在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TPP2 Antibody

  • 中文名稱:
    TPP2兔多克隆抗體
  • 貨號:
    CSB-PA024114GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TPP2
  • 別名:
    TPP2 antibody; Tripeptidyl-peptidase 2 antibody; TPP-2 antibody; EC 3.4.14.10 antibody; Tripeptidyl aminopeptidase antibody; Tripeptidyl-peptidase II antibody; TPP-II antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TPP2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis.
  • 基因功能參考文獻:
    1. TPP2 mediates many important cellular functions by controlling ERK1 and ERK2 phosphorylation. PMID: 26041847
    2. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings. PMID: 25414442
    3. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans. PMID: 25525876
    4. TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. PMID: 25303791
    5. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases. PMID: 22266401
    6. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC) activation. PMID: 22986808
    7. obtained a 3D structure of the human TPPII PMID: 22483107
    8. Current knowledge about TPPII with a focus on structural aspects. PMID: 21771670
    9. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy. PMID: 21134372
    10. the promoter could be localized to a 215 bp fragment upstream of the initiation codon. PMID: 15716107
    11. TPPII appears to promote malignant cell growth by allowing exit from mitosis and the survival of cells with severe mitotic spindle damage. PMID: 16762321
    12. TPP2 plays a specialized role in antigen processing and one that is not essential for the generation of most presented peptides. PMID: 16849449
    13. This investigation reveals that TPP II expression could be regulated through both positive and negative regulatory elements. PMID: 17343995
    14. Expression of mRNA for MuRF-1 increased approximately 3-fold at 10 days without changes in MAFbx or tripeptidyl peptidase II mRNA, but all decreased between 10 and 21 days of muscle disuse. PMID: 17901116
    15. Results indicate that TPPII is dispensable for the generation of proteasome-dependent HLA class I ligands and, the enzyme is not involved significantly in generating the proteasome-independent HLA-B27-bound peptide repertoire. PMID: 18286573
    16. Cross-presentation of NY-ESO-1/ISCOMATRIX cancer vaccine was proteasome independent and requires the cytosolic protease tripeptidyl peptidase II. PMID: 19155470
    17. MHC class I-restricted LMP1 epitopes studied in this work are two of very few epitopes known to date to be processed proteasome independently by tripeptidyl peptidase II. PMID: 19587004

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Note=Translocates to the nucleus in responce to gamma-irradiation.
  • 蛋白家族:
    Peptidase S8 family
  • 數據庫鏈接:

    HGNC: 12016

    OMIM: 190470

    KEGG: hsa:7174

    STRING: 9606.ENSP00000365233

    UniGene: Hs.432424



主站蜘蛛池模板: 在线不卡日本v二区到六区| 窝窝午夜色视频国产精品破 | 国产成人精品久久| 国产激情视频一区二区三区| 日日做夜狠狠爱欧美黑人| 黑人与人妻无码中字视频| 无码超乳爆乳中文字幕| 国产麻豆精品一区二区三区v视界| 成人亚洲欧美一区二区三区| 欧美性猛交xxxx三人| 综合五月激情二区视频| 日韩综合夜夜香内射| 精品久久久久久久久午夜福利| 欧美成人性做爰77777| 亚洲色丰满少妇高潮18p| 国产人妻人伦精品1国产| 扒开双腿猛进入喷水高潮叫声| 久久国产高潮流白浆免费观看| 亚洲a∨无码无在线观看| 亚洲国产精彩中文乱码av| 无码无套少妇18p在线直播| 手机看片久久国产免费| 人妻大战黑人白浆狂泄| 精品一区二区三人妻视频 | 久久老子午夜精品无码怎么打| 国产在线乱子伦一区二区| 国产亚洲精品久久久久蜜臀| 蜜臀亚洲精品国产aⅴ综合第一| 97久久超碰精品视觉盛宴| 色老头在线一区二区三区| 国精产品999国精产| 99久久免费国产精品| 日本乱码伦午夜福利在线| 国产精品天干天干有线观看| 免费国产h视频在线观看| 日韩精品电影综合区亚洲| 久久综合久久久久88| 一本一道vs无码中文字幕| 国产美女精品中文网蜜芽宝贝| 日本饥渴人妻欲求不满| 国产精品亚洲片在线观看不卡|