在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNFRSF10C Antibody, FITC conjugated

TNFRSF10C Antibody, FITC conjugated

  • 中文名稱：
    TNFRSF10C兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA08189C0Rb
  • 規(guī)格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TNFRSF10C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    TNFRSF10C antibody; DCR1 antibody; LIT antibody; TRAILR3 antibody; TRID antibody; UNQ321/PRO366 antibody; Tumor necrosis factor receptor superfamily member 10C antibody; Antagonist decoy receptor for TRAIL/Apo-2L antibody; Decoy TRAIL receptor without death domain antibody; Decoy receptor 1 antibody; DcR1 antibody; Lymphocyte inhibitor of TRAIL antibody; TNF-related apoptosis-inducing ligand receptor 3 antibody; TRAIL receptor 3 antibody; TRAIL-R3 antibody; TRAIL receptor without an intracellular domain antibody; CD antigen CD263 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tumor necrosis factor receptor superfamily member 10C protein (26-236AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
  • 基因功能參考文獻：
    1. High levels of TRAIL-R3 and CCR-2 expression in tumor epithelial cells identified patients with early breast cancer with poor outcomes. PMID: 28420351
    2. DcR1 levels in serum sample which were significantly lower in AMD patients. PMID: 24534820
    3. DcR1 upregulation mediates temozolomide resistance. PMID: 25808868
    4. GATA4 and DcR1 promoter hypermethylation is tumor specific event in glioblastoma but they promoter methylation cannot be considered as a prognostic marker of glioblastoma survival. PMID: 23320456
    5. Primary EOC is associated to a lower TRAIL-R3 expression. PMID: 22555108
    6. Data show that about 20% of AML patients highly expressed decoy receptor TRAIL-R3, which was strongly correlated to a shortened overall survival. PMID: 21281967
    7. Decoy receptors DcR1 and DcR2 on CD8+ T cells, but not on CD4-positive T cells, are positively correlated with patients' DAS scores. PMID: 20799941
    8. Results suggest that DcR1 expression occurs in a subset of endometrial carcinomas and may contribute to resistance to TRAIL-induced apoptosis. PMID: 19936781
    9. analysis of the transcription initiation sites and promoter structure of the TRAIL-R3 gene PMID: 12417331
    10. cloned and characterized a p53 consensus element located within the first intron of the TRAIL-R3 gene PMID: 14623878
    11. Our results demonstrate that DcR1 and DcR2 genes are frequently methylated in various tumor types, and aberrant methylation was the cause for silencing of DcR1 and DcR2 expression. PMID: 14999791
    12. The DcR1 had no death domain and was anchored to the membrane via a glycophosphatidyl inositol tail. PMID: 15538968
    13. Resistance to TRAIL-induced apoptosis in acute myeloid leukemia cells is associated with expression of TRAIL-R3. PMID: 15921376
    14. tryptophol induces apoptosis through DR5 and the resistance of PBL to tryptophol-induced apoptosis might be due to competition from DcR1 PMID: 17690453
    15. p53 negatively regulates oxaliplatin-mediated TRAIL-induced apoptotic activity through DcR1 upregulation. PMID: 18345033
    16. TRAILR3 (TNF-related apoptosis inducing ligand receptor 3) levels were significantly higher in lung parenchyma in subjects with emphysema PMID: 18511705
    17. Liver metastases with low DcR1/TNFRSF10C mRNA expression were more likely to present with extrahepatic metastases PMID: 18590575
    18. inactivation of TNFRSF10C by chromosomal deletion and promoter methylation may play an important role in prostate cancer development PMID: 19035483
    19. Low DCR1 is associated with non-small cell lung cancer. PMID: 19661294

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 組織特異性：
    Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11906

    OMIM: 603613

    KEGG: hsa:8794

    STRING: 9606.ENSP00000349324

    UniGene: Hs.655801



主站蜘蛛池模板： 国产精品久久久久久2021| 国产ktv交换配乱婬视频| 精品无码乱码av| 一道本在线伊人蕉无码| 国产98色在线 | 国产| 久久精品农村毛片| 末成年毛片在线播放| 国产乱人伦真实精品视频| 无码av免费精品一区二区三区| 国产香蕉国产精品偷在线| 国产午睡沙发被弄醒完整版| 亚洲色精品三区二区一区| 全部免费毛片在线播放| 国产熟妇午夜精品aaa| 成人h无码动漫超w网站| 人妻体内射精一区二区三四| 北条麻妃一区二区三区av高清| 亚洲第一最快av网站| 又大又粗又长的高潮视频| 久久婷婷国产综合精品| 吃奶呻吟打开双腿做受在线视频| 国产精品午夜爆乳美女视频| 久久久免费无码成人影片| 国产精品露脸国语对白| 国产亚洲综合网曝门系列| h漫全彩纯肉无码网站| 蜜臀精品无码av在线播放| 日本免费人成视频播放| 2019亚洲午夜无码天堂| 夜夜躁狠狠躁日日躁视频| 美女高潮黄又色高清视频免费| 日本午夜精品一区二区三区电影| 久久一卡二卡三卡四卡| 国产精品.xx视频.xxtv| 阳茎伸入女人阳道视频| 精品精品国产理论在线观看| 天天摸天天做天天爽| 日本人妻人人人澡人人爽| 国产精品99久久免费观看| 国产精品日韩欧美一区二区三区| 一本一道色欲综合网中文字幕|