在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TPP2 Antibody, Biotin conjugated

  • 中文名稱:
    TPP2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA024114LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TPP2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TPP2
  • 別名:
    Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II), TPP2
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tripeptidyl-peptidase 2 protein (1-300aa)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis.
  • 基因功能參考文獻:
    1. TPP2 mediates many important cellular functions by controlling ERK1 and ERK2 phosphorylation. PMID: 26041847
    2. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings. PMID: 25414442
    3. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans. PMID: 25525876
    4. TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. PMID: 25303791
    5. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases. PMID: 22266401
    6. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC) activation. PMID: 22986808
    7. obtained a 3D structure of the human TPPII PMID: 22483107
    8. Current knowledge about TPPII with a focus on structural aspects. PMID: 21771670
    9. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy. PMID: 21134372
    10. the promoter could be localized to a 215 bp fragment upstream of the initiation codon. PMID: 15716107
    11. TPPII appears to promote malignant cell growth by allowing exit from mitosis and the survival of cells with severe mitotic spindle damage. PMID: 16762321
    12. TPP2 plays a specialized role in antigen processing and one that is not essential for the generation of most presented peptides. PMID: 16849449
    13. This investigation reveals that TPP II expression could be regulated through both positive and negative regulatory elements. PMID: 17343995
    14. Expression of mRNA for MuRF-1 increased approximately 3-fold at 10 days without changes in MAFbx or tripeptidyl peptidase II mRNA, but all decreased between 10 and 21 days of muscle disuse. PMID: 17901116
    15. Results indicate that TPPII is dispensable for the generation of proteasome-dependent HLA class I ligands and, the enzyme is not involved significantly in generating the proteasome-independent HLA-B27-bound peptide repertoire. PMID: 18286573
    16. Cross-presentation of NY-ESO-1/ISCOMATRIX cancer vaccine was proteasome independent and requires the cytosolic protease tripeptidyl peptidase II. PMID: 19155470
    17. MHC class I-restricted LMP1 epitopes studied in this work are two of very few epitopes known to date to be processed proteasome independently by tripeptidyl peptidase II. PMID: 19587004

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Note=Translocates to the nucleus in responce to gamma-irradiation.
  • 蛋白家族:
    Peptidase S8 family
  • 數據庫鏈接:

    HGNC: 12016

    OMIM: 190470

    KEGG: hsa:7174

    STRING: 9606.ENSP00000365233

    UniGene: Hs.432424



主站蜘蛛池模板: 亚洲精品一区二区三区新线路| 国产精品门事件av| 国产末成年女av片一区二区| 最近免费中文字幕mv在线视频3| 男女裸交免费无遮挡全过程| 永久免费无码成人网站| 日韩av无码一区二区三区无码 | 中国熟女仑乱hd| 亚洲成a人v欧美综合天堂麻豆| 久久99精品久久久久久秒播| 风韵犹存丰满大屁股熟妇| 午夜视频在线在免费| 欧美在线观看免费专区| 亚洲午夜久久久影院伊人| 国产 在线 | 日韩| 国内精品久久久久伊人av| 久久久久国产精品人妻aⅴ毛片 | 日韩a片无码毛片免费看| 无码137片内射在线影院| 丝袜老师办公室里做好紧好爽| 学生精品国产在线视频| 顶级欧美做受xxx000| 窝窝午夜看片| 国产精品国色综合久久| 97人妻无码专区| 亚洲伊人久久精品酒店| 欧美 日韩 国产 亚洲 色| 国产美女被遭强高潮免费网站| 国产初高中生粉嫩无套第一次| 国产美女裸身网站免费观看视频| 国产精品厕所| 自拍偷在线精品自拍偷无码专区| 欧美亚洲偷图色综合| 超薄丝袜足j好爽在线观看| 伊人久久综合色| 日本肥老妇色xxxxx日本老妇| 成人午夜看黄在线尤物成人| 国产亚洲日韩欧美另类丝瓜app| 国产性色αv视频免费 | 久久久免费无码成人影片| 精品久久久久久久久久中文字幕|