在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. USP24 Antibody

USP24 Antibody

  • 中文名稱：
    USP24兔多克隆抗體
  • 貨號：
    CSB-PA890777LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA890777LA01HU diluted at 1:200 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA890777LA01HU diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) USP24 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    USP24
  • 別名：
    Deubiquitinating enzyme 24 antibody; KIAA1057 antibody; Ubiquitin carboxyl terminal hydrolase 24 antibody; Ubiquitin carboxyl-terminal hydrolase 24 antibody; Ubiquitin specific peptidase 24 antibody; Ubiquitin specific processing protease 24 antibody; Ubiquitin specific protease 24 antibody; Ubiquitin thioesterase 24 antibody; Ubiquitin thiolesterase 24 antibody; Ubiquitin-specific-processing protease 24 antibody; UBP24_HUMAN antibody; Usp24 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 24 protein (2509-2620AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，USP24 Antibody (CSB-PA890777LA01HU)，的標記方式是Non-conjugated。對于USP24 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA890777LB01HU USP24 Antibody, HRP conjugated ELISA
    FITC CSB-PA890777LC01HU USP24 Antibody, FITC conjugated
    Biotin CSB-PA890777LD01HU USP24 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
  • 基因功能參考文獻：
    1. USP24 level was decreased during the early stage of cancer and the mitotic stage of the cell cycle to regulate its substrates p300, Bax, E2F4 and securin, resulting in decreased cell apoptosis and increased cell cycle progression and, thus, cancer formation. PMID: 27991932
    2. Data show that ubiquitin-specific peptidase 24 (USP24) is highly expressed in cell lines with enhanced malignancy and in late-stage lung cancer clinical samples. PMID: 26568301
    3. USP24 deubiquitinase regulates the DNA damage response by directly targeting the p53 tumor suppressor. PMID: 25578727
    4. the novel compound EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice. PMID: 25814533
    5. These results suggested that USP24 expression is tightly regulated at its transcription level and NFkappaB plays an important role in this process. PMID: 24286619
    6. The knockdown of USP24 in two human cell lines decreased the steady-state levels of DDB2, indicating that USP24-mediated DDB2 deubiquitination prevents DDB2 degradation. PMID: 23159851
    7. The present study is the first to report a lack of association between SNPs of USP24 and parkinson disease in Han Chinese patients. Other PMID: 22923019
    8. USP24 alone plays a role in PD susceptibility among Taiwanese people >or=60 years of age, or acting synergistically with USP40 and UCHL1 in the total subjects. PMID: 20302855
    9. Data suggest that genetic variants in USP24 affect the risk for late-onset Parkinson disease (PD), which is consistent with the predicted role of the ubiquitination pathway in PD etiology. PMID: 16917932

    顯示更多

    收起更多

  • 蛋白家族：
    Peptidase C19 family
  • 數據庫鏈接：

    HGNC: 12623

    OMIM: 610569

    KEGG: hsa:23358

    STRING: 9606.ENSP00000294383

    UniGene: Hs.477009



主站蜘蛛池模板： 成人免费无码大片a毛片抽搐| 欧美亚洲日本国产黑白配| 乱子伦农村xxxxbbb| 男女下面一进一出无遮挡 | 久久国产欧美成人网站| 中国china露脸自拍性hd| 57pao成人国产永久免费视频| 丰满岳乱妇在线观看中字 | 国产色视频一区二区三区qq号| 人妻教师痴汉电车波多野结衣| 免费永久看黄神器无码软件| 午夜爽爽爽男女免费观看影院| 青青草视频在线观看| 男女啪祼交视频| 青青草国产精品欧美成人| 日韩成人av无码一区二区三区| 亚欧免费无码aⅴ在线观看 | 国产精品免费福利久久| 内射毛片内射国产夫妻| 国产女精品视频网站免费| 强制高潮18xxxxhd日韩| 亚洲色欲色欱www在线| 无翼乌工口肉肉无遮挡无码18| 337p日本大胆欧久久| 午夜嘿嘿嘿影院| 女性女同性aⅴ免费观女性恋| 国产爆乳无码视频在线观看| 国内精品自在自线视频| 欧洲美熟女乱又伦| 国产欧美久久一区二区三区| 亚洲视频无码高清在线| av无码免费岛国动作片不卡| 永久黄网站色视频免费| 日韩精品人妻系列一区二区三区| 国产亚洲精品视觉盛宴| 亚洲一区二区三区影院| 日日噜噜夜夜狠狠久久丁香五月| 中文字幕日韩人妻不卡一区| 欧美成人一区二区三区在线观看| 国产成人人人97超碰超爽8| 小12萝裸体自慰出白浆|