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  4. TPSB2 Antibody, Biotin conjugated

TPSB2 Antibody, Biotin conjugated

  • 中文名稱：
    TPSB2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA024128LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TPSB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TPSB2
  • 別名：
    Mast cell tryptase beta II antibody; Mast cell tryptase beta III antibody; TPS2 antibody; TPSB2 antibody; TRYB2_HUMAN antibody; Tryptase beta 2 (gene/pseudogene) antibody; Tryptase beta-2 antibody; Tryptase II antibody; Tryptase-2 antibody; TryptaseB antibody; TryptaseC antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tryptase beta-2 protein (31-275AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
  • 基因功能參考文獻：
    1. These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. PMID: 24142694
    2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. PMID: 15567416
    3. The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. PMID: 17449330
    4. Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. PMID: 19748655
  • 亞細胞定位：
    Secreted. Note=Released from the secretory granules upon mast cell activation.
  • 蛋白家族：
    Peptidase S1 family, Tryptase subfamily
  • 數據庫鏈接：

    HGNC: 14120

    OMIM: 191081

    KEGG: hsa:64499

    UniGene: Hs.405479



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