在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. mutT Antibody, FITC conjugated

mutT Antibody, FITC conjugated

Rare Species
  • 中文名稱：
    mutT兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA357355HC01ENV
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli mutT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    mutT
  • 別名：
    mutT antibody; b0099 antibody; JW0097 antibody; 8-oxo-dGTP diphosphatase antibody; 8-oxo-dGTPase antibody; EC 3.6.1.55 antibody; 7,8-dihydro-8-oxoguanine-triphosphatase antibody; Mutator protein MutT antibody; dGTP pyrophosphohydrolase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli 8-oxo-dGTP diphosphatase protein (1-129AA)
  • 免疫原種屬：
    Escherichia coli
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorporation of 8-oxoGua into DNA and RNA. It prevents replicational errors by removing an oxidatively damaged form of guanine (8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP can be inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT may also ensure transcriptional fidelity, removing 8-oxo-GTP from the ribonucleotide triphosphate pool. However, due to the lower efficiency of RNA polymerase 8-oxo-GTP incorporation, MutT is probably not a major contributor to transcriptional fidelity. It also hydrolyzes 8-oxo-dGDP and 8-oxo-GDP to their monophosphate form. In vitro, can also use dGTP, dGDP and other various nucleoside di- and triphosphates, with much lower efficiency. Works cooperatively with MutM and MutY to prevent accumulation in the DNA of oxidized guanine residues.
  • 基因功能參考文獻：
    1. The study investigated the role of MutT on transcription fidelity and find no increase in epigenetic switch frequency in the absence of MutT function. PMID: 25294823
    2. MutT mutation increased the point-mutation rate 150-fold. PMID: 23248287
    3. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure. PMID: 21147134
    4. MutT hydrolyzes four types of 8-oxoGua (8-oxo-7,8-dihydroguanine)-containing nucleoside diphosphates and triphosphates to the related monophosphates, thereby preventing misincorporation of 8-oxoGua into DNA and RNA. PMID: 15850400
    5. transient state kinetic analysis of the reaction pathway of mutT; findings confirm an iso kinetic mechanism and explain the preferred hydrolysis of 8-oxo-dGTP PMID: 16285737
    6. These results indicate that mutT plays important roles in mutagenesis induced by 2-OH-dATP and 8-OH-dGTP in vivo. PMID: 17150583
    7. The mutT defect does not elevate chromosomal fragmentation in Escherichia coli because of the surprisingly low levels of MutM/MutY-recognized DNA modifications. PMID: 17616589

    顯示更多

    收起更多

  • 蛋白家族：
    Nudix hydrolase family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲精品国偷拍自产在线观看蜜桃| 人妻少妇无码精品专区| 国产如狼似虎富婆找强壮黑人| 寂寞人妻瑜伽被教练日| 亚洲国产成人一区二区三区| 日韩av高清在线看片| 麻豆av一区二区天美传媒| 性一交一无一伦一精一品| 精品aⅴ一区二区三区| 热99re久久国超精品首页| 99久久精品费精品国产| 国产精品涩涩涩视频网站| 老鸭窝视频在线观看| 超碰国产精品人人做人人爱| 国产超碰人人模人人爽人人喊| 日本免费一区二区三区四区五区| 免费做a爰片久久毛片a片| 少妇三级全黄| 国产成人精品.视频| 97se狼狼狼狼狼亚洲网| 久久经精品久久精品免费观看| 国产无套精品一区二区三区| 国产成人精品福利网站| 男女下面一进一出好爽视频| 国产成人青青久久大片| 亚洲精品一区二区三区在线| 国产日韩av无码免费一区二区| 亚洲爆乳成av人在线蜜芽| 131美女爱做视频国产福利| 国产美女精品一区二区三区| 精品噜噜噜噜久久久久久久久| 国产传媒麻豆剧精品av| 亚洲欧美成aⅴ人在线观看| 国产成人精品无码片区在线观看| av在线亚洲欧洲日产一区二区| 日本动漫瀑乳h动漫啪啪免费| 国产亚洲视频中文字幕97精品| 久在线精品视频线观看| 亚洲成在人线免费观看| 人妻中出无码一区二区三区| 亚洲国产精品一区二区成人片|