在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TNS3 Antibody

  • 中文名稱:
    TNS3兔多克隆抗體
  • 貨號:
    CSB-PA050061
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TNS3
  • 別名:
    TEM 6 antibody; TEM6 antibody; TENS 1 antibody; TENS 3 antibody; TENS1 antibody; TENS3 antibody; TENS3_HUMAN antibody; Tensin-3 antibody; tensin-like SH2 domain containing 1 antibody; Tensin-like SH2 domain containing protein 1 antibody; Tensin-like SH2 domain- containing protein 1 antibody; Tensin-like SH2 domain-containing protein 1 antibody; thyroid specific PTB domain protein antibody; TNS 3 antibody; TNS3 antibody; TPP antibody; Tumor endothelial marker 6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Tensin3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
  • 基因功能參考文獻:
    1. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells. PMID: 28515231
    2. A phosphorylation-mediated molecular switch comprising DLC), TNS3, PTEN and PI3K controls the spatiotemporal activation of Rac1 and RhoA, thereby initiating directional cell migration induced by growth factors. PMID: 26166433
    3. The depletion of tensin-3 suppressed breast cancer cell invasiveness. PMID: 25814362
    4. The phenotypic changes observed in proband cells may arise from TNS3 haploinsufficiency, causing partial loss of full-length Tensin3 protein. Tensin3 plays a rol in cytoskeletal organisation and cell motility. PMID: 23809228
    5. These results reveal a differential methylation pattern in the TNS3 promoter occurring in human renal cell carcinoma. PMID: 23803643
    6. Tensin3 may function as a platform for the disassembly of EGF-related signaling complexes at focal adhesions. PMID: 15140944
    7. Data show that EGF downregulates tensin-3 expression, and concomitantly upregulates cten, a tensin family member that lacks the actin-binding domain. PMID: 17643115
    8. TNS3-EXOC6B and EXOC6B-TNS3 fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation. PMID: 18424204
    9. Tensin3 mRNA is expressed abundantly in all twelve functional adenomas at almost the same level as in normal thyroid tissue. PMID: 18561090
    10. Tensins may represent a novel group of metastasis suppressors in the kidney, the loss of which leads to greater tumor cell motility and consequent metastasis. PMID: 19194507

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, focal adhesion.
  • 組織特異性:
    Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial
  • 數據庫鏈接:

    HGNC: 21616

    OMIM: 606825

    KEGG: hsa:64759

    STRING: 9606.ENSP00000312143

    UniGene: Hs.520814



主站蜘蛛池模板: 无码中文字幕av免费放| 理论片87福利理论电影| 久久久中文字幕日本无吗| 曰本一道本久久88不卡| 国产精品99久久久久久宅男小说| 亚洲成av人的天堂在线观看| 无遮挡边摸边吃奶边做视频| 日韩精品无码专区免费视频| 真实国产乱子伦在线视频| 秋霞av鲁丝片一区二区| 欧美人与动牲交a欧美精品| 韩国午夜福利片在线观看| 日韩av无码中文无码电影| 国产九九九九九九九a片| 欧美性生交大片18禁止| 无码专区—va亚洲v天堂麻豆| 免费永久在线观看黄网站| 亚洲一区二区三区尿失禁| 久久综合九色欧美综合狠狠 | 色综合网天天综合色中文| 国内精品一区二区三区不卡| 欧美日韩中文国产一区发布 | 正在播放酒店约少妇高潮| 国产乱人伦无无码视频试看| 国产精品对白交换视频| 亚洲一区波多野结衣在线| 亚洲色精品88色婷婷七月丁香| 国产成人无码a区精油按摩| 国产精品igao视频网| 天堂а√中文在线| 特级毛片a片久久久久久| 国产成人无码专区| 久久婷婷丁香七月色综合| 免费国产线观看免费观看| 欧美老熟妇videos极品另类| 97超碰精品成人国产| 两个男人吮她的花蒂和奶水视频| 亚洲欭美日韩颜射在线二| 影音先锋男人站| 亚洲精品卡一卡三卡四卡乱码| 色欲狠狠躁天天躁无码中文字幕|