在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ZC3HC1 Antibody

ZC3HC1 Antibody

  • 中文名稱：
    ZC3HC1兔多克隆抗體
  • 貨號：
    CSB-PA801246ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: ZC3HC1 antibody at 1.08µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 56, 54, 48 kDa
      Observed band size: 54 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZC3HC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZC3HC1
  • 別名：
    hNIPA antibody; NIPA_HUMAN antibody; Nuclear interacting partner of ALK antibody; Nuclear interacting partner of anaplastic lymphoma kinase antibody; Nuclear-interacting partner of ALK antibody; Nuclear-interacting partner of anaplastic lymphoma kinase antibody; zc3hc1 antibody; Zinc finger C3HC type containing 1 antibody; Zinc finger C3HC-type protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
  • 基因功能參考文獻：
    1. Common nonsynonymous coding variant in ZC3HC1 (rs11556924) is associated with protection from coronary artery disease. PMID: 28115489
    2. This study shows that the Coronary Artery Disease-associated coding polymorphism in ZC3HC1 alters the dynamics of cell-cycle regulation by NIPA. PMID: 27226629
    3. ZC3HC1 rs11556924 polymorphism is associated with hypertension in a Finnish cohort. PMID: 26266351
    4. Results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in rheumatoid arthritis. PMID: 24286297
    5. The NIPA protein is a human F-box-containing protein that defines an SCF-type E3 ligase (SCF(NIPA)) controlling mitotic entry. PMID: 16009132
    6. Data show that cell cycle-dependent phosphorylation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA)is mediated by extracellular signal-regulated kinase 2 (ERK2). PMID: 22955283
    7. phosphorylated NIPA is degraded in late mitosis in an APC/C(Cdh1)-dependent manner PMID: 22205987
    8. NIPA has an antiapoptotic role in NPM-ALK-mediated signaling events PMID: 12748172

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes.
  • 數據庫鏈接：

    HGNC: 29913

    KEGG: hsa:51530

    STRING: 9606.ENSP00000351052

    UniGene: Hs.194157



主站蜘蛛池模板： 久久国产福利国产秒拍| 在线观看国产丝袜控网站| 337p日本欧洲亚洲大胆在线| 亚洲精品综合一区二区| 狠狠色丁香久久婷婷综合蜜芽五月| 欧美老熟妇乱子| 国产亚洲视频中文字幕97精品| 亚洲s码欧洲m码国产av| 精品国产免费第一区二区三区| 无人去码一码二码三码区| 伴郎粗大的内捧猛烈进出视频观看| 小sao货水好多真紧h无码视频| 亚洲色成人网站永久| 精品国产在天天在线观看| 好吊色欧美一区二区三区视频| 久久亚洲一区二区三区四区五区| 免费现黄频在线观看国产| 韩国精品视频一区二区在线播放 | 99视频精品全部免费免费观看| 国产大学生粉嫩无套流白浆| 天天摸夜夜摸夜夜狠狠摸| 无码精品a∨在线观看无广告| 亚洲精品久久yy5099| 国产女人乱子对白av片| 少妇扒开粉嫩小泬视频| 在线亚洲精品国产一区麻豆 | 4hu亚洲人成人无码网www电影首页| 少妇一边呻吟一边说使劲视频| 欧美猛少妇色xxxxx猛叫| 饥渴丰满少妇大力进入| 一本大道大臿蕉视频无码| 亚洲色欲色欱www在线| 人妻洗澡被强公日日澡电影 | 久久99亚洲精品久久99果| 日韩a无v码在线播放| 国产精品免费视频色拍拍| 国产精品一区二区久久国产| 久久se精品一区精品二区| 国产午夜免费高清久久影院| 拍真实国产伦偷精品| 香蕉成人伊视频在线观看|