在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Tripeptidyl-peptidase 2 (TPP2), partial

  • 中文名稱:
    人TPP2重組蛋白
  • 貨號:
    CSB-YP024114HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TPP2重組蛋白
  • 貨號:
    CSB-EP024114HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TPP2重組蛋白
  • 貨號:
    CSB-MP024114HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TPP2
  • Uniprot No.:
  • 別名:
    TPP2; Tripeptidyl-peptidase 2; TPP-2; EC 3.4.14.10; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase II; TPP-II
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis.
  • 基因功能參考文獻(xiàn):
    1. TPP2 mediates many important cellular functions by controlling ERK1 and ERK2 phosphorylation. PMID: 26041847
    2. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings. PMID: 25414442
    3. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans. PMID: 25525876
    4. TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. PMID: 25303791
    5. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases. PMID: 22266401
    6. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC) activation. PMID: 22986808
    7. obtained a 3D structure of the human TPPII PMID: 22483107
    8. Current knowledge about TPPII with a focus on structural aspects. PMID: 21771670
    9. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy. PMID: 21134372
    10. the promoter could be localized to a 215 bp fragment upstream of the initiation codon. PMID: 15716107
    11. TPPII appears to promote malignant cell growth by allowing exit from mitosis and the survival of cells with severe mitotic spindle damage. PMID: 16762321
    12. TPP2 plays a specialized role in antigen processing and one that is not essential for the generation of most presented peptides. PMID: 16849449
    13. This investigation reveals that TPP II expression could be regulated through both positive and negative regulatory elements. PMID: 17343995
    14. Expression of mRNA for MuRF-1 increased approximately 3-fold at 10 days without changes in MAFbx or tripeptidyl peptidase II mRNA, but all decreased between 10 and 21 days of muscle disuse. PMID: 17901116
    15. Results indicate that TPPII is dispensable for the generation of proteasome-dependent HLA class I ligands and, the enzyme is not involved significantly in generating the proteasome-independent HLA-B27-bound peptide repertoire. PMID: 18286573
    16. Cross-presentation of NY-ESO-1/ISCOMATRIX cancer vaccine was proteasome independent and requires the cytosolic protease tripeptidyl peptidase II. PMID: 19155470
    17. MHC class I-restricted LMP1 epitopes studied in this work are two of very few epitopes known to date to be processed proteasome independently by tripeptidyl peptidase II. PMID: 19587004

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Note=Translocates to the nucleus in responce to gamma-irradiation.
  • 蛋白家族:
    Peptidase S8 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12016

    OMIM: 190470

    KEGG: hsa:7174

    STRING: 9606.ENSP00000365233

    UniGene: Hs.432424



主站蜘蛛池模板: 一本色道久久综合狠狠躁| 人妻少妇偷人精品视频| 女人高潮被爽到呻吟在线观看| 偷看农村女人做爰毛片色| 成人片黄网站a毛片免费观看 | 大帝a∨无码视频在线播放| 国产乡下三级全黄三级| 国产精品国产免费无码专区不卡| 伊人色综合久久天天人守人婷| 一区二区三区毛aaaa片特级| 日日夜夜撸啊撸| 97精品一区二区视频在线观看 | 国产成人av区一区二区三| 午夜少妇性影院私人影院在线| 国产精品三级在线观看无码| 四虎影视在线影院在线观看| 亚洲色无码专区一区| 日日噜狠狠噜天天噜av| 欧洲成人一区二区三区| 欧美肥胖老太vidio在线视频| h人成在线看免费视频| 性按摩玩人妻hd中文字幕| 人妻互换 综合| 午夜性色福利在线视频福利| 在线精品无码字幕无码av| 草草影院发布页| 欧美毛多水多黑寡妇| 国产无遮挡又爽又黄的视频| 亚洲第一无码xxxxxx| 人人妻人人妻人人片av| 怀孕挺大肚子疯狂高潮av毛片 | 国产真实夫妇交换视频| 欧美人妻体内射射| 欧美大片aaaaa免费观看| 人人妻人人澡人人爽人人精品av| 国产精品亚洲五月天高清| 综合色就爱涩涩涩综合婷婷| 好吊妞视频这里有精品| 国产精品一区波多野结衣| 精品亚洲国产成人av制服| 欧美成人午夜精品久久久|