在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM39 Antibody, FITC conjugated

TRIM39 Antibody, FITC conjugated

  • 中文名稱：
    TRIM39兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA881029LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIM39 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM39
  • 別名：
    HGNC:10065 antibody; MGC32984 antibody; RING finger protein 23 antibody; RNF23 antibody; Testis abundant finger protein antibody; Testis-abundant finger protein antibody; TFP antibody; TFP RING FINGER PROTEIN 23 antibody; TRI39_HUMAN antibody; Trim39 antibody; TRIM39B antibody; Tripartite motif containing 39 antibody; Tripartite motif-containing protein 39 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase TRIM39 protein (310-416AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation.; Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation. Negatively regulates the canonical NF-kappa-B signaling pathway via stabilization of CACTIN in an ubiquitination-independent manner.
  • 基因功能參考文獻：
    1. TRIM39 negatively regulates the NFkappaB signaling pathway possibly via stabilization of cactin. PMID: 26363554
    2. TRIM39R, but not TRIM39B, regulates type I interferon response PMID: 23707810
    3. TRIM39 has a role in regulating cell cycle progression and the balance between cytostasis and apoptosis after DNA damage via stabilizing p21 PMID: 23213251
    4. analysis of ubiquitylation of p53 by the APC/C inhibitor Trim39 PMID: 23213260
    5. these findings suggest that RNF39 and TRIM39 are involved in the etiology of Behcet's disease. PMID: 20875797
    6. Data suggest that TRIM39 can promote apoptosis signalling through stabilization of MOAP-1. PMID: 19100260

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cytoplasm, cytosol. Mitochondrion. Nucleus.; [Isoform 2]: Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10065

    OMIM: 605700

    KEGG: hsa:56658

    STRING: 9606.ENSP00000365844

    UniGene: Hs.413493



主站蜘蛛池模板： 亚洲精品国产精品乱码视色| 中国少妇内射xxxhd免费| 一边捏奶一边高潮视频| 一本无码久本草在线中文字幕dvd| 爽爽精品dvd蜜桃成熟时电影院| 国产成人免费97在线观看| av色国产色拍| 少妇久久久久久人妻无码| 综合亚洲桃色第一影院| 国产又粗又猛又大爽又黄| 精品无码久久久久久久久| 久久精品国产男包| 中文字幕制服丝袜人妻动态图| 久久伊人蜜桃av一区二区| 久久无码av三级| 日本妇人成熟免费视频| 精品性影院一区二区三区内射| 欧美亚洲精品一区二区| 成品人视频ww入口| 国产亚洲产品影视在线产品| 无码熟妇人妻av在线网站| 丝袜 亚洲 另类 欧美 变态| 中文在线а√天堂| 国产jjzzjjzz视频全部免费| 丝袜老师高潮呻吟高潮| 真人床震高潮全部视频免费| 国产无套中出学生姝| 海角社区在线视频播放观看| 国产av老师丝袜美腿丝袜| 精品一区国产vr| 97精品国产手机| 无码av天天av天天爽| 99久视频只有精品2019| 欧美一区二区三区红桃小说| 日日狠狠久久8888偷偷色| 久久久橹橹橹久久久久高清| 成人影院永久免费观看网址| 欧美精品一区二区黄a片| 精品人妻一区二区三区四区| 国产欧美另类精品久久久| 一个人看的免费高清www视频|