在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP24 Antibody, HRP conjugated

  • 中文名稱:
    USP24兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA890777LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) USP24 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    USP24
  • 別名:
    Deubiquitinating enzyme 24 antibody; KIAA1057 antibody; Ubiquitin carboxyl terminal hydrolase 24 antibody; Ubiquitin carboxyl-terminal hydrolase 24 antibody; Ubiquitin specific peptidase 24 antibody; Ubiquitin specific processing protease 24 antibody; Ubiquitin specific protease 24 antibody; Ubiquitin thioesterase 24 antibody; Ubiquitin thiolesterase 24 antibody; Ubiquitin-specific-processing protease 24 antibody; UBP24_HUMAN antibody; Usp24 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 24 protein (2509-2620AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
  • 基因功能參考文獻:
    1. USP24 level was decreased during the early stage of cancer and the mitotic stage of the cell cycle to regulate its substrates p300, Bax, E2F4 and securin, resulting in decreased cell apoptosis and increased cell cycle progression and, thus, cancer formation. PMID: 27991932
    2. Data show that ubiquitin-specific peptidase 24 (USP24) is highly expressed in cell lines with enhanced malignancy and in late-stage lung cancer clinical samples. PMID: 26568301
    3. USP24 deubiquitinase regulates the DNA damage response by directly targeting the p53 tumor suppressor. PMID: 25578727
    4. the novel compound EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice. PMID: 25814533
    5. These results suggested that USP24 expression is tightly regulated at its transcription level and NFkappaB plays an important role in this process. PMID: 24286619
    6. The knockdown of USP24 in two human cell lines decreased the steady-state levels of DDB2, indicating that USP24-mediated DDB2 deubiquitination prevents DDB2 degradation. PMID: 23159851
    7. The present study is the first to report a lack of association between SNPs of USP24 and parkinson disease in Han Chinese patients. Other PMID: 22923019
    8. USP24 alone plays a role in PD susceptibility among Taiwanese people >or=60 years of age, or acting synergistically with USP40 and UCHL1 in the total subjects. PMID: 20302855
    9. Data suggest that genetic variants in USP24 affect the risk for late-onset Parkinson disease (PD), which is consistent with the predicted role of the ubiquitination pathway in PD etiology. PMID: 16917932

    顯示更多

    收起更多

  • 蛋白家族:
    Peptidase C19 family
  • 數據庫鏈接:

    HGNC: 12623

    OMIM: 610569

    KEGG: hsa:23358

    STRING: 9606.ENSP00000294383

    UniGene: Hs.477009



主站蜘蛛池模板: 丁香婷婷无码不卡在线| 国产乱码一区二区三区爽爽爽| 国产乱人伦av在线麻豆a| 久久天天躁狠狠躁夜夜2019| 欧美日韩中文国产一区发布| 免费人妻av无码专区| 亚洲国产成人精品久久久| 天天爽夜夜爽人人爽从早干到睌| 又黄又湿啪啪响18禁| av无码免费岛国动作片不卡| 亚洲综合图色40p| 国产sm主人调教女m视频| 国产福利高颜值在线观看| 狠狠色噜噜狠狠狠狠米奇777| 丰满岳妇乱一区二区三区| 久久久久成人精品免费播放动漫 | 国产成人mv视频在线观看| 精品亚洲成av人在线观看| 久久久久99精品成人片| 中国亚洲女人69内射少妇| 无码人妻aⅴ一区二区三区有奶水| 亚洲va天堂va欧美ⅴa在线| 国产精品久久人妻互换| 国产精品久久欧美久久一区| 亚洲午夜无码av毛片久久| 欲色影视天天一区二区三区色香欲 | 天天做天天大爽天天爱| 免费视频国产在线观看| 欧美xxxx黑人又粗又长| 欧美伊人久久大香线蕉综合| 996久久国产精品线观看| 2019久久视频这里有精品15| 亚洲 日韩 国产欧美 另类| 亚洲人成电影网站色www| 国产婷婷成人久久av免费高清| 国产精品午夜福利不卡120| 亚洲a∨精品一区二区三区| 天天爽夜夜爽人人爽| 亚洲va久久久噜噜噜久久狠狠| 欧美性猛交xxx嘿人猛交| 亚洲人成电影在线天堂色|