在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP24 Antibody, HRP conjugated

  • 中文名稱:
    USP24兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA890777LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) USP24 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    USP24
  • 別名:
    Deubiquitinating enzyme 24 antibody; KIAA1057 antibody; Ubiquitin carboxyl terminal hydrolase 24 antibody; Ubiquitin carboxyl-terminal hydrolase 24 antibody; Ubiquitin specific peptidase 24 antibody; Ubiquitin specific processing protease 24 antibody; Ubiquitin specific protease 24 antibody; Ubiquitin thioesterase 24 antibody; Ubiquitin thiolesterase 24 antibody; Ubiquitin-specific-processing protease 24 antibody; UBP24_HUMAN antibody; Usp24 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 24 protein (2509-2620AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
  • 基因功能參考文獻:
    1. USP24 level was decreased during the early stage of cancer and the mitotic stage of the cell cycle to regulate its substrates p300, Bax, E2F4 and securin, resulting in decreased cell apoptosis and increased cell cycle progression and, thus, cancer formation. PMID: 27991932
    2. Data show that ubiquitin-specific peptidase 24 (USP24) is highly expressed in cell lines with enhanced malignancy and in late-stage lung cancer clinical samples. PMID: 26568301
    3. USP24 deubiquitinase regulates the DNA damage response by directly targeting the p53 tumor suppressor. PMID: 25578727
    4. the novel compound EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice. PMID: 25814533
    5. These results suggested that USP24 expression is tightly regulated at its transcription level and NFkappaB plays an important role in this process. PMID: 24286619
    6. The knockdown of USP24 in two human cell lines decreased the steady-state levels of DDB2, indicating that USP24-mediated DDB2 deubiquitination prevents DDB2 degradation. PMID: 23159851
    7. The present study is the first to report a lack of association between SNPs of USP24 and parkinson disease in Han Chinese patients. Other PMID: 22923019
    8. USP24 alone plays a role in PD susceptibility among Taiwanese people >or=60 years of age, or acting synergistically with USP40 and UCHL1 in the total subjects. PMID: 20302855
    9. Data suggest that genetic variants in USP24 affect the risk for late-onset Parkinson disease (PD), which is consistent with the predicted role of the ubiquitination pathway in PD etiology. PMID: 16917932

    顯示更多

    收起更多

  • 蛋白家族:
    Peptidase C19 family
  • 數據庫鏈接:

    HGNC: 12623

    OMIM: 610569

    KEGG: hsa:23358

    STRING: 9606.ENSP00000294383

    UniGene: Hs.477009



主站蜘蛛池模板: 欧美野外疯狂做受xxxx高潮| 人妻换人妻仑乱| 午夜裸体性播放| 樱花草在线社区www中国中文| 亚洲深深色噜噜狠狠爱网站| 国产三级在线观看免费| 亚洲中文字幕久久精品蜜桃| 国产亚洲精品一区二三区| 色诱久久久久综合网ywww| 少妇人妻真实偷人精品视频| 2018国产大陆天天弄| 少妇人妻综合久久中文字幕| 日本三级香港三级人妇三| 男生白内裤自慰gv白袜男同| 成 人 网 站 免费观看| 亚洲综合天堂av网站在线观看| 亚洲日本va中文字幕| 久久先锋男人av资源网站| 丁香五月缴情在线| 国产+成+人+亚洲欧洲自线| 国产精品成人午夜久久| 夜夜高潮夜夜爽夜夜爱| 亚洲精品国产品国语在线| 亚洲中文字幕无码mv | 亚洲成a人v欧美综合天堂下载| 性av无码天堂vr专区| 久久综合香蕉国产蜜臀av| 国产日产欧产美| 久久成人国产精品无码| 欧美另类精品xxxx人妖| 玩弄白嫩少妇xxxxx性| 免费观看激色视频网站| 成年网站未满十八禁视频天堂 | 亚洲精品综合在线影院| 中文天堂最新版资源www官网| 国产精品久久久久久久久久免费看 | 成人免费大片黄在线观看com| 亚洲人成人无码www影院| 男人扒女人添高潮视频| 交换交换乱杂烩系列yy| 亚洲高清乱码午夜电影网制服|