在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM39 Antibody, FITC conjugated

TRIM39 Antibody, FITC conjugated

  • 中文名稱：
    TRIM39兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA881029LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIM39 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM39
  • 別名：
    HGNC:10065 antibody; MGC32984 antibody; RING finger protein 23 antibody; RNF23 antibody; Testis abundant finger protein antibody; Testis-abundant finger protein antibody; TFP antibody; TFP RING FINGER PROTEIN 23 antibody; TRI39_HUMAN antibody; Trim39 antibody; TRIM39B antibody; Tripartite motif containing 39 antibody; Tripartite motif-containing protein 39 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase TRIM39 protein (310-416AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation.; Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation. Negatively regulates the canonical NF-kappa-B signaling pathway via stabilization of CACTIN in an ubiquitination-independent manner.
  • 基因功能參考文獻：
    1. TRIM39 negatively regulates the NFkappaB signaling pathway possibly via stabilization of cactin. PMID: 26363554
    2. TRIM39R, but not TRIM39B, regulates type I interferon response PMID: 23707810
    3. TRIM39 has a role in regulating cell cycle progression and the balance between cytostasis and apoptosis after DNA damage via stabilizing p21 PMID: 23213251
    4. analysis of ubiquitylation of p53 by the APC/C inhibitor Trim39 PMID: 23213260
    5. these findings suggest that RNF39 and TRIM39 are involved in the etiology of Behcet's disease. PMID: 20875797
    6. Data suggest that TRIM39 can promote apoptosis signalling through stabilization of MOAP-1. PMID: 19100260

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cytoplasm, cytosol. Mitochondrion. Nucleus.; [Isoform 2]: Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10065

    OMIM: 605700

    KEGG: hsa:56658

    STRING: 9606.ENSP00000365844

    UniGene: Hs.413493



主站蜘蛛池模板： 东北老女人高潮大喊舒服死了| 精品无码av无码专区| 久久综合五月丁香久久激情| 国产公开久久人人97超碰 | 人妻在卧室被老板疯狂进入| 欧美人与动牲交a欧美精品| 久久婷婷色香五月综合缴缴情| 另类亚洲小说图片综合区| 亚洲成a人片在线观看你懂的| 鲁丝一区二区三区免费| 国产欧美va欧美va香蕉在线观看| 狠狠色丁香五月综合缴情婷婷五月| 最新精品国偷自产在线美女足| 人妻丰满熟妇aⅴ无码| 国产午夜精品久久精品电影 | 高清破外女出血av毛片| 国产成+人+综合+亚洲欧美 | 污污污污污污www网站免费| 久久www成人_看片免费不卡| 午夜性色吃奶添下面69影院| 国产无遮挡a片无码免费软件| 国产精品白丝喷水在线观看| 日产无码中文字幕av| 九九久久精品国产免费看小说| 久久久久久久性潮| 尤物视频在线观看| 一区二区视频传媒有限公司| 久久天天躁狠狠躁夜夜爽| 日本熟妇浓毛| 18禁黄无遮挡网站免费| 精品无码一区在线观看| 成视频年人黄网站免费视频| 欧美老妇与zozozo交| 国产成人精品一区二区视频| 涩欲国产一区二区三区四区| 少妇熟女高潮流白浆| 欧美色欧美亚洲高清在线观看| 亚洲色无码专区在线观看| 一本一道久久综合狠狠老| 在线 无码 中文字幕 强 乱| 亚洲r成人av久久人人爽|