在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ZC3HC1 Antibody

ZC3HC1 Antibody

  • 中文名稱：
    ZC3HC1兔多克隆抗體
  • 貨號：
    CSB-PA026371GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ZC3HC1
  • 別名：
    hNIPA antibody; NIPA_HUMAN antibody; Nuclear interacting partner of ALK antibody; Nuclear interacting partner of anaplastic lymphoma kinase antibody; Nuclear-interacting partner of ALK antibody; Nuclear-interacting partner of anaplastic lymphoma kinase antibody; zc3hc1 antibody; Zinc finger C3HC type containing 1 antibody; Zinc finger C3HC-type protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ZC3HC1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
  • 基因功能參考文獻(xiàn)：
    1. Common nonsynonymous coding variant in ZC3HC1 (rs11556924) is associated with protection from coronary artery disease. PMID: 28115489
    2. This study shows that the Coronary Artery Disease-associated coding polymorphism in ZC3HC1 alters the dynamics of cell-cycle regulation by NIPA. PMID: 27226629
    3. ZC3HC1 rs11556924 polymorphism is associated with hypertension in a Finnish cohort. PMID: 26266351
    4. Results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in rheumatoid arthritis. PMID: 24286297
    5. The NIPA protein is a human F-box-containing protein that defines an SCF-type E3 ligase (SCF(NIPA)) controlling mitotic entry. PMID: 16009132
    6. Data show that cell cycle-dependent phosphorylation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA)is mediated by extracellular signal-regulated kinase 2 (ERK2). PMID: 22955283
    7. phosphorylated NIPA is degraded in late mitosis in an APC/C(Cdh1)-dependent manner PMID: 22205987
    8. NIPA has an antiapoptotic role in NPM-ALK-mediated signaling events PMID: 12748172

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29913

    KEGG: hsa:51530

    STRING: 9606.ENSP00000351052

    UniGene: Hs.194157



主站蜘蛛池模板： 人妻少妇精品专区性色av| 国产超碰人人模人人爽人人添| 亚洲精品色午夜无码专区日韩| 亚洲国产成人久久综合一区| 无码中文av有码中文av| 亚洲熟妇久久国产精品| 天下第一社区视频www日本| 粉色午夜视频| 玩弄少妇人妻| 国产三级不卡在线观看视频| 日本欧美大码aⅴ在线播放| 色一情一乱一乱一区99av白浆| 色欲色香天天天综合网www| 狠狠躁夜夜躁人人爽蜜桃| 国产人无码a在线西瓜影音| 小污女导航福利入口| www插插插无码免费视频网站| 台湾佬中文娱乐22vvvv| 色妺妺免费影院| 欧美欧洲成本大片免费| 中文字幕高清免费日韩视频在线 | 国内精品人妻无码久久久影院| 色天使亚洲综合一区二区| 欧美大片欧美激情性色a∨在线| 亚洲午夜精品久久久久久app | 精品久久久噜噜噜久久久| 爽死你欧美大白屁股在线| 99久久国产综合精品女图图等你| 中文字幕资源网| 10000部拍拍拍免费视频| 国产精品亚洲а∨天堂网| 人人狠狠综合久久亚洲爱咲| 97碰碰碰人妻无码视频| 国产成人综合久久精品推下载| 国产亚洲欧美日韩在线观看一区 | 99大香伊乱码一区二区| 国产老熟女伦老熟妇露脸| 精品国产成人一区二区三区 | 国产精品无码午夜免费影院| 麻豆网神马久久人鬼片| 男男gv白嫩小受gv在线播放|