在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UBE3C Antibody, FITC conjugated

UBE3C Antibody, FITC conjugated

  • 中文名稱：
    UBE3C兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA621871LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UBE3C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    HectH2 antibody; KIAA0010 antibody; KIAA10 antibody; Ube3c antibody; UBE3C_HUMAN antibody; Ubiquitin protein isopeptide ligase (E3) antibody; Ubiquitin protein ligase E3C antibody; Ubiquitin-protein ligase E3C antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
  • 基因功能參考文獻(xiàn)：
    1. miR-542-3p functioned as a tumor suppressor gene in regulating the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma via targeting UBE3C. PMID: 28666208
    2. UBE3C promotes melanoma progression, possibly by inducing epithelial-mesenchymal transition in melanoma cells PMID: 26894856
    3. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy. PMID: 26067607
    4. these observations suggest that UBE3C plays an important role in RCC development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC. PMID: 25658088
    5. UBE3C is a mutant candidate oncogene involved in tumor development and progression of hepatocellular carcinoma. PMID: 24425307
    6. knockdown renders cells more susceptible to the Hsp90 inhibitor 17-AAG, suggesting that UBE3C protects against the harmful accumulation of protein fragments arising from incompletely degraded proteasome substrates. PMID: 24158444
    7. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics. PMID: 21881582
    8. negatively regulates type I interferon through ubiquitination of the transcription factors PMID: 21167755
    9. gene polymorphism is associated with the risk of Aspirin-intolerant asthma PMID: 20934631
    10. TIP120B is a specific substrate of KIAA10; both are highly expressed in human skeletal muscle, suggesting that KIAA10 may regulate TIP120B homeostasis specifically in this tissue. PMID: 12692129

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16803

    OMIM: 614454

    KEGG: hsa:9690

    STRING: 9606.ENSP00000309198

    UniGene: Hs.118351



主站蜘蛛池模板： 久久精品九九亚洲精品天堂| 国产男女猛烈无遮挡免费网站| 成人区人妻精品一区二区不卡视频| 国产影片av级毛片特别刺激| 国产成人美女视频网站| 少妇高潮太爽了在线观看欧美| 欧美老妇人与禽交| 国产一区二区三区四区五区加勒比| 欧美 国产日韩 综合在线| 午夜成人影院网站18进| 18禁黄久久久aaa片| 天天天天躁天天爱天天碰2018| 亚洲国产精品特色大片观看完整版| 久久午夜夜伦鲁鲁片免费无码影视| 无遮无挡爽爽免费视频| 日韩中文字幕在线专区| 又大又粗弄得我出好多水| 亚洲乱码国产乱码精品精大量| 双腿高潮抽搐喷白浆视频| 伊人久久精品av一区二区| 色噜噜一区二区三区| 精品国内自产拍在线观看视频| 狠人干练合综合网| 国产婷婷综合在线视频| 国产精品久久久久久久久久久久人四虎| 国内精品国产三级国产av| 久久中文字幕乱码久久午夜| 国产精品久久精品第一页| 国产97色在线 | 亚洲| 亚洲欧美日韩成人综合网| 日本一丰满一bbw| 欧精国精产品一区| 人妻奶水人妻系列| 久久精品国产亚洲欧美成人| 最新无码a∨在线观看| av天堂午夜精品一区| 无码国内精品人妻少妇| 天堂网www天堂资源网| 无码国产成人午夜电影在线观看 | 天堂av男人在线播放| 伊人成伊人成综合网222|