在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TSC22D1 Antibody, Biotin conjugated

  • 中文名稱:
    TSC22D1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA623011LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TSC22D1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TSC22D1
  • 別名:
    Cerebral protein 2 antibody; DKFZp686O19206 antibody; Hucep 2 antibody; Hucep2 antibody; KIAA1994 antibody; MGC17597 antibody; OTTHUMP00000040978 antibody; Ptg 2 antibody; Regulatory protein TSC 22 antibody; Regulatory protein TSC-22 antibody; Regulatory protein TSC22 antibody; RP11 269C23.2 antibody; T22D1_HUMAN antibody; TGFB stimulated clone 22 homolog antibody; TGFB-stimulated clone 22 homolog antibody; TGFB1I4 antibody; TGFbeta stimulated clone 22 antibody; Transcriptional regulator TSC 22 antibody; Transforming growth factor beta 1 induced transcript 4 antibody; Transforming growth factor beta 1 induced transcript 4 protein antibody; Transforming growth factor beta stimulated protein TSC 22 antibody; Transforming growth factor beta-1-induced transcript 4 protein antibody; TSC 22 antibody; TSC22 antibody; TSC22 domain family 1 isoform 2 antibody; TSC22 domain family member 1 antibody; TSC22 domain family protein 1 antibody; TSC22D1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TSC22 domain family protein 1 protein (1-144AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
  • 基因功能參考文獻:
    1. TSC22 could suppress tumor by inhibiting cell proliferation in colorectal cancer cell lines. Multivariate Cox regression analysis confirmed TSC22 expression as independent predictors of the OS in CRC patients PMID: 29481799
    2. TSC-22 acts as a tumor suppressor by safeguarding p53 from poly-ubiquitination mediated-degradation. PMID: 22870275
    3. we report that induced Tsc-22 leads to enhancement of TGF-beta-dependent signaling and enhancement is blocked by expression of a dominant-negative Tsc-22 mutant PMID: 21881999
    4. Differential regulation of antagonistic TSC22D1 variants is required for the establishment of oncogene-induced cellular senescence. PMID: 21448135
    5. Results support role of TSC22D1 as an enhancer of CNP transcription and suggest that TGF-beta-induced upregulation of CNP expression in smooth muscle may be mediated in part by increased transcription of TSC22D1. PMID: 20802130
    6. Long form of TSC22DF is evolutionarily conserved and has growth-regulating potential. PMID: 20149264
    7. Leucine Zipper structure of TSC22 markedly inhibits the anchorage independent growth of salivary gland cancer cells PMID: 11836610
    8. TSC-22 is an important downstream component of PPARgamma and TGF-beta signaling during intestinal epithelial cell differentiation PMID: 12468551
    9. findings suggest that the TSC-22 gene (-396) A allele is associated with an increasing risk of diabetic nephropathy PMID: 12757981
    10. Upregulation of TSC-22 mRNA by TGF-beta 1 is achieved by mRNA stabilization. PMID: 12767908
    11. Tsc-22 modulates the TGF-beta-dependant signaling pathway and binds to and modulate the transcriptional activity of Smad3 and Smad4. It has effect on cellular differentiation PMID: 15881652
    12. expression of TSC-22 in prostate is restricted to basal layer; maybe useful marker for differentation between normal and malignant acinar epithelium of prostate PMID: 16106424
    13. TSC-22 is a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD PMID: 17690703
    14. Expression of TSC-22 was frequently observed in the tumor cells with differentiated-phenotypes, although rarely in the cells with growing potentials. PMID: 18288391
    15. interaction between fortilin and TSC-22 prevents apoptosis via the destabilization of TSC-22 in ovarian carcinoma cells PMID: 18325344

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    TSC-22/Dip/Bun family
  • 組織特異性:
    Widely expressed in fetal and adult tissues.
  • 數據庫鏈接:

    HGNC: 16826

    OMIM: 607715

    KEGG: hsa:8848

    STRING: 9606.ENSP00000397435

    UniGene: Hs.436383



主站蜘蛛池模板: 亚洲中文字幕在线精品2021| 国产精品高潮呻吟av久久4虎| 337p人体 欧洲人体 亚洲| 欧美国产日韩亚洲中文| 欧美xxxx做受欧美88| 精品人妻av一区二区三区| 无码国产精品一区二区免费vr| 国产免费又色又爽又黄软件| 国产乱人伦偷精品视频下| 男人女人做爽爽18禁网站| 成年美女黄网站色大片免费看| 久久无码国产专区精品| 免费的av网站在线观看国产精品| 伊人久久精品无码麻豆一区| 亚洲综合色成在线播放| 狠狠色丁香婷婷久久综合| 久久青青草原精品国产app| 性暴力欧美猛交在线播放| 亚洲欧美乱日韩乱国产| 无码av天天av天天爽| 亚洲孰妇无码av在线播放| 国产啪精品视频网站免费尤物| 国产人与zoxxxx另类| 少妇被粗大的猛进69视频| 欧美亚洲国产手机在线有码| av无码久久久久不卡网站蜜桃| 少妇久久久久久被弄到高潮| 欧美xxxx做受欧美1314| 久9视频这里只有精品试看| 国产农村妇女毛片精品久久| 狠狠色丁香久久婷婷综合图片| 久久大蕉香蕉免费| 国产无套露脸在线观看| 熟妇女人妻丰满少妇中文字幕| 亚洲女教师丝祙在线播放| 久久99日韩国产精品久久99| 小罗莉极品一线天在线| 成人精品视频一区二区三区| 337p日本大胆欧久久| 国产精品视频二区不卡| 日本护士╳╳╳hd少妇|