费网站| 国产精品永久免费| 狠狠色综合久久丁香婷婷| 亚洲国产欧美中文丝袜日韩| 免费精品99久久国产综合精品 | 夜夜高潮夜夜爽高清视频| 99国产精品无码| 97精品一区二区视频在线观看| 六月丁香综合在线视频| 国产成人综合亚洲看片| 国产伦孑沙发午休精品| 中文字幕无码日韩专区免费 | 人人莫人人擦人人看| 小荡货好紧好爽奶头大视频| 久久国产精品一国产精品| 中文无码一区二区视频在线播放量| 国产大学生粉嫩无套流白浆| 久久精品一区二区三区av| 日日拍夜夜嗷嗷叫|日日摸| 男女啪啦猛视频免费| 国产精品毛片久久久久久久| 亚洲精品国产熟女久久久| 日日碰日日摸夜夜爽无码| 青青草原亚洲| 久久久精品人妻一区二区三区 | 天干夜天干天天天爽视频 | 欧美肥妇bwbwbwbxx| 欧美国产日产一区二区|