在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ubiquitin carboxyl-terminal hydrolase 48 (USP48), partial

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 48 (USP48), partial

  • 中文名稱：
    人USP48重組蛋白
  • 貨號(hào)：
    CSB-YP774808HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人USP48重組蛋白
  • 貨號(hào)：
    CSB-EP774808HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人USP48重組蛋白
  • 貨號(hào)：
    CSB-EP774808HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人USP48重組蛋白
  • 貨號(hào)：
    CSB-BP774808HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人USP48重組蛋白
  • 貨號(hào)：
    CSB-MP774808HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    USP48
  • Uniprot No.：
  • 別名：
    AAH67261; Deubiquitinating enzyme 48; DKFZp762M1713; EC 3.1.2.15; Kiaa4202; MGC132556; MGC14879; RAP1GA1; Synaptic ubiquitin specific protease; synUSP; Ubiquitin carboxyl terminal hydrolase 48; Ubiquitin carboxyl-terminal hydrolase 48; Ubiquitin specific peptidase 48; Ubiquitin specific processing protease 48; Ubiquitin specific protease 31; Ubiquitin specific protease 48; Ubiquitin thioesterase 48; Ubiquitin thiolesterase 48; Ubiquitin-specific-processing protease 48; UBP48_HUMAN; USP31; USP48
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
  • 基因功能參考文獻(xiàn)：
    1. USP48 inactivation reduces chromosomal instability of Fanconi anemia (FA)-defective cells. Our results highlight a role for USP48 in controlling DNA repair and suggest it as a potential target that could be therapeutically exploited for FA. PMID: 29891926
    2. In contrast to other deubiquitinating enzymes (DUBs) that have been previously implicated in the regulation of Mdm2 protein stability, USP48 did not induce Mdm2 stabilization by significantly reducing Mdm2 ubiquitination levels. PMID: 28233861
    3. down-regulation of USP48 increases E-cadherin expression and epithelial barrier integrity through reducing TRAF2 stability PMID: 28874458
    4. study reveals that the USP48-Gli1 regulatory axis is critical for glioma cell proliferation and glioblastoma tumorigenesis. PMID: 28623188
    5. Data suggest that ubiquitin specific protease-48 (USP48) promotes genome stability by antagonizing BRCA1 E3 ligase function. PMID: 29335415
    6. this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB/RelA in the nucleus. PMID: 25486460
    7. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung. PMID: 15354349
    8. The Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40, LMP1, TRAF2, TRAF6 and IKKbeta-mediated NF-kappaB activation, but did not inhibit Smad-mediated transcription activation. PMID: 16214042
    9. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 expression and function PMID: 24308971

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase C19 family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18533

    OMIM: 617445

    KEGG: hsa:84196

    STRING: 9606.ENSP00000309262

    UniGene: Hs.467524



主站蜘蛛池模板： 人人人妻人人澡人人爽欧美一区| 女人高潮流白浆视频| 国产永久免费观看视频| 中文字幕久久综合伊人| 男女车车的车车网站w98免费 | 丰满少妇人妻hd高清大乳在线| 两性色午夜视频免费无码| 538在线精品视频| 男女裸交免费无遮挡全过程| 精品无码欧美黑人又粗又| 欧产日产国产精品| 四虎成人精品永久网站| 成人综合婷婷国产精品久久蜜臀| 国产农村妇女精品一二区| 精品玖玖玖视频在线观看| 伊人久久大香线蕉综合bd高清| 夜夜爽妓女8888888视频| 欧美日韩亚洲国产精品| aaaaa少妇高潮大片| 先锋人妻无码av电影| 亚洲午夜成人精品无码| 国产成人av一区二区在线观看| 无码av高潮抽搐流白浆| 真实国产乱子伦对白视频不卡 | 日本高清视频网站www| 亚洲精品无码久久久久yw | 久久久久免费看黄a片app| 久久www免费人成精品| 狠狠色综合久久丁香婷婷| 牲高潮99爽久久久久777| 玩弄白嫩少妇xxxxx性| 成在线人免费视频一区二区| 曰本极品少妇videossexhd| 国产精品无需播放器在线观看| 三上悠亚ssⅰn939无码播放| 国产人成视频在线视频| 国产成人手机高清在线观看网站| 67194熟妇在线直接进入| 欧美牲交40_50a欧美牲交aⅴ| 无码人妻丰满熟妇区五十路| 18成禁人视频免费|