在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM39 Antibody

TRIM39 Antibody

  • 中文名稱：
    TRIM39兔多克隆抗體
  • 貨號：
    CSB-PA024476GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM39
  • 別名：
    HGNC:10065 antibody; MGC32984 antibody; RING finger protein 23 antibody; RNF23 antibody; Testis abundant finger protein antibody; Testis-abundant finger protein antibody; TFP antibody; TFP RING FINGER PROTEIN 23 antibody; TRI39_HUMAN antibody; Trim39 antibody; TRIM39B antibody; Tripartite motif containing 39 antibody; Tripartite motif-containing protein 39 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TRIM39
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation.; Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation. Negatively regulates the canonical NF-kappa-B signaling pathway via stabilization of CACTIN in an ubiquitination-independent manner.
  • 基因功能參考文獻：
    1. TRIM39 negatively regulates the NFkappaB signaling pathway possibly via stabilization of cactin. PMID: 26363554
    2. TRIM39R, but not TRIM39B, regulates type I interferon response PMID: 23707810
    3. TRIM39 has a role in regulating cell cycle progression and the balance between cytostasis and apoptosis after DNA damage via stabilizing p21 PMID: 23213251
    4. analysis of ubiquitylation of p53 by the APC/C inhibitor Trim39 PMID: 23213260
    5. these findings suggest that RNF39 and TRIM39 are involved in the etiology of Behcet's disease. PMID: 20875797
    6. Data suggest that TRIM39 can promote apoptosis signalling through stabilization of MOAP-1. PMID: 19100260

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cytoplasm, cytosol. Mitochondrion. Nucleus.; [Isoform 2]: Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • 數據庫鏈接：

    HGNC: 10065

    OMIM: 605700

    KEGG: hsa:56658

    STRING: 9606.ENSP00000365844

    UniGene: Hs.413493



主站蜘蛛池模板： 久久综合给合久久狠狠狠97色| 最新777第四色米奇影视| 人妻少妇久久中文字幕| 巨爆乳中文字幕爆乳区| 一本一道av无码中文字幕| 女人高潮抽搐潮喷小视频| 国产免费高清69式视频在线观看| 国产伦孑沙发午休精品| 亚洲欧美一区二区三区在线| 三级成年网站在线观看级爱网| 欧美老妇乱辈通奷| 人人人妻人人澡人人爽欧美一区| 国产午夜福利片| 日本妇人成熟免费中文字幕| 国产成人三级在线视频网站观看 | 欧美日韩亚洲国内综合网| 久久久国产精品消防器材| 欧美不卡无线在线一二三区观| 麻豆视传媒官网免费观看| 欧美日韩中文国产一区发布| 免费无码又爽又刺激高潮视频| 色多多成视频人在线观看| 成人乱码一区二区三区av66| 吸咬奶头狂揉60分钟视频| 熟妇人妻无码xxx视频| 男人的天堂免费一区二区视频| 男女啪啪永久免费网站| 国自产拍偷拍精品啪啪一区二区 | 精品国产国语对白久久免费| 久久97久久97精品免视看| 国产乱人伦精品一区二区| 亚洲综合精品伊人久久| 国产高清露脸孕妇系列| 青青草原综合久久大伊人精品| 色老久久精品偷偷鲁| 亚洲精品suv精品一区二区| 亚洲国产美女精品久久久久| 暖暖视频日本在线观看| 欧洲熟妇色xxxxx视频| 偷柏自拍亚洲综合在线| 疯狂做受xxxx高潮视频免费|