在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM39 Antibody

TRIM39 Antibody

  • 中文名稱：
    TRIM39兔多克隆抗體
  • 貨號：
    CSB-PA881029LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, NIH/3T3 whole cell lysate, Mouse skeletal muscle tissue
      All lanes: TRIM39 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 60, 57 kDa
      Observed band size: 45, 50 kDa
    • IHC image of CSB-PA881029LA01HU diluted at 1:600 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescent analysis of Hela cells using CSB-PA881029LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TRIM39 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM39
  • 別名：
    HGNC:10065 antibody; MGC32984 antibody; RING finger protein 23 antibody; RNF23 antibody; Testis abundant finger protein antibody; Testis-abundant finger protein antibody; TFP antibody; TFP RING FINGER PROTEIN 23 antibody; TRI39_HUMAN antibody; Trim39 antibody; TRIM39B antibody; Tripartite motif containing 39 antibody; Tripartite motif-containing protein 39 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase TRIM39 protein (310-416AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TRIM39 Antibody (CSB-PA881029LA01HU)，的標記方式是Non-conjugated。對于TRIM39 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA881029LB01HU TRIM39 Antibody, HRP conjugated ELISA
    FITC CSB-PA881029LC01HU TRIM39 Antibody, FITC conjugated
    Biotin CSB-PA881029LD01HU TRIM39 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
    IF 1:50-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation.; Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation. Negatively regulates the canonical NF-kappa-B signaling pathway via stabilization of CACTIN in an ubiquitination-independent manner.
  • 基因功能參考文獻：
    1. TRIM39 negatively regulates the NFkappaB signaling pathway possibly via stabilization of cactin. PMID: 26363554
    2. TRIM39R, but not TRIM39B, regulates type I interferon response PMID: 23707810
    3. TRIM39 has a role in regulating cell cycle progression and the balance between cytostasis and apoptosis after DNA damage via stabilizing p21 PMID: 23213251
    4. analysis of ubiquitylation of p53 by the APC/C inhibitor Trim39 PMID: 23213260
    5. these findings suggest that RNF39 and TRIM39 are involved in the etiology of Behcet's disease. PMID: 20875797
    6. Data suggest that TRIM39 can promote apoptosis signalling through stabilization of MOAP-1. PMID: 19100260

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cytoplasm, cytosol. Mitochondrion. Nucleus.; [Isoform 2]: Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • 數據庫鏈接：

    HGNC: 10065

    OMIM: 605700

    KEGG: hsa:56658

    STRING: 9606.ENSP00000365844

    UniGene: Hs.413493



主站蜘蛛池模板： 九九热线有精品视频| 丰满人妻被中出中文字幕| 精品夜夜澡人妻无码av| 欧美性猛交xxx嘿人猛交| 国语自产偷拍精品视频蜜芽| 国产精品久久久久久2021| 国偷自产av一区二区三区| 天天看片视频免费观看| 国产在线观看高清视频黄网| 国产一区二区三区无码免费| 又大又长粗又爽又黄少妇视频| 99er国产这里只有精品视频免费| 亚洲熟妇av一区二区三区浪潮| 精品国产一区二区三区免费| 色婷婷av久久久久久久| 大桥未久亚洲一区二区| 久久只有这里有精品4| 亚洲精品无码久久| 中文字幕人成乱码熟女app| 国产成人毛片在线视频软件| 日本一本一区二区免费播放| 第九色区av天堂| 精品久久久久久无码专区| 100禁毛片免费40分钟视频| 国产乱码二卡3卡四卡| 亚洲男人av香蕉爽爽爽爽| 日韩国产高清一区二区| 18禁精品久久久国产精品久久久| 国产天堂亚洲国产碰碰| 国产精品成人免费一区久久羞羞| 国产亚洲欧洲日韩在线...| 国产精品aⅴ在线观看| 一本一本久久a久久精品综合麻豆| 国产亚洲精品美女久久久久| 国产精品人妻久久毛片| 国语少妇高潮对白在线| 秋霞特色aa大片| 欧美日韩国产一区二区三区不卡 | 国产精品毛片大码女人| 男人扒开添女人下部免费视频| 国产在线观看免费视频软件|