在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP48 Antibody

  • 中文名稱:
    USP48兔多克隆抗體
  • 貨號:
    CSB-PA070003
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    USP48
  • 別名:
    AAH67261 antibody; Deubiquitinating enzyme 48 antibody; DKFZp762M1713 antibody; EC 3.1.2.15 antibody; Kiaa4202 antibody; MGC132556 antibody; MGC14879 antibody; RAP1GA1 antibody; Synaptic ubiquitin specific protease antibody; synUSP antibody; Ubiquitin carboxyl terminal hydrolase 48 antibody; Ubiquitin carboxyl-terminal hydrolase 48 antibody; Ubiquitin specific peptidase 48 antibody; Ubiquitin specific processing protease 48 antibody; Ubiquitin specific protease 31 antibody; Ubiquitin specific protease 48 antibody; Ubiquitin thioesterase 48 antibody; Ubiquitin thiolesterase 48 antibody; Ubiquitin-specific-processing protease 48 antibody; UBP48_HUMAN antibody; USP31 antibody; USP48 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human USP48.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
  • 基因功能參考文獻:
    1. USP48 inactivation reduces chromosomal instability of Fanconi anemia (FA)-defective cells. Our results highlight a role for USP48 in controlling DNA repair and suggest it as a potential target that could be therapeutically exploited for FA. PMID: 29891926
    2. In contrast to other deubiquitinating enzymes (DUBs) that have been previously implicated in the regulation of Mdm2 protein stability, USP48 did not induce Mdm2 stabilization by significantly reducing Mdm2 ubiquitination levels. PMID: 28233861
    3. down-regulation of USP48 increases E-cadherin expression and epithelial barrier integrity through reducing TRAF2 stability PMID: 28874458
    4. study reveals that the USP48-Gli1 regulatory axis is critical for glioma cell proliferation and glioblastoma tumorigenesis. PMID: 28623188
    5. Data suggest that ubiquitin specific protease-48 (USP48) promotes genome stability by antagonizing BRCA1 E3 ligase function. PMID: 29335415
    6. this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB/RelA in the nucleus. PMID: 25486460
    7. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung. PMID: 15354349
    8. The Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40, LMP1, TRAF2, TRAF6 and IKKbeta-mediated NF-kappaB activation, but did not inhibit Smad-mediated transcription activation. PMID: 16214042
    9. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 expression and function PMID: 24308971

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Peptidase C19 family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 18533

    OMIM: 617445

    KEGG: hsa:84196

    STRING: 9606.ENSP00000309262

    UniGene: Hs.467524



主站蜘蛛池模板: 成人h无码动漫超w网站| 精品综合久久久久久8888| 成人无码一区二区三区网站| 三级特黄60分钟在线观看| 国产成人精品999在线观看| 99久久国产露脸国语对白| 久久精品无码一区二区日韩av| 好男人日本社区www| 亚洲中文无码av永久伊人| 亚洲成成熟女人专区| 一本一道av无码中文字幕﹣百度| 人妻久久久一区二区三区| 日韩精品久久久肉伦网站| 久久中文精品无码中文字幕| 亚洲 日韩 国产 有码 不卡| 欧美另类精品xxxx| 久久国产成人午夜av影院| 欧美乱码精品一区二区三区| 久久天天躁狠狠躁夜夜躁2012| 国产亚洲色欲色一色www| 亚洲日韩国产精品第一页一区| 国产激情久久久久久熟女老人av | 国产精品 视频一区 二区三区| 99在线精品免费视频| 四虎永久在线精品免费视频观看| 亚洲欧美综合成人五月天网站| 亚洲色精品88色婷婷七月丁香 | 亚洲中文字幕在线观看| 很色很爽很黄裸乳视频| 人人爽人人爽人人片av东京热| 国产偷国产偷亚洲清高孕妇| 四虎永久在线精品免费网站| 国产欧美日韩精品a在线观看| 青青青国产免a在线观看| 大屁股熟女白浆一区二区| 人人爽人人爽人人片av亚洲| ww国产内射精品后入国产| 国产精品综合一区二区三区| 亚洲最大成人网 色香蕉| 天天干天天日夜夜操| 色又黄又爽18禁免费网站现观看 |