在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TSC22D1 Antibody, FITC conjugated

  • 中文名稱:
    TSC22D1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA623011LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TSC22D1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TSC22D1
  • 別名:
    Cerebral protein 2 antibody; DKFZp686O19206 antibody; Hucep 2 antibody; Hucep2 antibody; KIAA1994 antibody; MGC17597 antibody; OTTHUMP00000040978 antibody; Ptg 2 antibody; Regulatory protein TSC 22 antibody; Regulatory protein TSC-22 antibody; Regulatory protein TSC22 antibody; RP11 269C23.2 antibody; T22D1_HUMAN antibody; TGFB stimulated clone 22 homolog antibody; TGFB-stimulated clone 22 homolog antibody; TGFB1I4 antibody; TGFbeta stimulated clone 22 antibody; Transcriptional regulator TSC 22 antibody; Transforming growth factor beta 1 induced transcript 4 antibody; Transforming growth factor beta 1 induced transcript 4 protein antibody; Transforming growth factor beta stimulated protein TSC 22 antibody; Transforming growth factor beta-1-induced transcript 4 protein antibody; TSC 22 antibody; TSC22 antibody; TSC22 domain family 1 isoform 2 antibody; TSC22 domain family member 1 antibody; TSC22 domain family protein 1 antibody; TSC22D1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TSC22 domain family protein 1 protein (1-144AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
  • 基因功能參考文獻:
    1. TSC22 could suppress tumor by inhibiting cell proliferation in colorectal cancer cell lines. Multivariate Cox regression analysis confirmed TSC22 expression as independent predictors of the OS in CRC patients PMID: 29481799
    2. TSC-22 acts as a tumor suppressor by safeguarding p53 from poly-ubiquitination mediated-degradation. PMID: 22870275
    3. we report that induced Tsc-22 leads to enhancement of TGF-beta-dependent signaling and enhancement is blocked by expression of a dominant-negative Tsc-22 mutant PMID: 21881999
    4. Differential regulation of antagonistic TSC22D1 variants is required for the establishment of oncogene-induced cellular senescence. PMID: 21448135
    5. Results support role of TSC22D1 as an enhancer of CNP transcription and suggest that TGF-beta-induced upregulation of CNP expression in smooth muscle may be mediated in part by increased transcription of TSC22D1. PMID: 20802130
    6. Long form of TSC22DF is evolutionarily conserved and has growth-regulating potential. PMID: 20149264
    7. Leucine Zipper structure of TSC22 markedly inhibits the anchorage independent growth of salivary gland cancer cells PMID: 11836610
    8. TSC-22 is an important downstream component of PPARgamma and TGF-beta signaling during intestinal epithelial cell differentiation PMID: 12468551
    9. findings suggest that the TSC-22 gene (-396) A allele is associated with an increasing risk of diabetic nephropathy PMID: 12757981
    10. Upregulation of TSC-22 mRNA by TGF-beta 1 is achieved by mRNA stabilization. PMID: 12767908
    11. Tsc-22 modulates the TGF-beta-dependant signaling pathway and binds to and modulate the transcriptional activity of Smad3 and Smad4. It has effect on cellular differentiation PMID: 15881652
    12. expression of TSC-22 in prostate is restricted to basal layer; maybe useful marker for differentation between normal and malignant acinar epithelium of prostate PMID: 16106424
    13. TSC-22 is a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD PMID: 17690703
    14. Expression of TSC-22 was frequently observed in the tumor cells with differentiated-phenotypes, although rarely in the cells with growing potentials. PMID: 18288391
    15. interaction between fortilin and TSC-22 prevents apoptosis via the destabilization of TSC-22 in ovarian carcinoma cells PMID: 18325344

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    TSC-22/Dip/Bun family
  • 組織特異性:
    Widely expressed in fetal and adult tissues.
  • 數據庫鏈接:

    HGNC: 16826

    OMIM: 607715

    KEGG: hsa:8848

    STRING: 9606.ENSP00000397435

    UniGene: Hs.436383



主站蜘蛛池模板: 亚洲日韩久久综合中文字幕| 五月婷婷久久草| 亚洲成a∧人片在线播放调教| 久久久久99精品成人片三人毛片| 亚洲午夜久久久久久久久电影网| 国产清纯白嫩初高生在线观看| 无码人妻丝袜视频在线播免费| 国产激情一区二区三区| 国产精品户外野外| 日本丰满熟妇videossex| 免费大片av手机看片不卡| 国产又色又爽又黄的免费| 欧美午夜特黄aaaaaa片| 亚洲综合色婷婷七月丁香| 日99久9在线 | 免费| 2018高清国产一区二区三区| 东京热久久综合久久88| 最大胆裸体人体牲交| 国产午夜成人无码免费看不卡| 蜜桃麻豆www久久国产sex| 国产成人精品视频ⅴa片软件竹菊| 亚洲精品国产电影| 国产成人啪精品视频免费网站软件| 亚洲无线码一区二区三区| 麻豆一区二区99久久久久| 巨胸美乳无码人妻视频| а√天堂www在线а√天堂资源| 亚洲欧洲日产国码无码| 成人无码av片在线观看| 女人18毛片水真多免费看| 亚洲成在人网站无码天堂| 亚洲国产精华液网站w| 日本三级韩国三级欧美三级| 精品一卡二卡三卡四卡网站| 精品一卡2卡三卡4卡免费网站| 国产美女极度色诱视频www| 亚洲夜色噜噜av在线观看 | 无码精品一区二区三区免费视频 | 女邻居丰满的奶水| 免费毛片a线观看| 超薄丝袜足j好爽在线观看|