在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP24 Antibody, FITC conjugated

  • 中文名稱:
    USP24兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA890777LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) USP24 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    USP24
  • 別名:
    Deubiquitinating enzyme 24 antibody; KIAA1057 antibody; Ubiquitin carboxyl terminal hydrolase 24 antibody; Ubiquitin carboxyl-terminal hydrolase 24 antibody; Ubiquitin specific peptidase 24 antibody; Ubiquitin specific processing protease 24 antibody; Ubiquitin specific protease 24 antibody; Ubiquitin thioesterase 24 antibody; Ubiquitin thiolesterase 24 antibody; Ubiquitin-specific-processing protease 24 antibody; UBP24_HUMAN antibody; Usp24 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 24 protein (2509-2620AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
  • 基因功能參考文獻:
    1. USP24 level was decreased during the early stage of cancer and the mitotic stage of the cell cycle to regulate its substrates p300, Bax, E2F4 and securin, resulting in decreased cell apoptosis and increased cell cycle progression and, thus, cancer formation. PMID: 27991932
    2. Data show that ubiquitin-specific peptidase 24 (USP24) is highly expressed in cell lines with enhanced malignancy and in late-stage lung cancer clinical samples. PMID: 26568301
    3. USP24 deubiquitinase regulates the DNA damage response by directly targeting the p53 tumor suppressor. PMID: 25578727
    4. the novel compound EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice. PMID: 25814533
    5. These results suggested that USP24 expression is tightly regulated at its transcription level and NFkappaB plays an important role in this process. PMID: 24286619
    6. The knockdown of USP24 in two human cell lines decreased the steady-state levels of DDB2, indicating that USP24-mediated DDB2 deubiquitination prevents DDB2 degradation. PMID: 23159851
    7. The present study is the first to report a lack of association between SNPs of USP24 and parkinson disease in Han Chinese patients. Other PMID: 22923019
    8. USP24 alone plays a role in PD susceptibility among Taiwanese people >or=60 years of age, or acting synergistically with USP40 and UCHL1 in the total subjects. PMID: 20302855
    9. Data suggest that genetic variants in USP24 affect the risk for late-onset Parkinson disease (PD), which is consistent with the predicted role of the ubiquitination pathway in PD etiology. PMID: 16917932

    顯示更多

    收起更多

  • 蛋白家族:
    Peptidase C19 family
  • 數據庫鏈接:

    HGNC: 12623

    OMIM: 610569

    KEGG: hsa:23358

    STRING: 9606.ENSP00000294383

    UniGene: Hs.477009



主站蜘蛛池模板: 午夜福利无码不卡在线观看| 色六月婷婷亚洲婷婷六月 | 久久精品国产亚洲不av麻豆| 国产伦久视频免费观看视频| 日本极品少妇xxxx| 正在播放国产真实哭都没用| 日韩精品专区在线影院重磅 | 亚洲日韩乱码中文无码蜜桃臀| 亚洲的天堂av无码| 日韩卡1卡2 卡三卡免费| 国产亚洲精品久久一区二区 | 四虎影视成人永久免费观看视频| 久久久久国产精品人妻aⅴ毛片| 免费国产黄网站在线观看可以下载| 少妇人妻偷人激情视频| 2020无码专区人妻系列日韩| 国产女人高潮嗷嗷嗷叫| 欧美精品中文字幕在线视| 青青草原综合久久大伊人精品| 国产午夜成人av在线播放| 国产一区二区三区精品av| 亚洲综合久久成人a片| 久久久久无码国产精品一区| 成年无码动漫av片在线观看羞羞| 97久久超碰精品视觉盛宴| 曰韩无码二三区中文字幕| 国产思思99re99在线观看| 国产ae86亚洲福利入口| 亚洲男人的天堂在线aⅴ视频| 狠狠97人人婷婷五月| 国产高清japanese在线播放e| 婷婷激情综合色五月久久竹菊影视 | 久久精品99久久香蕉国产色戒| 国产亚洲视频在线播放香蕉| 无码人妻日韩一区日韩二区| 亚洲欧洲中文日韩久久av乱码| 中文在线а√天堂官网| 狠狠色老熟妇老熟女| 国产乱理伦片在线观看| 天天爽夜夜爽夜夜爽精品视频| 亚洲人成网线在线播放|