在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TNS3 Antibody

  • 中文名稱:
    TNS3兔多克隆抗體
  • 貨號:
    CSB-PA731561ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA731561ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA731561ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TNS3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TNS3
  • 別名:
    TEM 6 antibody; TEM6 antibody; TENS 1 antibody; TENS 3 antibody; TENS1 antibody; TENS3 antibody; TENS3_HUMAN antibody; Tensin-3 antibody; tensin-like SH2 domain containing 1 antibody; Tensin-like SH2 domain containing protein 1 antibody; Tensin-like SH2 domain- containing protein 1 antibody; Tensin-like SH2 domain-containing protein 1 antibody; thyroid specific PTB domain protein antibody; TNS 3 antibody; TNS3 antibody; TPP antibody; Tumor endothelial marker 6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tensin-3 protein (1-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
  • 基因功能參考文獻:
    1. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells. PMID: 28515231
    2. A phosphorylation-mediated molecular switch comprising DLC), TNS3, PTEN and PI3K controls the spatiotemporal activation of Rac1 and RhoA, thereby initiating directional cell migration induced by growth factors. PMID: 26166433
    3. The depletion of tensin-3 suppressed breast cancer cell invasiveness. PMID: 25814362
    4. The phenotypic changes observed in proband cells may arise from TNS3 haploinsufficiency, causing partial loss of full-length Tensin3 protein. Tensin3 plays a rol in cytoskeletal organisation and cell motility. PMID: 23809228
    5. These results reveal a differential methylation pattern in the TNS3 promoter occurring in human renal cell carcinoma. PMID: 23803643
    6. Tensin3 may function as a platform for the disassembly of EGF-related signaling complexes at focal adhesions. PMID: 15140944
    7. Data show that EGF downregulates tensin-3 expression, and concomitantly upregulates cten, a tensin family member that lacks the actin-binding domain. PMID: 17643115
    8. TNS3-EXOC6B and EXOC6B-TNS3 fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation. PMID: 18424204
    9. Tensin3 mRNA is expressed abundantly in all twelve functional adenomas at almost the same level as in normal thyroid tissue. PMID: 18561090
    10. Tensins may represent a novel group of metastasis suppressors in the kidney, the loss of which leads to greater tumor cell motility and consequent metastasis. PMID: 19194507

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, focal adhesion.
  • 組織特異性:
    Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial
  • 數據庫鏈接:

    HGNC: 21616

    OMIM: 606825

    KEGG: hsa:64759

    STRING: 9606.ENSP00000312143

    UniGene: Hs.520814



主站蜘蛛池模板: 18禁女裸乳扒开免费视频| 自偷自拍亚洲综合精品麻豆| 无码色av一二区在线播放| 精品久久久无码中文字幕天天| 亚洲国产一区二区三区波多野结衣| 在线看片免费人成视频久网| 国产美足白丝榨精在线观看sm| 国精品午夜福利视频| 国产农村乱辈无码| 中文字幕在线日亚洲9| 顶级欧美熟妇xx| 国产成人无码精品久久久免费| 亚洲成a人v在线蜜臀| 最新国产成人无码久久| 综合亚洲伊人午夜网| 中文字幕乱码中文乱码777| 欧美肥熟妇xxxxx| 无码中文字幕免费一区二区三区 | 亚洲精品美女久久777777| 少妇又紧又深又湿又爽视频| 图片小说视频一区二区| 色与欲影视天天看综合网| 强开小婷嫩苞又嫩又紧韩国视频| 52综合精品国产二区无码| 人妻巨大乳hd免费看| 无码中文字幕日韩专区| 国产在线精品一区二区夜色| 小鲜肉洗澡时自慰网站xnxx| 日韩av片无码一区二区不卡电影 | 无码av专区丝袜专区| 试看120分钟做受小视频| 国产成人综合久久精品推下载| 亚洲图片校园另激情类小说| av鲁丝一区鲁丝二区鲁丝三区| 国产成人av大片大片在线播放| aa区一区二区三无码精片| 色在线亚洲视频www| 久久99国产乱子伦精品免费| 欧美综合自拍亚洲综合图片区| 国产免费福利在线视频| 国产成人精品日本亚洲网站|