在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UBE3C Antibody, Biotin conjugated

UBE3C Antibody, Biotin conjugated

  • 中文名稱：
    UBE3C兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA621871LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UBE3C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    HectH2 antibody; KIAA0010 antibody; KIAA10 antibody; Ube3c antibody; UBE3C_HUMAN antibody; Ubiquitin protein isopeptide ligase (E3) antibody; Ubiquitin protein ligase E3C antibody; Ubiquitin-protein ligase E3C antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
  • 基因功能參考文獻：
    1. miR-542-3p functioned as a tumor suppressor gene in regulating the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma via targeting UBE3C. PMID: 28666208
    2. UBE3C promotes melanoma progression, possibly by inducing epithelial-mesenchymal transition in melanoma cells PMID: 26894856
    3. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy. PMID: 26067607
    4. these observations suggest that UBE3C plays an important role in RCC development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC. PMID: 25658088
    5. UBE3C is a mutant candidate oncogene involved in tumor development and progression of hepatocellular carcinoma. PMID: 24425307
    6. knockdown renders cells more susceptible to the Hsp90 inhibitor 17-AAG, suggesting that UBE3C protects against the harmful accumulation of protein fragments arising from incompletely degraded proteasome substrates. PMID: 24158444
    7. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics. PMID: 21881582
    8. negatively regulates type I interferon through ubiquitination of the transcription factors PMID: 21167755
    9. gene polymorphism is associated with the risk of Aspirin-intolerant asthma PMID: 20934631
    10. TIP120B is a specific substrate of KIAA10; both are highly expressed in human skeletal muscle, suggesting that KIAA10 may regulate TIP120B homeostasis specifically in this tissue. PMID: 12692129

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
  • 數據庫鏈接：

    HGNC: 16803

    OMIM: 614454

    KEGG: hsa:9690

    STRING: 9606.ENSP00000309198

    UniGene: Hs.118351



主站蜘蛛池模板： 夜晚被公侵犯的人妻深田字幕| 国产精品亲子乱子伦xxxx裸| 成人欧美一区二区三区黑人免费 | 国产成人av大片大片在线播放| 色噜噜狠狼综合在线| 亚洲精品tv久久久久久久久j| 男女下面一进一出无遮挡| 2019nv天堂香蕉在线观看| 亚洲精品国产一区二区| 亚洲第一极品精品无码| 日韩国产精品人妻无码久久久| 国产在线观看无码免费视频| 90后极品粉嫩小泬20p| 好了av四色综合无码久久| 丁香五月网久久综合| 国产精品va无码免费| 国产精品久久久久7777| 日本一区二区a√成人片| 午夜大片男女免费观看爽爽爽尤物| 偷偷色噜狠狠狠狠的777米奇| 欧美激情精品久久久久久| 亚洲精品久久yy5099| 久久综合狠狠综合久久激情| 少妇下面好紧好多水真爽播放| 漂亮人妻熟睡中被公侵犯中文版| 狠狠色狠狠色狠狠五月| 亚洲中文字幕久久精品无码喷水| 中文字幕乱码亚洲精品一区| 日韩精品无码人妻一区二区三区| 大战丰满无码人妻50p| 女被男啪到哭的视频网站| 精品国产杨幂在线观看| 亚洲国产aⅴ综合网| 韩国日本三级在线观看| 亚洲精品美女久久久久99| 国产成熟妇女性视频电影| 自拍偷自拍亚洲精品情侣| 国产激情久久久久影院老熟女免费| 女人扒下裤让男人桶到爽| 内射合集对白在线| 少妇精品无码一区二区三区|