在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP48 Antibody, FITC conjugated

  • 中文名稱:
    USP48兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA774808LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) USP48 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    USP48
  • 別名:
    AAH67261 antibody; Deubiquitinating enzyme 48 antibody; DKFZp762M1713 antibody; EC 3.1.2.15 antibody; Kiaa4202 antibody; MGC132556 antibody; MGC14879 antibody; RAP1GA1 antibody; Synaptic ubiquitin specific protease antibody; synUSP antibody; Ubiquitin carboxyl terminal hydrolase 48 antibody; Ubiquitin carboxyl-terminal hydrolase 48 antibody; Ubiquitin specific peptidase 48 antibody; Ubiquitin specific processing protease 48 antibody; Ubiquitin specific protease 31 antibody; Ubiquitin specific protease 48 antibody; Ubiquitin thioesterase 48 antibody; Ubiquitin thiolesterase 48 antibody; Ubiquitin-specific-processing protease 48 antibody; UBP48_HUMAN antibody; USP31 antibody; USP48 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 48 protein (358-508AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
  • 基因功能參考文獻:
    1. USP48 inactivation reduces chromosomal instability of Fanconi anemia (FA)-defective cells. Our results highlight a role for USP48 in controlling DNA repair and suggest it as a potential target that could be therapeutically exploited for FA. PMID: 29891926
    2. In contrast to other deubiquitinating enzymes (DUBs) that have been previously implicated in the regulation of Mdm2 protein stability, USP48 did not induce Mdm2 stabilization by significantly reducing Mdm2 ubiquitination levels. PMID: 28233861
    3. down-regulation of USP48 increases E-cadherin expression and epithelial barrier integrity through reducing TRAF2 stability PMID: 28874458
    4. study reveals that the USP48-Gli1 regulatory axis is critical for glioma cell proliferation and glioblastoma tumorigenesis. PMID: 28623188
    5. Data suggest that ubiquitin specific protease-48 (USP48) promotes genome stability by antagonizing BRCA1 E3 ligase function. PMID: 29335415
    6. this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB/RelA in the nucleus. PMID: 25486460
    7. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung. PMID: 15354349
    8. The Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40, LMP1, TRAF2, TRAF6 and IKKbeta-mediated NF-kappaB activation, but did not inhibit Smad-mediated transcription activation. PMID: 16214042
    9. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 expression and function PMID: 24308971

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Peptidase C19 family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 18533

    OMIM: 617445

    KEGG: hsa:84196

    STRING: 9606.ENSP00000309262

    UniGene: Hs.467524



主站蜘蛛池模板: 亚洲色精品三区二区一区| 东京热毛片无码dvd一二三区| 日本丰满岳乱妇在线观看| 亚洲综合另类小说色区大陆| 国产普通话对白刺激| 国产va在线观看免费| 日韩精品无码一区二区忘忧草| 久久天天躁狠狠躁夜夜2020老熟妇 | 国产无遮挡a片又黄又爽漫画| 小鲜肉自慰网站| 免费观看又色又爽又黄的韩国 | 欧美中文字幕无线码视频| 人妻av乱片av出轨av| 亚洲另类春色校园小说| www国产亚洲精品久久网站| 怡红院免费的全部视频| 精品亚洲成a人在线观看青青 | 99精品国产在热久久| 真实国产精品vr专区| 18禁又污又黄又爽的网站不卡| 日本丰满熟妇videossex8k | 欧美乱色伦图片区| 性夜影院午夜看片| 久久久久久综合岛国免费观看| 亚洲最大成人网站| 免费的很黄很污的视频| 国产精品一区二区在线蜜芽tv| 131美女爱做视频国产福利| 日韩网红少妇无码视频香港| 少妇熟女高潮流白浆| 亚洲熟妇无码av| 99精品国产在热久久无码| 国产偷窥熟精品视频| 亚洲午夜久久久精品影院| 久久精品国产精品亚洲| 色综合色狠狠天天综合网| 一中文字幕日产乱码va| 成人免费一区二区三区| 亚洲aⅴ在线无码天堂777| 野外性史欧美k8播放| 国产精品亚洲一区二区三区在线|